scholarly journals Rate of explosion of the Amperean area of the planar Brownian loop

1994 ◽  
pp. 153-163
Author(s):  
Wendelin Werner
Keyword(s):  
Brownian Loop

scholarly journals DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

2019 ◽  
Vol 47 (13) ◽  
pp. 6956-6972 ◽  
Author(s):  
John F Marko ◽  
Paolo De Los Rios ◽  
Alessandro Barducci ◽  
Stephan Gruber
Keyword(s):  
Protein Complexes ◽  
Molecular Motor ◽  
Strong Dependence ◽  
Extrusion Process ◽  
Chromosomal Dna ◽  
Step Size ◽  
New Class ◽  
Pull Out ◽  
Structural Maintenance Of Chromosome ◽  
Brownian Loop

AbstractCells possess remarkable control of the folding and entanglement topology of long and flexible chromosomal DNA molecules. It is thought that structural maintenance of chromosome (SMC) protein complexes play a crucial role in this, by organizing long DNAs into series of loops. Experimental data suggest that SMC complexes are able to translocate on DNA, as well as pull out lengths of DNA via a ‘loop extrusion’ process. We describe a Brownian loop-capture-ratchet model for translocation and loop extrusion based on known structural, catalytic, and DNA-binding properties of the Bacillus subtilis SMC complex. Our model provides an example of a new class of molecular motor where large conformational fluctuations of the motor ‘track’—in this case DNA—are involved in the basic translocation process. Quantitative analysis of our model leads to a series of predictions for the motor properties of SMC complexes, most strikingly a strong dependence of SMC translocation velocity and step size on tension in the DNA track that it is moving along, with ‘stalling’ occuring at subpiconewton tensions. We discuss how the same mechanism might be used by structurally related SMC complexes (Escherichia coli MukBEF and eukaryote condensin, cohesin and SMC5/6) to organize genomic DNA.

scholarly journals Decomposition of Brownian loop-soup clusters

2019 ◽  
Vol 21 (10) ◽  
pp. 3225-3253 ◽  
Author(s):  
Wei Qian ◽  
Wendelin Werner
Keyword(s):  
Brownian Loop ◽  
Brownian Loop Soup

scholarly journals Brownian Loops, Layering Fields and Imaginary Gaussian Multiplicative Chaos

2021 ◽  
Vol 381 (3) ◽  
pp. 889-945
Author(s):  
Federico Camia ◽  
Alberto Gandolfi ◽  
Giovanni Peccati ◽  
Tulasi Ram Reddy
Keyword(s):  
Random Fields ◽  
Main Tool ◽  
Nucl Phys ◽  
Vertex Operators ◽  
Chaos Expansion ◽  
Linear Functionals ◽  
Renormalization Procedure ◽  
Brownian Loop Measure ◽  
Brownian Loop ◽  
Brownian Loop Soup

AbstractWe study fields reminiscent of vertex operators built from the Brownian loop soup in the limit as the loop soup intensity tends to infinity. More precisely, following Camia et al. (Nucl Phys B 902:483–507, 2016), we take a (massless or massive) Brownian loop soup in a planar domain and assign a random sign to each loop. We then consider random fields defined by taking, at every point of the domain, the exponential of a purely imaginary constant times the sum of the signs associated to the loops that wind around that point. For domains conformally equivalent to a disk, the sum diverges logarithmically due to the small loops, but we show that a suitable renormalization procedure allows to define the fields in an appropriate Sobolev space. Subsequently, we let the intensity of the loop soup tend to infinity and prove that these vertex-like fields tend to a conformally covariant random field which can be expressed as an explicit functional of the imaginary Gaussian multiplicative chaos with covariance kernel given by the Brownian loop measure. Besides using properties of the Brownian loop soup and the Brownian loop measure, a main tool in our analysis is an explicit Wiener–Itô chaos expansion of linear functionals of vertex-like fields. Our methods apply to other variants of the model in which, for example, Brownian loops are replaced by disks.

scholarly journals Conformal correlation functions in the Brownian loop soup

2016 ◽  
Vol 902 ◽  
pp. 483-507 ◽  
Author(s):  
Federico Camia ◽  
Alberto Gandolfi ◽  
Matthew Kleban
Keyword(s):  
Correlation Functions ◽  
Brownian Loop ◽  
Brownian Loop Soup

scholarly journals Generalized disconnection exponents

2020 ◽  
Author(s):  
Wei Qian
Keyword(s):  
Physical Interpretation ◽  
Acta Math ◽  
General Version ◽  
Multiple Points ◽  
New Family ◽  
The Family ◽  
Definition Of ◽  
Open Question ◽  
Brownian Loop ◽  
Critical Intensity

Abstract We introduce and compute the generalized disconnection exponents$$\eta _\kappa (\beta )$$ η κ ( β ) which depend on $$\kappa \in (0,4]$$ κ ∈ ( 0 , 4 ] and another real parameter $$\beta $$ β , extending the Brownian disconnection exponents (corresponding to $$\kappa =8/3$$ κ = 8 / 3 ) computed by Lawler, Schramm and Werner (Acta Math 187(2):275–308, 2001; Acta Math 189(2):179–201, 2002) [conjectured by Duplantier and Kwon (Phys Rev Lett 61:2514–2517, 1988)]. For $$\kappa \in (8/3,4]$$ κ ∈ ( 8 / 3 , 4 ] , the generalized disconnection exponents have a physical interpretation in terms of planar Brownian loop-soups with intensity $$c\in (0,1]$$ c ∈ ( 0 , 1 ] , which allows us to obtain the first prediction of the dimension of multiple points on the cluster boundaries of these loop-soups. In particular, according to our prediction, the dimension of double points on the cluster boundaries is strictly positive for $$c\in (0,1)$$ c ∈ ( 0 , 1 ) and equal to zero for the critical intensity $$c=1$$ c = 1 , leading to an interesting open question of whether such points exist for the critical loop-soup. Our definition of the exponents is based on a certain general version of radial restriction measures that we construct and study. As an important tool, we introduce a new family of radial SLEs depending on $$\kappa $$ κ and two additional parameters $$\mu , \nu $$ μ , ν , that we call radial hypergeometric SLEs. This is a natural but substantial extension of the family of radial $$\hbox {SLE}_\kappa (\rho )s$$ SLE κ ( ρ ) s .

The Brownian loop soup

2004 ◽  
Vol 128 (4) ◽  
pp. 565-588 ◽  
Author(s):  
Gregory F. Lawler ◽  
Wendelin Werner
Keyword(s):  
Brownian Loop ◽  
Brownian Loop Soup
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