Serum FSH bioactivity and inhibin levels in patients with gonadotropin secreting and nonfunctioning pituitary adenomas

1998 ◽  
Vol 21 (6) ◽  
pp. 372-379 ◽  
Author(s):  
S. Borgato ◽  
L. Persani ◽  
R. Romoli ◽  
D. Cortelazzi ◽  
A. Spada ◽  
...  
2013 ◽  
Author(s):  
Apostolos Karagiannis ◽  
Dimitrios Boufas ◽  
Konstantinos Tzioras ◽  
Andreas Seretis ◽  
Andromachi Vryonidou

2008 ◽  
Vol 70 (5) ◽  
pp. 1325-1329 ◽  
Author(s):  
Bruce E. Pollock ◽  
Joseph Cochran ◽  
Neena Natt ◽  
Paul D. Brown ◽  
Dana Erickson ◽  
...  

2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P48-P48
Author(s):  
Fabio Ferreli ◽  
Mario Turri-Zanoni ◽  
Stefania Gallo ◽  
Maurizio Bignami ◽  
Giustino Tomei ◽  
...  

2015 ◽  
Vol 100 (8) ◽  
pp. 3132-3139 ◽  
Author(s):  
N. C. van Varsseveld ◽  
C. C. van Bunderen ◽  
A. A. M. Franken ◽  
H. P. F. Koppeschaar ◽  
A. J. van der Lely ◽  
...  

2011 ◽  
Vol 55 (4) ◽  
pp. 266-271 ◽  
Author(s):  
Rogerio Silicani Ribeiro ◽  
Julio Abucham

OBJETIVE: To evaluate the effect of clomiphene in men with hypogonadism and conventionally treated nonfunctioning pituitary adenomas (NFPA). PATIENTS AND METHODS: Open label, single-arm, prospective trial. Nine hypogonadal men (testosterone < 300 ng/dL and low/normal LH) with previously treated NFPA. Clomiphene (50 mg/day orally) for 12 weeks. Testosterone, estradiol, LH, FSH, prolactin and erectile function were evaluated before and after 10 days, 4, 8 and 12 weeks of clomiphene treatment. RESULTS: After clomiphene treatment, testosterone and erectile function improved in only one patient. In the remaining eight patients, testosterone levels decreased whereas LH, FSH, and estradiol remained unchanged. Insulin sensitivity increased in unresponsive patients. CONCLUSIONS: Compared with hypogonadal men with prolactinomas under dopaminergic therapy, clomiphene treatment failed to restore normal testosterone levels in most patients with conventionally treated NFPA.


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