Cerebrospinal fluid estrone in pseudotumor cerebri: A change in cerebral steroid hormone metabolism?

1991 ◽  
Vol 14 (2) ◽  
pp. 81-86 ◽  
Author(s):  
V. Toscano ◽  
G. Sancesario ◽  
P. Bianchi ◽  
C. Cicardi ◽  
D. Casilli ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Steroid Hormone ◽  
Pseudotumor Cerebri ◽  
Hormone Metabolism

STEROID HORMONE METABOLISM IN RESPONSIVE TISSUES IN VITRO

1971 ◽  
Vol 68 (1_Suppl) ◽  
pp. S279-S294 ◽  
Author(s):  
Paul Robel
Keyword(s):  
Steroid Hormone ◽  
Physiological Activity ◽  
Physiological State ◽  
Target Cells ◽  
Target Tissue ◽  
Hormone Metabolism ◽  
Metabolizing Enzymes ◽  
Relationship Of

ABSTRACT Of the information available on steroid hormone metabolism in responsive tissues, only that relating hormone metabolism to physiological activity is reviewed, i. e. metabolite activity in isolated in vitro systems, binding of metabolites to target tissue receptors, specific steroid hormone metabolizing enzymes and relationship of hormone metabolism to target organ physiological state. Further, evidence is presented in the androgen field, demonstrating 5α-reduced metabolites, formed inside the target cells, as active compounds. This has led to a consideration of testosterone as a »prehormone«. The possibility that similar events take place in tissues responding to progesterone is discussed. Finally, the role of hormone metabolism in the regulation of hormone availability and/or renewal in target cells is discussed. In this context, reference is made to the potential role of plasma binding proteins and cytosol receptors.

DRUG-INDUCED ALTERATIONS OF STEROID HORMONE METABOLISM IN MAN

1973 ◽  
Vol 212 (1 Multienzyme S) ◽  
pp. 148-155 ◽  
Author(s):  
H. Leon Bradlow ◽  
Barnett Zumoff ◽  
D. K. Fukushima ◽  
Leon Hellman ◽  
David R. Bickers ◽  
...  
Keyword(s):  
Steroid Hormone ◽  
Hormone Metabolism ◽  
Drug Induced

Involvement of the H-2 Complex in Steroid Hormone Metabolism

H-2 Antigens ◽  
1987 ◽  
pp. 125-132
Author(s):  
Marika Pla ◽  
Anna Rocca ◽  
Daniel Gillet ◽  
Jean-Marie Villette ◽  
Jean Fiet ◽  
...  
Keyword(s):  
Steroid Hormone ◽  
Hormone Metabolism

The Adrenal Lipid Droplet is a New Site for Steroid Hormone Metabolism

PROTEOMICS ◽  
2018 ◽  
Vol 18 (23) ◽  
pp. 1800136 ◽  
Author(s):  
Jinhai Yu ◽  
Linqiang Zhang ◽  
Yunhai Li ◽  
Xiaotong Zhu ◽  
Shimeng Xu ◽  
...  
Keyword(s):  
Lipid Droplet ◽  
Steroid Hormone ◽  
Hormone Metabolism

Effects of Diet or Liming on Steroid Hormone Metabolism and Reproduction in Atlantic Salmon (Salmo salar) Held in an Acidic River

1990 ◽  
Vol 47 (12) ◽  
pp. 2422-2430 ◽  
Author(s):  
G. B. Sangalang ◽  
H. C. Freeman ◽  
J. F. Uthe ◽  
L. S. Sperry
Keyword(s):  
Atlantic Salmon ◽  
Salmo Salar ◽  
Reproductive Performance ◽  
Steroid Hormone ◽  
Control Fish ◽  
Dietary Salt ◽  
Hormone Metabolism ◽  
Atlantic Salmon Salmo Salar ◽  
Water Ph ◽  
Acidic River

Attempts to avert the impacts of an acidic river environment on Atlantic salmon (Salmo salar) were carried out in 1985 and 1986. Salmon were held in the Westfield River (pH 4.7–5.2) and the nearby Medway River (pH 5.3–5.6) during their sexual maturation. A diet containing 3% NaCl was fed to the Westfield salmon in 1985. Marble chips were used to elevate the pH of Westfield River water in 1986. Fish fed the salt diet had higher peak levels of plasma sex hormones, higher fecundity, greater incidence of spawners, lower egg mortality, and less weight loss than fish fed a commercial trout diet. The reproductive performance of fish held in limed water (pH 5.1–5.9) almost attained the level observed in the Medway (control) fish. Limestone treatment stimulated early peaking of blood androgen levels, testosterone, and 11-ketotestosterone in Westfield males, and 17α, 20β-dihydroxy-4-pregnen-3-one, a follicular mediator of gonadotropin, in a few Westfield females. The head kidneys produced more cortisol and corticosterone in all Westfield fish in both years compared to Medway fish. The results suggest that neither dietary salt nor liming completely prevented the decline of reproductive performance and the alteration of steroid hormone metabolism in salmon.

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