Bitter taste threshold and its relation to number of circumvallate papillae in the elderly

1999 ◽  
Vol 11 (1) ◽  
pp. 61-63 ◽  
Author(s):  
A. Mavi ◽  
O. Ceyhan
Keyword(s):  
Bitter Taste ◽  
The Elderly ◽  
Taste Threshold ◽  
Circumvallate Papillae

Investigations on taste blindness with thiocarbamides II (1). Intra-pair discrepancy of taste in pairs of identical twins

1959 ◽  
Vol 8 (3) ◽  
pp. 361-368 ◽  
Author(s):  
P. E. Verkade ◽  
B. M. Wepster ◽  
L. J. Stegerhoek
Keyword(s):  
Bitter Taste ◽  
Threshold Concentration ◽  
Identical Twins ◽  
The Other ◽  
Taste Threshold ◽  
Frequency Curve ◽  
Hereditary Property ◽  
Wrong Side ◽  
The World

SUMMARYDuring the World Twin Congress held at Eindhoven (Netherlands) in 1957 we tested 70 pairs of identical twins for their ability to taste para-ethoxyphenylthiocarbamide (EPTC). In 2 pairs a clear intra-pair discrepancy of taste was encountered. The tests with these 2 pairs were continued weekly for about six months. The result was always the same. One member of the pair found a bitter taste even in a solution 1:320,000 of EPTC; the other member considered even a solution 1:5,000 of this compound, i.e. a solution of the «taste blindness threshold concentration», completely tasteless. The former is a «taster», the latter is a «non-taster».A similar intra-pair discrepancy in taste with regard to phenylthiocarbamide (PTC) in pairs of identical twins has been found by Ardashnikov c.s. and by Rife.The ability to taste certain thiocarbamides without doubt being a hereditary property, the discrepancy of taste found must have an exogenic cause, the nature of which is unknown.The fact in question is discussed on the basis of the well-established bimodality of the taste threshold concentration/frequency curve for thiocarbamides. It is pointed out that the «non-tasters» of the pairs of identical twins under consideration must be regarded as «crypto tasters». Their taste threshold concentration lies on the «wrong» side of the (more or less arbitrarily adopted) «taste blindness threshold concentration» (1:5,000 for EPTC and PTC).The consequences of the existence of «crypto tasters» and also «crypto non-tasters» for work in the field of genetics with the aid of appropriate thiocarbamides are briefly indicated.

scholarly journals Bitter taste threshold and bronchial obstruction in bronchial asthma

2017 ◽  
Vol 95 (9) ◽  
pp. 843-846
Author(s):  
Valerii N. Mineev ◽  
I. Yu. Supranovich ◽  
A. A. Kuzikova
Keyword(s):  
Healthy Volunteers ◽  
Potassium Chloride ◽  
Allergic Asthma ◽  
Bronchial Asthma ◽  
Negative Correlation ◽  
Bitter Taste ◽  
Significant Negative Correlation ◽  
Taste Sensitivity ◽  
Bronchial Obstruction ◽  
Taste Threshold

Aim. To compare bitter taste sensitivity to potassium chloride and parameters of bronchial patency in patients with bronchial asthma (BSA). Material and methods. The study involved 40 healthy volunteers, 82 patients with allergic asthma (ABA), 48 patients with non-allergic asthma (NABA). Spirometry was conducted. The method of Robert I.Henkin et al. (1963) was used to determine the threshold of taste sensitivity to the bitter taste (potassium chloride). Results. The bitter taste threshold was significantly higher in asthmatic patients, particularly in patients with allergic variant of the disease compared to healthy volunteers. Statistically significant inverse correlations were revealed between bitter taste threshold and those volume (VC: τ=-0,306; n=43, p<0,01) and speed parameters (FEV1: τ=-0,429; n=44, p<0,01; MEF50: τ=-0,419; n=43, p<0,01; MEF75: τ=-0,460; n=44, p<0,01) that were obtained after inhalation of β2-agonist (berotec). Moreover, negative correlation (τ=-0,221, n=56, p<0,01) was documented between bitter taste threshold and blood ionized calcium level. Non-allergic BA was characterized by significant negative correlation between bitter taste threshold and initial vital capacity. Conclusion. The above findings suggest that changes in bitter taste sensitivity and disorders of bronchial patency in allergic BA may have common pathogenetic mechanisms based in accordance with modern concepts on disturbances in signal transduction systems coupled to G-proteins.

