In the rat, estrone sulphate is the main serum metabolite of oral oleoyl-estrone

2007 ◽  
Vol 30 (5) ◽  
pp. 376-381 ◽  
Author(s):  
C. Cabot ◽  
D. González-Martínez ◽  
J. A. Fernández-López ◽  
M. Alemany
Keyword(s):  
Estrone Sulphate

In vitro uptake of labeled estrone, estradiol and estrone sulphate in the endometrium and myometrium of human perfused uterus

1986 ◽  
Vol 25 ◽  
pp. 116
Author(s):  
C Bulletti ◽  
VM Jasonni ◽  
P Ciotti ◽  
S Tabanelli ◽  
C. Flamigni
Keyword(s):  
Estrone Sulphate ◽  
In Vitro Uptake

The effect of tamoxifen on the function and lifespan of the corpus luteum and on subsequent ovarian function

1989 ◽  
Vol 121 (3) ◽  
pp. 417-425 ◽  
Author(s):  
M. L. Swahn ◽  
M. Bygdeman ◽  
S. A. Matlin ◽  
Z. Y. Wu
Keyword(s):  
Corpus Luteum ◽  
Ovarian Function ◽  
Treatment Cycle ◽  
Bleeding Pattern ◽  
Secretory Phase ◽  
Luteal Function ◽  
Menstrual Cycles ◽  
17 Hydroxyprogesterone ◽  
Estrone Sulphate

Abstract. The aim of the present study was to investigate the effects of tamoxifen on pituitary and luteal function and on the bleeding pattern when administered continuously in the secretory phase. The study included 16 women with regular menstrual cycles followed during one control, one treatment and one follow-up cycle. Each volunteer received 20 mg tamoxifen twice daily from cycle day 18 to menstruation in the treatment cycle. The luteal phase was slightly, but significantly prolonged during treatment, and FSH, progesterone, 17-hydroxyprogesterone, 20α-dihydro progesterone, estrone, estrone sulphate and estradiol significantly elevated in comparison with corresponding data during the control cycle. The results indicate that estrogen may be of some importance for the regulation of the life span of the corpus luteum in the human. The significantly elevated levels of pregnanediol glucuronide and estrone glucuronide during the follow-up cycle are most likely a result of either a direct effect of remaining circulating tamoxifen levels on the ovary, or mediated through the increased release of FSH. If estrogens are of importance for the process of implantation, which has recently been suggested in subhuman primates, also in the human remains unclear. Studies on the effect of anti-estrogens on the endometrium during the secretory phase of the cycle are ongoing.

Treatment with oral estrone sulphate in the female climacteric: I. Influence on lipids

1981 ◽  
Vol 60 (1) ◽  
pp. 27-31 ◽  
Author(s):  
A. Lagrelius ◽  
P. Johnson ◽  
N. O. Lunell ◽  
G. Samsioe
Keyword(s):  
Estrone Sulphate

scholarly journals Estimating Insemination Time in Mares on the Basis of the Urinary Concentration of Estrone-Sulphate.

1998 ◽  
Vol 9 (4) ◽  
pp. 125-127 ◽  
Author(s):  
Ruby Mojica SILVA ◽  
Yui TAKEYAMA ◽  
Tomas Javier ACOSTA AYALA ◽  
Missaka Priyadarsana Bandara WIJAYAGUNAWARDANE ◽  
Ana Yimiko KOJIMA ◽  
...  
Keyword(s):  
Urinary Concentration ◽  
Estrone Sulphate

scholarly journals Accurate prediction of birth implementing a statistical model through the determination of steroid hormones in saliva

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Silvia Alonso ◽  
Sara Cáceres ◽  
Daniel Vélez ◽  
Luis Sanz ◽  
Gema Silvan ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Area Under The Curve ◽  
Machine Learning Algorithms ◽  
Random Forest Model ◽  
Forest Model ◽  
Spontaneous Labour ◽  
Hormonal Mechanism ◽  
First Time ◽  
Estrone Sulphate

AbstractSteroidal hormone interaction in pregnancy is crucial for adequate fetal evolution and preparation for childbirth and extrauterine life. Estrone sulphate, estriol, progesterone and cortisol play important roles in the initiation of labour mechanism at the start of contractions and cervical effacement. However, their interaction remains uncertain. Although several studies regarding the hormonal mechanism of labour have been reported, the prediction of date of birth remains a challenge. In this study, we present for the first time machine learning algorithms for the prediction of whether spontaneous labour will occur from week 37 onwards. Estrone sulphate, estriol, progesterone and cortisol were analysed in saliva samples collected from 106 pregnant women since week 34 by enzyme-immunoassay (EIA) techniques. We compared a random forest model with a traditional logistic regression over a dataset constructed with the values observed of these measures. We observed that the results, evaluated in terms of accuracy and area under the curve (AUC) metrics, are sensibly better in the random forest model. For this reason, we consider that machine learning methods contribute in an important way to the obstetric practice.

scholarly journals Longitudinal study on steroid hormone variations during the second trimester of gestation: a useful tool to confirm adequate foetal development

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Silvia Alonso ◽  
Sara Caceres ◽  
Daniel Vélez ◽  
Luis Sanz ◽  
Gema Silvan ◽  
...  
Keyword(s):  
Well Being ◽  
Second Trimester ◽  
Sample Collection ◽  
Foetal Development ◽  
Non Invasive ◽  
Physiological Processes ◽  
Normal Ranges ◽  
Highly Sensitive ◽  
Invasive Method ◽  
Estrone Sulphate

Abstract Background The interaction of hormonal factors are crucial for good foetal development. During the second trimester of gestation, most of the main physiological processes of foetal development occur. Therefore, the aim of this study was to determine the variations in the physiological levels of cortisol, estriol, estrone sulphate, and progesterone during the second trimester (weeks 12–26) in order to establish normal ranges that can serve as indicators of foetal well-being and good functioning of the foetal-placental unit. Methods Saliva samples from 106 pregnant women were collected weekly (from week 12 to week 26 of gestation), and hormonal measurements were assayed by an enzyme immunoassay. The technique used for hormone measurements was highly sensitive and served as a non-invasive method for sample collection. Results The results revealed a statistically significant (p<0.05) difference between cortisol, progesterone, and oestrogens throughout the second trimester, with a more substantial relationship between oestrogens and progesterone [P4-E3 (r=0.427); P4-E1SO4 (r=0.419)]. By analysing these hormone concentrations, statistically significant (p<0.05) elevations in progesterone, cortisol, and estriol levels were found at the 16th [(P4 (0.78±0.088), C(1.99±0.116), E3(2.513±0.114)]; 18th [(P4 (1.116±0.144), C(3.409±0.137), E3(3.043±0.123)] and 23rd week of gestation [(P4(1.36±0.153), C(1.936±0.11), E3(2.657±0.07)]. Estrone sulphate levels appeared to increase progressively throughout the second trimester [from 1.103±0.03 to 2.244±0.09]. Conclusion The 18th week of gestation seems to constitute a very important week during foetal adrenal development, and the analysis of the main hormones involved in foetal development, provided more precise information regarding the proper functioning of the foetal unit and foetal development.

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