Effect of Lipids on the Stability of Natural Rubber Latex and Tensile Properties of its Films

2017 ◽  
Vol 20 (4) ◽  
pp. 213-222 ◽  
Author(s):  
H. Yu ◽  
Q. Wang ◽  
J. Li ◽  
Y. Liu ◽  
D. He ◽  
...  
2013 ◽  
Vol 747 ◽  
pp. 103-106 ◽  
Author(s):  
Prapaporn Boonme ◽  
Hasleena Boontawee ◽  
Wirach Taweepreda ◽  
Wiwat Pichayakorn

The mucous liquid of Hevea brasiliensis or Para rubber tree, called natural rubber latex (NRL), composes of cis-1,4-polyisoprene which can form a patch under suitable formulation. In this study, blank and 5% lidocaine-loaded NRL patches were formulated and then characterized for physicochemical properties as well as evaluated in vitro drug release and stability. The patches were observed for their appearances. Surface morphology of the patches was investigated using a SEM. XRD was employed to study the crystallinity of the drug, the patch, and the drug-loaded patch. The extractions of lidocaine-loaded patches were analyzed for drug contents by HPLC. In vitro drug release study was performed using modified Franz diffusion cells. The patches at initial preparation and after kept at 4, 25, and 45 °C for 3 months were investigated for the stability determination. The results suggested that NRL could be used as a main component in pharmaceutical transdermal patches with acceptable physicochemical properties. Lidocaine-loaded NRL patches provided desirable drug release but high storage temperatures could age the patches resulting in darken color and lower release amount.


2013 ◽  
Vol 858 ◽  
pp. 46-51 ◽  
Author(s):  
Mufidah Md Sidek ◽  
A. Rashid Azura ◽  
Baharin Azahari

The effect of different types and loading of cleaning agent on the tensile properties and swelling properties of natural rubber latex film were investigated. The aim for this study is to find the cleaning agent which is compatible with natural rubber latex with optimum loading. In this study, there are two different amine based cleaning agent used which are Monoethanolamine (MEA) and Di-(3-aminopropyl) ether of diethylene glycol (DG). Swelling test was done to support the tensile results. It is found that tensile properties of the sample with MEA cleaning agent is higher than control sample (without cleaning agent) and sample with DG cleaning agent. For the best cleaning agent compound, the different loading has been tested and results showed that optimum loading of cleaning agent are achieved at 5 phr. The effects of both types of cleaning agents and different loading of cleaning agents on tensile properties and swelling properties for cleaning mold application are discuss.


2012 ◽  
Vol 09 (17) ◽  
pp. 38-41
Author(s):  
Hugo David CHIRINOS ◽  
Sueli CARVALHO DE JESUS

Natural rubber latex is a dispersion of natural rubber particles in water. These particles are coated with a protein layer which will stabilize the dispersion in water by forming an electric charge in the layer. Any different condition affecting this layer disturbs the stability of dispersion. Microorganism attack disturbs the protein layer and consequently the stability of the dispersion. By adding 1.2% by weight of NH3, the stability of the dispersion can be improved. The fresh latex was irradiated by Co-60 with irradiation dose of 10, 20, 30, 40 and 100 kGy. The results showed a relationship between the volatile fatty acid content (VFA, product from microorganism attack on carbohydrate) and the green strength or the physical properties of vulcanized film. Low VFA number showing a higher physical strength of the film either un-vulcanized or vulcanized. It appeared that the structure was responsible in yielding a good physical property of the film.


2014 ◽  
Vol 42 (3) ◽  
pp. 20130069
Author(s):  
Matthew R. Schwerin ◽  
Donna L. Walsh ◽  
Zhiwei Zhang

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