Postoperative Schmerztherapie (Postoperative pain therapy)

1997 ◽  
Vol 46 (1) ◽  
pp. 65-77 ◽  
Author(s):  
J. Jage ◽  
H. Harje
Keyword(s):  
Postoperative Pain ◽  
Pain Therapy ◽  
Postoperative Schmerztherapie ◽  
Postoperative Pain Therapy

Metamizole for postoperative pain therapy in 1177 children

2015 ◽  
Vol 32 (12) ◽  
pp. 839-843 ◽  
Author(s):  
Melanie Fieler ◽  
Christoph Eich ◽  
Karin Becke ◽  
Gregor Badelt ◽  
Klaus Leimkühler ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Pain Therapy ◽  
Postoperative Pain Therapy

Postoperative Pain Therapy by Epidural Morphine

1982 ◽  
pp. 109-113
Author(s):  
M. Zenz ◽  
S. Piepenbrock ◽  
G. Otten ◽  
M. Hüsch
Keyword(s):  
Postoperative Pain ◽  
Epidural Morphine ◽  
Pain Therapy ◽  
Postoperative Pain Therapy

Patient-controlled Analgesia with Target-controlled Infusion of Hydromorphone in Postoperative Pain Therapy

2016 ◽  
Vol 124 (1) ◽  
pp. 56-68 ◽  
Author(s):  
Christian Jeleazcov ◽  
Harald Ihmsen ◽  
Teijo I. Saari ◽  
Doris Rohde ◽  
Jan Mell ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Pain Therapy ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Plasma Concentrations ◽  
Maximum Plasma ◽  
Patient Controlled Analgesia ◽  
Postoperative Pain Therapy ◽  
Target Controlled Infusion ◽  
Plasma Target

Abstract Background Patient-controlled analgesia (PCA) is a common method for postoperative pain therapy, but it is characterized by large variation of plasma concentrations. PCA with target-controlled infusion (TCI-PCA) may be an alternative. In a previous analysis, the authors developed a pharmacokinetic model for hydromorphone. In this secondary analysis, the authors investigated the feasibility and efficacy of TCI-PCA for postoperative pain therapy with hydromorphone. Methods Fifty adult patients undergoing cardiac surgery were enrolled in this study. Postoperatively, hydromorphone was applied intravenously during three sequential periods: (1) as TCI with plasma target concentrations of 1 to 2 ng/ml until extubation; (2) as TCI-PCA with plasma target concentrations between 0.8 and 10 ng/ml during the following 6 to 8 h; and (3) thereafter as PCA with a bolus dose of 0.2 mg until the next morning. During TCI-PCA, pain was regularly assessed using the 11-point numerical rating scale (NRS). A pharmacokinetic/pharmacodynamic model was developed using ordinal logistic regression based on measured plasma concentrations. Results Data of 43 patients aged 40 to 81 yr were analyzed. The hydromorphone dose during TCI-PCA was 0.26 mg/h (0.07 to 0.93 mg/h). The maximum plasma target concentration during TCI-PCA was 2.3 ng/ml (0.9 to 7.0 ng/ml). The NRS score under deep inspiration was less than 5 in 83% of the ratings. Nausea was present in 30%, vomiting in 9%, and respiratory insufficiency in 5% of the patients. The EC50 of hydromorphone for NRS of 4 or less was 4.1 ng/ml (0.6 to 12.8 ng/ml). Conclusion TCI-PCA with hydromorphone offered satisfactory postoperative pain therapy with moderate side effects.

scholarly journals Recent Advances in Postoperative Pain Therapy for Thoracic Surgery

2014 ◽  
Vol 4 (2) ◽  
pp. 177-187
Author(s):  
Torsten Loop ◽  
Stephen Harris ◽  
Alexander Grimm
Keyword(s):  
Postoperative Pain ◽  
Thoracic Surgery ◽  
Pain Therapy ◽  
Postoperative Pain Therapy ◽  
Recent Advances

scholarly journals Organisation and methods in postoperative pain therapy

Anaesthesia ◽  
1998 ◽  
Vol 53 (S2) ◽  
pp. 47-49 ◽  
Author(s):  
T. Hartmann ◽  
C. G. Krenn ◽  
C. Preis ◽  
M. Felfernig
Keyword(s):  
Postoperative Pain ◽  
Pain Therapy ◽  
Postoperative Pain Therapy
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