scholarly journals An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes

Diabetologia ◽  
1999 ◽  
Vol 42 (6) ◽  
pp. 688-692 ◽  
Author(s):  
P. G. Cassell ◽  
M. Neverova ◽  
S. Janmohamed ◽  
N. Uwakwe ◽  
A. Qureshi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Uncoupling Protein ◽  
Uncoupling Protein 2 ◽  
Type Ii ◽  
Gene Variant

scholarly journals Outcome of breast cancer patients regarding obesity and complications: Analysis of risk factors

2021 ◽  
Vol 68 (1) ◽  
pp. 77-86
Author(s):  
Iuliana Pantelimon ◽  
◽  
Laurentia Nicoleta Gales ◽  
Maria Daniela Tanasescu ◽  
Irina Nita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Prognostic Factors ◽  
Disease Progression ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
The Body ◽  
Proliferation Index ◽  
Her2 Overexpression ◽  
Type Ii

Introduction. Breast cancer is the leading cause of cancer death in Romania. In the context in which the treatments available for this pathology have increased curability, the identification of negative prognostic factors involved in the evolution of this disease seems essential to improve the overall survival as well as the time to disease progression. Aim. The aim of this study is to identify the role of prognostic factors such as ki67 proliferation index, the presence of tumour estrogen receptors, HER2 overexpression, the presence of secondary determinations at diagnosis, the association of obesity and type II diabetes. Methods. 50 patients diagnosed with breast cancer treated in the Elias University Emergency Hospital Bucharest were retrospectively followed, for which the progression was documented at the time of elaboration of this study. Thus, a database was developed in which data were entered on age, body mass index, immunohistochemical characteristics of breast tumours, the presence/absence of metastases at diagnosis and the association of type II diabetes. Statistical calculations were performed to highlight a possible correlation between obesity (quantified by measuring body mass index) and tumour aggressiveness (quantified by ki67 proliferation index) as well as statistical evaluation of potential prognostic factors that would influence time, until the disease progresses. Results. Within this group, no correlation could be established between the presence of an increased body mass index and the value of the ki67 proliferation index (p = 0.38). The mean value of the body mass index for this group of unselected patients was 28.76 ± 4.81 (DS) most patients are therefore overweight or obese. The factors involved in the evolution of breast cancer that influenced the early progression of the disease were: the proliferation index ki67 (p <0.05), the presence of metastases at diagnosis (p < 0.0001) and the association of type II diabetes (p = 0.0085). The value of the body mass index did not influence the time to disease progression according to statistical calculations in this group probably due to the small number of normal weight patients included (p = 0.34).

scholarly journals Risk Factors Associated With Type-II Diabetes Mellitus in Male Adults in District Mardan

2019 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Body Mass Index ◽  
Blood Sugar ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Fasting Blood Sugar ◽  
Type Ii ◽  
Factors Associated

A study was carried out, in order to assess the risk factors associated with type-II diabetes mellitus in males (Age≥40 years) in district Mardan. Four hundred cases and controls (Each 200) were selected from 10 union councils (7 rural and 3 urban) by a systematic sampling method. In order to select cases and controls, all were interviewed for medical history, on fulfillment of which, cases and controls were separately included for study. In anthropometry, weight, and height were taken for Body Mass Index while waist and hip circumference were taken for waist-to-hip ratio. Fasting blood sugar of cases and controls was determined with the glucometer. Cases and controls were interviewed with Food frequency questionnaire and other questionnaires in order to assess the demographic and socioeconomic characters of the families. The results disclosed that most of the cases had family history of diabetes. In addition to that, cases were also found to have higher (p<0.05) average weight, height and body mass index, and fasting blood sugar level to those of controls. These results also revealed that there was a distinguished (p<0.05) association between dairy and fruit with the health status and about 1/3rd of both cases and controls had satisfactory consumption of dairy and fruit only. A significant link was found among family size, exercise, type of exercise, duration of exercise, watching television, duration of watching television and the status of disease. The study revealed that a combination of anthropometric, dietary and demographic variables were associated with type-II diabetes mellitus in male adult population of district Mardan.

Achilles tendon and plantar fascia in recently diagnosed type II diabetes: role of body mass index

2012 ◽  
Vol 31 (7) ◽  
pp. 1109-1113 ◽  
Author(s):  
Michele Abate ◽  
Cosima Schiavone ◽  
Luigi Di Carlo ◽  
Vincenzo Salini
Keyword(s):  
Body Mass Index ◽  
Achilles Tendon ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Plantar Fascia ◽  
Type Ii

scholarly journals PREVALENCE OF SILENT CARDIAC ISCHEMIA IN TYPE II DIABETES MELLITUS

2021 ◽  
Vol 54 (2) ◽  
pp. 162-166
Author(s):  
Nosheen Zia ◽  
Sabeen Aftab ◽  
Nauman Ismat Butt ◽  
Fahmina Ashfaq ◽  
Aniqa Anser ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Tertiary Care ◽  
Care Facility ◽  
Type Ii Diabetes Mellitus ◽  
Cardiac Ischemia ◽  
Type Ii ◽  
Tertiary Care Facility

Objectives: To determine the frequency of silent cardiac ischemia in type II diabetes mellitus patients presenting to tertiary care facility. Methodology: This cross-sectional study was conducted from 20th October 2017 to 20th April 2018 at Department of Medicine Jinnah Hospital Lahore. After a detailed history, measurement of height, blood pressure, weight, fasting blood sugar, body mass index of 237 patients were recorded, and electrocardiography (ECG) was done before and after exercise tolerance testing (ETT). Changes in ECG were assessed and person labeled as having silent cardiac ischemia or not depending on the outcome of the ECG. Results: Mean age was 54.9 ± 5.9 (range: 45 – 63) years. There were 144 male patients and 93 female patients The mean duration of type II diabetes mellitus in the study population was 10.0 ± 2.6 (range: 6 – 15) years. The frequency of silent cardiac ischemia was found to be 45.1%. Increasing age, prolonged duration of diabetes mellitus, history of smoking and hypertension, and increased body mass index were significantly related to silent cardiac ischemia (p-value< 0.05). Conclusion: Silent cardiac is quite prevalent in our population that demands urgent efforts to diagnose this condition earlier for better future outcomes.

scholarly journals Laparoscopic Roux-en-Y Gastric Bypass for the Treatment of Type II Diabetes Mellitus in Chinese Patients with Body Mass Index of 25–35

2011 ◽  
Vol 21 (9) ◽  
pp. 1344-1349 ◽  
Author(s):  
Chih-Kun Huang ◽  
Asim Shabbir ◽  
Chi-Hsien Lo ◽  
Chi-Ming Tai ◽  
Yaw-Sen Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Gastric Bypass ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Chinese Patients ◽  
Type Ii

116 The Obesity Paradox in Type II Diabetes Mellitus. Impact of Body Mass Index on Prognosis

Heart ◽  
2014 ◽  
Vol 100 (Suppl 3) ◽  
pp. A66.1-A66 ◽  
Author(s):  
Pierluigi Costanzo ◽  
Pierpaolo Pellicori ◽  
John Cleland ◽  
Andrew Clark ◽  
David Hepburn ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Obesity Paradox ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii
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