scholarly journals Reduced second phase insulin secretion in carriers of a sulphonylurea receptor gene variant associating with Type II diabetes mellitus

Diabetologia ◽  
2000 ◽  
Vol 43 (4) ◽  
pp. 515-519 ◽  
Author(s):  
L. M. ’t Hart ◽  
J. M. Dekker ◽  
T. W. van Haeften ◽  
J. B. Ruige ◽  
C. D. A. Stehouwer ◽  
...  
Diabetologia ◽  
1999 ◽  
Vol 42 (5) ◽  
pp. 617-620 ◽  
Author(s):  
L. M. ’t Hart ◽  
P. de Knijff ◽  
J. M. Dekker ◽  
R. P. Stolk ◽  
G. Nijpels ◽  
...  

Diabetes ◽  
1989 ◽  
Vol 38 (8) ◽  
pp. 975-980 ◽  
Author(s):  
S. H. Raboudi ◽  
B. D. Mitchell ◽  
M. P. Stern ◽  
C. W. Eifler ◽  
S. M. Haffner ◽  
...  

Author(s):  
Manish Kumar ◽  
Lalit Mohan ◽  
Hitesh Mishra ◽  
Akash Chandra ◽  
Harihar Dikshit

Background: This study was developed to know the students’ views regarding personal drug (P-drug) concept in rational prescription of drugs and also giving them training of creating and using personal drug concept.Methods: 40 medical students (5th semester) divided in four groups were involved voluntarily in a three phase, questionnaire based and prospective study. In first and second phase students were taught and asked to derive P-drug using different standard text books and Current Index of Medical Specialties (CIMS) by analyzing efficacy, safety, cost and convenience of drugs used for type II diabetes mellitus. Third phase was designed to know the students’ perception regarding the exercise and difficulties faced in the process of P-drug selection. It contained demographic and 12 questions with answer using Likert scale.Results: Students selected biguanide (metformin) as a P-drug in terms of efficacy, safety, cost and convenience. 95% (36 out of 40) responded in the questionnaire, out of which 92% (33 out of 36) had given answer with mean score ≥4. Overall median score was 4 and Interquartile Range was 4-5. 89% (32) strongly agreed that P-dug selection teaching helped them to understand pharmacology better. Majority (83% or 30) were in favour of introducing P-drug selection exercises in undergraduate pharmacology curriculum.Conclusions: P-drug selection exercise helped students to understand the differences among various drugs used for the treatment of type II diabetes mellitus and given them a strong foundation for developing rational use of the medicine in their future career as a doctor.


Diabetes ◽  
1989 ◽  
Vol 38 (8) ◽  
pp. 975-980 ◽  
Author(s):  
S. H. Raboudi ◽  
B. D. Mitchell ◽  
M. P. Stern ◽  
C. W. Eifler ◽  
S. M. Haffner ◽  
...  

Diabetes ◽  
1985 ◽  
Vol 34 (3) ◽  
pp. 222-234 ◽  
Author(s):  
W. T. Garvey ◽  
J. M. Olefsky ◽  
J. Griffin ◽  
R. F. Hamman ◽  
O. G. Kolterman

Diabetes ◽  
1985 ◽  
Vol 34 (3) ◽  
pp. 222-234 ◽  
Author(s):  
W. T. Garvey ◽  
J. M. Olefsky ◽  
J. Griffin ◽  
R. F. Hamman ◽  
O. G. Kolterman

2013 ◽  
Vol 9 (2) ◽  
pp. 34-37 ◽  
Author(s):  
Т. Еловикова ◽  
T. Elovikova ◽  
А. Трошунин ◽  
A. Troshunin ◽  
Е. Жукова ◽  
...  

<p>Diabetes — a group of diseases characterized by hyperglycemia resulting from violations of insulin secretion, insulin action or both. The study revealed the following symptoms of the oral cavity in patients with type II diabetes mellitus: the mucous membrane swollen, pale, dry and shiny, tongue dry, wrinkled and pink, as well as poor hygiene, high intensity decay. Use mouthwash after first use showed significant improvements in the structure of the oral fluid.</p>


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