THE ANTIBIOTIC TREATMENT OF BACTERIAL MENINGITIS IS LOOKING UP

InPharma ◽  
1981 ◽  
Vol 312 (1) ◽  
pp. 17-18
Keyword(s):  
Bacterial Meningitis ◽  
Antibiotic Treatment

Antibiotic Treatment—Much Better than Nothing

2019 ◽  
pp. 135-154
Author(s):  
Janet R. Gilsdorf
Keyword(s):  
Clinical Trials ◽  
Bacterial Meningitis ◽  
Antibiotic Treatment ◽  
Animal Experiments ◽  
Effective Management ◽  
Basic Principles ◽  
Duration Of Therapy ◽  
The Past ◽  
Drug Doses ◽  
Better Than

Over the past five decades, many animal experiments as well as clinical trials of antibiotics in humans treated for meningitis have defined the levels of antibiotics that are present in infected meninges and in the blood, thus informing the drug doses necessary to successfully treat the infection. In spite of the different kinds of bacteria that cause meningitis and the availability of various antibiotics to treat it, several basic principles of effective management for all common forms of bacterial meningitis have emerged from the decades of research. As a result of these studies, most children with meningitis in America receive appropriate antibiotic treatment (the correct antibiotic and the correct dose for the correct duration of therapy), and their outcomes are much, much better than the disastrous outcomes of earlier eras.

Bacterial meningitis antibiotic treatment

2017 ◽  
Vol 24 (12) ◽  
pp. S42-S45 ◽  
Author(s):  
R. Cohen ◽  
J. Raymond ◽  
L. Hees ◽  
D. Pinquier ◽  
E. Grimprel ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Antibiotic Treatment

scholarly journals Pediatric Bacterial Meningitis Prognosis and Antibiotic Treatment

2011 ◽  
Vol 85 (2) ◽  
pp. 150-154 ◽  
Author(s):  
Hiroshi SAKATA ◽  
Keisuke SUNAKAWA ◽  
Masato NONOYAMA ◽  
Yoshitake SATO ◽  
Tsunekazu HARUTA ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Antibiotic Treatment

Antibiotic treatment delay and outcome in acute bacterial meningitis

2008 ◽  
Vol 57 (6) ◽  
pp. 449-454 ◽  
Author(s):  
Rasmus Køster-Rasmussen ◽  
André Korshin ◽  
Christian N. Meyer
Keyword(s):  
Bacterial Meningitis ◽  
Antibiotic Treatment ◽  
Treatment Delay ◽  
Acute Bacterial Meningitis

ANTIBIOTIC TREATMENT IN BACTERIAL MENINGITIS

The Lancet ◽  
1989 ◽  
Vol 334 (8664) ◽  
pp. 685-686
Author(s):  
I.K. Mecrow ◽  
T.G. Powell ◽  
Heikki Peltola ◽  
Marja Anttila ◽  
Olli-Veikko Renkonen
Keyword(s):  
Bacterial Meningitis ◽  
Antibiotic Treatment

scholarly journals Delays in diagnosis and treatment of vaccine preventable community acquired bacterial meningitis (CABM): a retrospective analysis at three tertiary care centers

2020 ◽  
Author(s):  
Sarah D Torres ◽  
Mitashee Das ◽  
Carla Y Kim ◽  
Jyoti V Ankam ◽  
Nicole Luche ◽  
...  
Keyword(s):  
New York ◽  
Bacterial Meningitis ◽  
Median Time ◽  
Antibiotic Treatment ◽  
Medical Center ◽  
Tertiary Care ◽  
Case Series ◽  
Diagnosis And Treatment ◽  
Haemophilus Influenzae Type ◽  
Delays In Diagnosis

Abstract Background Outcomes in community-acquired bacterial meningitis (CABM) are significantly impacted by delays in diagnosis and treatment. This retrospective case series aims to describe the sociodemographic, epidemiological, and clinical variables including time to diagnosis and treatment of vaccine preventable CABM in three tertiary care settings in New York City (NYC). Methods A retrospective chart review was conducted of patients at Columbia University Irving Medical Center (CUIMC), Children’s Hospital of New York (CHONY), Mount Sinai Health System, and Weill Cornell Medical Center with CABM due to Haemophilus influenzae type B, Streptococcus pneumoniae, and Neisseria meningitidis between January 1, 2012 and December 31, 2017. A descriptive statistical analysis was performed. Results Our case series consisted of 36 patients, 24 (66.7%) females, and 12 (33.33%) males with a median age of 42 years (IQR 55 years). Median time from presentation to lumbar puncture (LP) was eight hours (IQR 7). The median time from hospital presentation to diagnosis was 12 hours (IQR 9), and the median time from LP to diagnosis was three hours (IQR 5). Delay in diagnosis which is defined by more than 8 hours from hospital presentation, occurred in 13 patients (36.1%) due to initial misdiagnosis, most commonly systemic febrile and/or viral infections and otitis media. Conclusions Despite evidence of the importance of early diagnosis and treatment for CABM, this case series shows the ongoing challenges with early clinical diagnosis. Misdiagnoses were an underlying reason for delays from presentation to LP and to antibiotic treatment in the majority of our patients. This study in NYC identifies ongoing major delays in diagnosis and antimicrobial treatment in CABM, and future studies are needed to identify mechanisms to improve time to antibiotic treatment and LP in CABM.

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