Eicosanoid release in the endotoxin-primed isolated perfused rat lung and its pharmacological modification

1999 ◽  
Vol 48 (12) ◽  
pp. 632-636 ◽  
Author(s):  
R. Amann ◽  
R. Schuligoi ◽  
B. A. Peskar
Keyword(s):  
Rat Lung ◽  
Eicosanoid Release ◽  
Pharmacological Modification

scholarly journals Cyclic-AMP mediated drugs: differential or global reduction of eicosanoid synthesis in the isolated rat lung?

1992 ◽  
Vol 1 (4) ◽  
pp. 255-261
Author(s):  
Mark J. Post ◽  
Jan Dirk te Biesebeek ◽  
Johan Wemer ◽  
Hans H. van Rooij ◽  
Freek J. Zijlstra ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Rat Lung ◽  
Eicosanoid Synthesis ◽  
Eicosanoid Release ◽  
Isolated Lungs ◽  
A Site ◽  
Isolated Rat Lung ◽  
Global Reduction

In this study the question was addressed whether cAMP mediated drugs induce a differential reduction of branches of the arachidonic acid metabolism rather than a global reduction of eicosanoid synthesis. The isolated lungs of actively sensitized rats were employed to study prostaglandin and leukotriene release in the presence and absence of the cAMP mediated drugs theophylline, milrinone, sulmazole, isobutyl-methylxanthine and salbutamol. The release of eicosanoids as measured by RIA was predominantly basal and continuous, with a mild antigen induced stimulation only for TXB2and the leukotrienes. All drugs reduced eicosanoid release globally. It is concluded that cAMP mediated drugs interfere with arachidonic acid metabolism at a site proximal to the branching into lipoxygenase and cyclo-oxygenase pathways.

Replication of Internal Biological Surfaces

1972 ◽  
Vol 30 ◽  
pp. 308-309
Author(s):  
J. A. Nowell ◽  
J. Pangborn ◽  
W. S. Tyler
Keyword(s):  
Da Vinci ◽  
Leonardo Da Vinci ◽  
Rat Lung ◽  
Tubular Structures ◽  
Cerebral Ventricles ◽  
Internal Surfaces ◽  
Biological Surfaces ◽  
Dog Kidney ◽  
Lung And Kidney ◽  
Scanning Electron

Leonardo da Vinci in the 16th century, used injection replica techniques to study internal surfaces of the cerebral ventricles. Developments in replicating media have made it possible for modern morphologists to examine injection replicas of lung and kidney with the scanning electron microscope (SEM). Deeply concave surfaces and interrelationships to tubular structures are difficult to examine with the SEM. Injection replicas convert concavities to convexities and tubes to rods, overcoming these difficulties.Batson's plastic was injected into the renal artery of a horse kidney. Latex was injected into the pulmonary artery and cementex in the trachea of a cat. Following polymerization the tissues were removed by digestion in concentrated HCl. Slices of dog kidney were aldehyde fixed by immersion. Rat lung was aldehyde fixed by perfusion via the trachea at 30 cm H2O. Pieces of tissue 10 x 10 x 2 mm were critical point dried using CO2. Selected areas of replicas and tissues were coated with silver and gold and examined with the SEM.

Radiation pneumonitis in rat lung after treatment with rhenium-188-microspheres

2008 ◽  
Vol 180 (09) ◽  
Author(s):  
K Liepe ◽  
M Haase ◽  
D Faulhaber ◽  
G Wunderlich ◽  
M Andreeff ◽  
...  
Keyword(s):  
Radiation Pneumonitis ◽  
Rat Lung

Transdifferentiation of fibroblasts and myofibroblasts from rat lung

Pneumologie ◽  
2005 ◽  
Vol 59 (01) ◽  
Author(s):  
T Zimmer ◽  
KP Knoch ◽  
R Koslowski
Keyword(s):  
Rat Lung

Detection and characterization of a heat and acid stable progesterone binding protein in the rat lung

1984 ◽  
Vol 104 (4_Supplb) ◽  
pp. S91-S92
Author(s):  
G. DAXENBICHLER ◽  
E. H. MOSER
Keyword(s):  
Binding Protein ◽  
Rat Lung ◽  
Acid Stable

Maturation of fetal rat lung in diabetic pregnancies of graduated severity

Diabetes ◽  
1985 ◽  
Vol 34 (8) ◽  
pp. 734-743 ◽  
Author(s):  
J. R. Bourbon ◽  
B. Pignol ◽  
L. Marin ◽  
M. Rieutort ◽  
C. Tordet
Keyword(s):  
Rat Lung ◽  
Fetal Rat ◽  
Fetal Rat Lung

Failure of systemic N-acetyl cysteine to protect the rat lung against bleomycin toxicity

Pathology ◽  
1987 ◽  
Vol 19 (4) ◽  
pp. 358-360 ◽  
Author(s):  
Helen E. Ward ◽  
Anthony Nicholson ◽  
Norbert Berend
Keyword(s):  
Rat Lung ◽  
Acetyl Cysteine

scholarly journals Characterizations of Pneumocystis carinii and rat lung lipids: glyceryl ethers and fatty alcohols

1998 ◽  
Vol 39 (10) ◽  
pp. 1907-1917 ◽  
Author(s):  
Edna S. Kaneshiro ◽  
Zengkui Guo ◽  
Donggeun Sul ◽  
Kathryn A. Kallam ◽  
Koka Jayasimhulu ◽  
...  
Keyword(s):  
Pneumocystis Carinii ◽  
Fatty Alcohols ◽  
Rat Lung
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