Immobilization effects on contractile properties of aging rat skeletal muscle

1998 ◽  
Vol 10 (1) ◽  
pp. 59-66 ◽  
Author(s):  
J. S. Fisher ◽  
M. Brown
Keyword(s):  
Skeletal Muscle ◽  
Contractile Properties ◽  
Rat Skeletal Muscle ◽  
Aging Rat

Early‐onset calorie restriction conserves fiber number in aging rat skeletal muscle

2004 ◽  
Vol 18 (3) ◽  
pp. 580-581 ◽  
Author(s):  
Susan McKiernan ◽  
Entela Bua ◽  
Jennifer McGorray ◽  
Judd Aiken
Keyword(s):  
Skeletal Muscle ◽  
Calorie Restriction ◽  
Early Onset ◽  
Rat Skeletal Muscle ◽  
Aging Rat ◽  
Fiber Number

scholarly journals Metabolomic profiling of aging rat skeletal muscle

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Sean M. Garvey ◽  
Lining Guo ◽  
Adam D. Kennedy ◽  
Jonathan E. McDunn ◽  
Suzette L. Pereira
Keyword(s):  
Skeletal Muscle ◽  
Rat Skeletal Muscle ◽  
Metabolomic Profiling ◽  
Aging Rat

Temperature-dependent physiological stability of rat skeletal muscle in vitro

1985 ◽  
Vol 248 (3) ◽  
pp. C265-C270 ◽  
Author(s):  
S. S. Segal ◽  
J. A. Faulkner
Keyword(s):  
Skeletal Muscle ◽  
Incubation Temperature ◽  
Muscle Thickness ◽  
Bath Temperature ◽  
Contractile Properties ◽  
Sprague Dawley ◽  
Rat Skeletal Muscle ◽  
Tension Development ◽  
Incubation Temperatures

Stability of rat skeletal muscle contractile properties with time in vitro as a function of incubation temperature was characterized. Female Sprague-Dawley rats (8 wk, 148 g) were anesthetized with pentobarbital sodium (40 mg/kg, ip). Intact soleus (SOL) and extensor digitorum longus (EDL) muscles of 70- to 90-mg mass were removed and studied at incubation temperatures of 20, 25, 30, 35, and 40 degrees C. The average muscle thickness was 2.0 mm. Each muscle was studied at one temperature only. At 5, 15, 30, 45, and 60 min following immersion in an oxygenated Krebs-Ringer bicarbonate solution, isometric contractile properties were measured. Peak twitch tension, maximum tetanic tension, and rate of tension development of both SOL and EDL muscles were stable with time at 20 and 25 degrees C but decreased with time as a function of bath temperature above 25 degrees C. The calculated critical radius for O2 diffusion declined from 1.19 mm at 20 degrees C to 0.51 mm at 40 degrees C. For SOL and EDL muscles incubated at 25 degrees C, the histochemical demonstration of glycogen content was similar to that of fresh muscles, whereas muscles incubated at 40 degrees C showed staining for glycogen only in peripheral fibers. Observed and calculated results both infer a progressively larger hypoxic core at incubation temperatures above 25 degrees C.

997 THE EFFECTS OF GLUCOCORTICOIDS ON THE CONTRACTILE PROPERTIES OF RAT SKELETAL MUSCLE IN SITU

1993 ◽  
Vol 25 (Supplement) ◽  
pp. S177
Author(s):  
I. S. Vrabas ◽  
S. L. Dodd ◽  
J. M. Eason ◽  
S. K. Powers
Keyword(s):  
Skeletal Muscle ◽  
Contractile Properties ◽  
Rat Skeletal Muscle
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