scholarly journals Contrasting renal functional reserve in very long-term Type I diabetic patients with and without nephropathy

Diabetologia ◽  
2000 ◽  
Vol 43 (2) ◽  
pp. 227-230 ◽  
Author(s):  
H. Sackmann ◽  
T. Tran-Van ◽  
I. Tack ◽  
H. Hanaire-Broutin ◽  
J.-P. Tauber ◽  
...  
2012 ◽  
Vol 38 (1) ◽  
pp. 174-179 ◽  
Author(s):  
Jonas Vejvad Nørskov Laursen ◽  
Stine Skovbo Hoffmann ◽  
Anders Green ◽  
Mads Nybo ◽  
Anne Katrin Sjølie ◽  
...  

1987 ◽  
Author(s):  
N Montani ◽  
S B Solerte ◽  
G Gamba ◽  
M Fioravanti ◽  
E Ferrari

It is known that the increase of glomerular filtration rate (GFR) represents an early sign of diabetic nephropathy. The changes of endothelial functions observed in diabetes might play a role in this respect. As F VIII vWF and fibronectin are synthetized by endothelial cells, we evaluated these components in 33 diabetic patients with short-term Type I (insulin dependent) diabetes mellitus, without retinopathy and macro-vascular complications. 15 pts. (mean age 29 ± 7 yrs; mean diabetes duration 2.9 ± 0.9 yrs) presented high GFR (154 ± 19 ml/min per 1.73 m2 ; albuminuria 7.2 ± 3.2 μg/min) and 18 pts. (mean age 30 ± 6 yrs; mean diabetes duration 3.0 ± 1 yrs) normal GFR (105 ± 11 ml/min per 1.73 m2 ; albuminuria 5 ± 2.8 μg/min).The following results were obtained:In conclusion the significant increase of FVIIIR:Ag and fibronectin levels in short-time type I diabetic patients with high GFR suggests an early endothelial cell function damage also related to the Door metabolic control.


2020 ◽  
Vol Volume 13 ◽  
pp. 2989-2995
Author(s):  
Santosh Nagaraju ◽  
Richard S Mangus ◽  
Tyra A Salisbury ◽  
Weston J Bush ◽  
Jason P Davis ◽  
...  

2007 ◽  
Vol 22 (11) ◽  
pp. 1903-1909 ◽  
Author(s):  
Ann Raes ◽  
Raymond Donckerwolcke ◽  
Margarita Craen ◽  
Maraina Che Hussein ◽  
Johan Vande Walle

1991 ◽  
Vol 8 (S2) ◽  
pp. S43-S47 ◽  
Author(s):  
I. I. Dedov ◽  
N. A. Mukhin ◽  
M. V. Shestakova ◽  
M. A. Paltzev ◽  
V. A. Warshawskyi ◽  
...  

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