Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

A. Avdeef; B. Testa

doi:10.1007/pl00012496

Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

Cellular and Molecular Life Sciences ◽

10.1007/pl00012496 ◽

2002 ◽

Vol 59 (10) ◽

pp. 1681-1689 ◽

Cited By ~ 106

Author(s):

A. Avdeef ◽

B. Testa

Keyword(s):

Drug Research ◽

State Of The Art ◽

The State ◽

Experimental Techniques ◽

Physicochemical Profiling

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Principles and Applications of Ceramic Humidity Sensors

Active and Passive Electronic Components ◽

10.1155/1994/91016 ◽

1994 ◽

Vol 16 (2) ◽

pp. 69-87 ◽

Cited By ~ 20

Author(s):

Mario Pelino ◽

Carlo Cantalini ◽

Marco Faccio

Keyword(s):

Impedance Spectroscopy ◽

Relative Humidity ◽

Response Time ◽

State Of The Art ◽

The State ◽

Experimental Techniques ◽

Humidity Sensors ◽

Temperature Range ◽

Si Doped ◽

Signal Response

This paper presents a brief review of the state of the art in humidity and gas ceramic sensors R&D; it also describes the principle, fabrication and application of the humidity-sensitive Si-doped a-hematite (α-Fe2O3) sintered compacts. The humidity signal response is characterized by volt-amperometric and impedance spectroscopy techniques in the 0-97% relative humidity (RH) range. The response time of the sensor is evaluated by 0-60% RH variations. Experimental techniques used to measure the hysteresis, drift, and aging of the humidity setasor are presented and the results are discussed. The CO sensitivity is investigated by activating the sensor in the 350-450℃ temperature range. A humidity-meter prototype, based on the α-Fe2O3ceramic compact is described, and its electronics and features are presented in this paper.

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Experimental Techniques in Fracture Characterization

Materials Science Forum ◽

10.4028/www.scientific.net/msf.567-568.39 ◽

2007 ◽

Vol 567-568 ◽

pp. 39-44

Author(s):

W. R. Tyson

Keyword(s):

Fracture Toughness ◽

State Of The Art ◽

Research Trends ◽

The State ◽

Experimental Techniques ◽

Fracture Characterization ◽

Girth Welds ◽

Linepipe Steel

Characterization of fracture toughness is discussed in relation to specification of steels for northern pipelines. The state of the art and research trends in measurement of CTOD for girth welds and CTOA for linepipe steel are described.

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Heterogeneous photocatalysts: an overview of classic and modern approaches for optical, electronic, and charge dynamics evaluation

Chemical Society Reviews ◽

10.1039/c8cs00882e ◽

2019 ◽

Vol 48 (5) ◽

pp. 1255-1271 ◽

Cited By ~ 61

Author(s):

Hui Ling Tan ◽

Fatwa F. Abdi ◽

Yun Hau Ng

Keyword(s):

State Of The Art ◽

The State ◽

Experimental Techniques ◽

Charge Dynamics ◽

Key Aspects

This review summarizes current experimental techniques, including the conventional and the state-of-the-art tools, to examine the key aspects of photocatalysts.

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Practical Picture Processing

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100051700 ◽

1974 ◽

Vol 32 ◽

pp. 338-339

Author(s):

T. A. Welton

Keyword(s):

Radiation Damage ◽

Coherence Length ◽

Spatial Information ◽

State Of The Art ◽

Coherent Radiation ◽

The State ◽

Energy Spread ◽

Electron Micrograph ◽

Picture Processing ◽

Molecular Skeleton

Various authors have emphasized the spatial information resident in an electron micrograph taken with adequately coherent radiation. In view of the completion of at least one such instrument, this opportunity is taken to summarize the state of the art of processing such micrographs. We use the usual symbols for the aberration coefficients, and supplement these with £ and 6 for the transverse coherence length and the fractional energy spread respectively. He also assume a weak, biologically interesting sample, with principal interest lying in the molecular skeleton remaining after obvious hydrogen loss and other radiation damage has occurred.

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