Positive association between bitter taste threshold and preference of vegetables among adolescents

2020 ◽  
Author(s):  
Mathias Hald ◽  
Minna Onat Hald ◽  
Jelena Stankovic ◽  
Andreas Steenholt Niklassen ◽  
Therese Ovesen
Keyword(s):  
Bitter Taste ◽  
Positive Association ◽  
Taste Threshold

scholarly journals Association between smell and taste dysfunction and obesity and metabolic syndrome in older adults

2021 ◽  
Vol 4 (4) ◽  
pp. 210-217
Author(s):  
S.S. Dobrow ◽  
J.J. Qazi ◽  
S.C. Payne ◽  
J.L. Mattos
Keyword(s):  
Metabolic Syndrome ◽  
Regression Models ◽  
Bitter Taste ◽  
Multivariate Analyses ◽  
The Elderly ◽  
Logistic Regression Models ◽  
Health And Nutrition ◽  
Salty Taste ◽  
Taste Dysfunction ◽  
Negative Health Outcomes

Background: Obesity and metabolic syndrome (MS) are prevalent and associated with negative health outcomes in the elderly. There is a need to identify risk factors for these diseases in this population. Methodology: The 2013-14 National Health and Nutrition Examination Survey was used in this study. Adults aged 60 or under were categorized into normosmia, hyposmia, anosmia, and combined anosmia + hyposmia using the Pocket Sniff Test. Taste was evaluated using quinine and NaCl solutions. Multivariate logistic regression models were used to characterize associations between smell and taste status and obesity and MS. Results: In univariate obesity analysis, normosmia, combined anosmia + hyposmia, and 0.32M NaCl taste dysfunction were significant. 0.32M NaCl taste dysfunction remained significant in multivariate analysis. MS was significantly associated with only tongue tip quinine dysfunction in univariate and multivariate analyses. Conclusions: Salty taste dysfunction was found to be negatively associated with obesity while bitter taste dysfunction was found to be positively associated with MS.

scholarly journals Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae

Neuroscience ◽  
2018 ◽  
Vol 369 ◽  
pp. 29-39 ◽  
Author(s):  
Ryusuke Yoshida ◽  
Shingo Takai ◽  
Keisuke Sanematsu ◽  
Robert F. Margolskee ◽  
Noriatsu Shigemura ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Taste Cells ◽  
Circumvallate Papillae

Some Observations on Changes in Denervated Taste Buds of Circumvallate Papillae of Rabbits

1969 ◽  
Vol 27 ◽  
pp. 308-309
Author(s):  
Sunao Fujimoto ◽  
Raymond G. Murray ◽  
Assia Murray
Keyword(s):  
Taste Buds ◽  
Taste Bud ◽  
Cell Type ◽  
Dark Cells ◽  
Type Iii ◽  
Circumvallate Papillae ◽  
Taste Bud Cells ◽  
Light Cells

Taste bud cells in circumvallate papillae of rabbit have been classified into three groups: dark cells; light cells; and type III cells. Unilateral section of the 9th nerve distal to the petrosal ganglion was performed in 18 animals, and changes of each cell type in the denervated buds were observed from 6 hours to 10 days after the operation.Degeneration of nerves is evident at 12 hours (Fig. 1) and by 2 days, nerves are completely lacking in the buds. Invasion by leucocytes into the buds is remarkable from 6 to 12 hours but then decreases. Their extrusion through the pore is seen. Shrinkage and disturbance in arrangement of cells in the buds can be seen at 2 days. Degenerated buds consisting of a few irregular cells and remnants of degenerated cells are present at 4 days, but buds apparently normal except for the loss of nerve elements are still present at 6 days.

Cell surface changes during aging of human bladder epithelium examined by lectin probes and SEM

1990 ◽  
Vol 48 (3) ◽  
pp. 966-967
Author(s):  
J. Jacob ◽  
M.F.M. Ismail
Keyword(s):  
The Elderly ◽  
Ultrastructural Changes ◽  
Pokeweed Mitogen ◽  
Asymmetric Structure ◽  
Luminal Surface ◽  
Bladder Epithelium ◽  
Aldehyde Groups ◽  
Cell Surface Changes ◽  
Phosphate Buffered Saline ◽  
Surface Changes

Ultrastructural changes have been shown to occur in the urinary bladder epithelium (urothelium) during the life span of humans. With increasing age, the luminal surface becomes more flexible and develops simple microvilli-like processes. Furthermore, the specialised asymmetric structure of the luminal plasma membrane is relatively more prominent in the young than in the elderly. The nature of the changes at the luminal surface is now explored by lectin-mediated adsorption visualised by scanning electron microscopy (SEM).Samples of young adult (21-31 y old) and elderly (58-82 y old) urothelia were fixed in buffered 2% glutaraldehyde for 10 m and washed with phosphate buffered saline (PBS) containing Ca++ and Mg++ at room temperature. They were incubated overnight at 4°C in 0.1 M ammonium chloride in PBS to block any remaining aldehyde groups. The samples were then allowed to stand in PBS at 37°C for 2 h before incubation at 37°C for 30 m with lectins. The lectins used were concanavalin A (Con A), wheat germ agglutinin (WGA), phytohaemagglutinin (PHA) and pokeweed mitogen (PWM) at a concentration of 500 mg/ml in PBS at pH 7.A.

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