Fish Cell Line As an In Vitro Test System for Analyzing Chromosome Aberrations

2001 ◽  
Vol 67 (1) ◽  
pp. 6-11
Author(s):  
Y.-B. Oh ◽  
J.-S. Lee ◽  
E.-H. Park
Keyword(s):  
Cell Line ◽  
Chromosome Aberrations ◽  
Test System ◽  
Fish Cell Line ◽  
Fish Cell ◽  
In Vitro Test ◽  
Vitro Test

A simple cell line based in vitro test system for N-methyl-d-aspartate (NMDA) receptor ligands

2002 ◽  
Vol 113 (1) ◽  
pp. 99-110 ◽  
Author(s):  
Ralf D Steinmetz ◽  
Eugenio Fava ◽  
Pierluigi Nicotera ◽  
Dieter Steinhilber
Keyword(s):  
Nmda Receptor ◽  
Cell Line ◽  
Test System ◽  
Simple Cell ◽  
In Vitro Test ◽  
Receptor Ligands ◽  
Vitro Test ◽  
Nmda Receptor Ligands

scholarly journals In vitro cytotoxic and teratogenic potential of sediment extracts from Skadar Lake using fish cell line RTL-W1 and Danio rerio embryos

2013 ◽  
Vol 65 (4) ◽  
pp. 1539-1546 ◽  
Author(s):  
Andrej Perovic ◽  
Svetlana Perovic ◽  
Thomas-Benjamin Seiler ◽  
Henner Hollert
Keyword(s):  
Cell Line ◽  
Danio Rerio ◽  
Fish Cell Line ◽  
Fish Cell ◽  
Teratogenic Potential ◽  
Danio Rerio Embryos

An in vitro test system for compounds that modulate human inflammatory macrophage polarization

2018 ◽  
Vol 833 ◽  
pp. 328-338 ◽  
Author(s):  
Hiromi Shiratori ◽  
Carmen Feinweber ◽  
Sonja Luckhardt ◽  
Nadja Wallner ◽  
Gerd Geisslinger ◽  
...  
Keyword(s):  
Macrophage Polarization ◽  
Test System ◽  
In Vitro Test ◽  
Vitro Test ◽  
Inflammatory Macrophage

Biomimetic in vitro test system for evaluation of dental implant materials

2020 ◽  
Vol 36 (8) ◽  
pp. 1059-1070
Author(s):  
Franziska Ehlicke ◽  
Jonathan Berndt ◽  
Nina Marichikj ◽  
Doris Steinmüller-Nethl ◽  
Heike Walles ◽  
...  
Keyword(s):  
Dental Implant ◽  
Test System ◽  
In Vitro Test ◽  
Implant Materials ◽  
Vitro Test

scholarly journals Prediction of in Vivo Cytotoxicity of Chemotherapeutic Agents by Their Effect on Malignant Leukocytes in Vitro

Blood ◽  
1967 ◽  
Vol 30 (2) ◽  
pp. 176-188 ◽  
Author(s):  
MARTIN J. CLINE
Keyword(s):  
Test System ◽  
Chemotherapeutic Agents ◽  
Response To Treatment ◽  
In Vitro Test ◽  
Malignant Cells ◽  
Vitro Test ◽  
In Vitro Effects ◽  
In Vivo Cytotoxicity

Abstract In order to develop a test system for predicting the response to chemotherapeutic agents, leukocytes from patients with leukemia and leukolymphosarcoma were cultured in vitro and the effect of several drugs on the incorporation of H3-uridine into ribonucleic acid was measured. Cortisol, vincristine and cytosine arabinoside at concentrations near the therapeutic range produced inhibition of H3-uridine incorporation in sensitive leukocytes. The in vitro effects of 6-mercaptopurine and methotrexate were variable. In 39 trials on 25 patients with leukemia or lymphosarcoma, the in vitro test was used successfully to predict the response to treatment with prednisone and vincristine. It was concluded that the in vitro test system can predict the in vivo cytotoxicity of certain drugs for malignant cells, although it cannot be used to predict the likelihood of the induction of remissions with these drugs.

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