No sex difference in the urinary excretion of the histamine metabolite methylimidazoleacetic acid (MeImAA) when corrected for creatinine excretion

1999 ◽  
Vol 48 (0) ◽  
pp. 92-93 ◽  
Author(s):  
G. Granerus ◽  
B. Lönnqvist ◽  
M. Stenström <!-RID="h1"--
Keyword(s):  
Urinary Excretion ◽  
Sex Difference ◽  
Creatinine Excretion ◽  
Histamine Metabolite ◽  
Methylimidazoleacetic Acid

scholarly journals Supplemented Creatine Induces Changes in Human Metabolism of Thiocompounds and One- and Two-Carbon Units

2010 ◽  
pp. 431-442
Author(s):  
T Navrátil ◽  
E Kohlíková ◽  
M Petr ◽  
D Pelclová ◽  
M Heyrovský ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Vitamin B12 ◽  
Metabolic Pathways ◽  
Blood Levels ◽  
Redox Processes ◽  
Human Metabolism ◽  
Metabolic Disturbances ◽  
Creatinine Excretion ◽  
Thiodiglycolic Acid ◽  
The Last Man

The administration of creatine (5 g/day for one month) to 11 young active sportsmen affected their urinary excretion of creatine, creatinine, and thiodiglycolic acid (TDGA) as well as blood levels of homocysteine, vitamin B12 and folates. The probands were divided into four groups, according to the amount of creatine found in urine, and of folates and vitamin B12 determined in blood. The changes of folates and vitamin B12 were mutually reciprocal. Each group utilized CR as donor of one- and two-carbon (1C and 2C) units by means of homocysteine (HoCySH), folates, and vitamin B12, in different metabolic pathways. In 10 men the creatine administration was accompanied by an increase of HoCySH level in blood, while in the last man, with accidentally discovered hyperhomocysteinemia, the HoCySH level dropped by 50 %. Differences between initial and terminal TDGA levels indicate that creatine affects equilibria of redox processes. Creatinine excretion into urine changed in the dependence on the extent of metabolic disturbances.

scholarly journals Nitrogen balance in adult female mink (Mustela vison) in response to normal feeding andshort-term fasting

1997 ◽  
Vol 78 (1) ◽  
pp. 83-96 ◽  
Author(s):  
Anne-Helene Tauson ◽  
Jan Elnif ◽  
Søren Wamberg
Keyword(s):  
Urinary Excretion ◽  
Renal Clearance ◽  
Adult Female ◽  
Accurate Determination ◽  
Mustela Vison ◽  
Published Data ◽  
Purine Derivatives ◽  
Total N ◽  
Creatinine Excretion

Ten adult female mink (Mustela vison) were studied in a 7 d balance experiment consisting of a 2 d pre-surgery feeding period, followed by surgery, 1 d of recovery, 4 d of ad libitum feeding, and a 2d fasting period. In this experiment (Expt A) the animals had osmoticpumps implanted for continuous release of radioactively-labelled p–aminohippuric acid (p–aminobenzoyl-2-[3H]glycine; [3H]PAH;n10) and 14C-labelled inulin ([14C]IN; n 5). Repeated 24 h collections of urine, corrected to 100%[3H]PAH or [14C]IN recovery, were used for accurate determination of N balances, 24 h urinary excretion of urea, creatinine, and total N, and calculation of mean 24 h renal clearance rates for endogenous creatinine and inulin. N balances were slightly below zero, but not significantly different between feeding and fasting periods, indicating that correction to 100% [3H]PAH recovery resulted in slight overestimation of thefinal balances. During fasting, withdrawal of the dietary water and protein loads resulted in a dramatic decline in 24 h urinary volume, and urea and creatinine excretion. Large individualvariations in 24h urinary creatinine excretion (with relative variation coefficients up to 30%) confirmed that this is an unreliable index of the completeness of urine collection. In this respect, recovery rates of [3H]PAH proved far more consistent. Renal clearance values obtained in fed mink were in fair agreement with published data from cats, dogs and ferrets (Mustela putorius furo). Inulin clearance was about 30% higher than endogenous creatinine clearance, although its decline in response to fasting was not significant. In a separate study (Expt B)another ten female mink were equipped with osmotic pumps containing [3H]PAH for determination of 24 h excretion rates of purine derivatives. During feeding, allantoin accounted for more than 97 % of the excretion of purine derivatives in urine, uric acid making up less than 2·5%, xanthine and hypoxanthine less than 1 %. In fasted animals, urinary excretion of each of these purine derivatives declined to less than 50% of the feeding value. In conclusion, an experimental technique is presented for efficient and accurate measurements of daily urinary excretion of nitrogenous constituents, which allows for correct determination of N balances in adult mink and, presumably, in other mammalian species.

scholarly journals Studies on the role of taurine in Friedreich's ataxia

1984 ◽  
Vol 11 (S4) ◽  
pp. 610-615 ◽  
Author(s):  
B. Lemieux ◽  
R. Giguère ◽  
D. Shapcott
Keyword(s):  
Urinary Excretion ◽  
Muscle Mass ◽  
Friedreich’S Ataxia ◽  
Friedreich's Ataxia ◽  
Control Groups ◽  
Creatinine Excretion

AbstractNew studies were undertaken to verify the previous findings of increased urinary excretion of taurine, in the basal state and after challenge with a taurine load, in Friedreich's disease. Particular attention was paid to possible causes of error such as weight, muscle mass, creatine and creatinine excretion, variability with time and appropriate control groups. Although the overall findings were confirmed, their interpretation is open to question because of all these factors of error. Many possibilities must still be further explored to account for the apparent taurine retention defect observed in many cases of Friedreich's disease.

The Urinary Excretion of 1-Methylimidazole-4-Acetic Acid, a Histamine Metabolite, by Healthy and Asthmatic Children

1973 ◽  
Vol 45 (2) ◽  
pp. 193-198
Author(s):  
Hazel Thom ◽  
Joyce E. Richardson ◽  
R. G. Mitchell
Keyword(s):  
Acetic Acid ◽  
Urinary Excretion ◽  
Statistical Difference ◽  
Control Group ◽  
Histamine Metabolism ◽  
Restricted Diet ◽  
Asthmatic Children ◽  
Histamine Metabolite ◽  
Methylation Pathway

1. The excretion of 1-methylimidazole-4-acetic acid (MeIAA) in urine was measured in three groups of asthmatic children (acute-symptoms, quiescent and steroid-treated) and a control group of hospitalized non-asthmatic children all on the same restricted diet. 2. There was no statistical difference between the excretion of MeIAA in urine in any of the groups. There was therefore no evidence of impairment of the methylation pathway of histamine metabolism in asthma.

Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion

1990 ◽  
Vol 52 (4) ◽  
pp. 746-751 ◽  
Author(s):  
M J Pöyhönen ◽  
U M Uusitalo ◽  
A Kari ◽  
J A Takala ◽  
L A Alakuijala ◽  
...  
Keyword(s):  
Circadian Rhythm ◽  
Menstrual Cycle ◽  
Urinary Excretion ◽  
Creatinine Excretion
Sign in / Sign up

Export Citation Format

Share Document