Butoconazole nitrate: 1% and 2% creams compare well with miconazole nitrate in vaginal candidiasis

InPharma ◽  
1985 ◽  
Vol 508 (1) ◽  
pp. 6-6
Keyword(s):  
Vaginal Candidiasis ◽  
Miconazole Nitrate ◽  
Butoconazole Nitrate

scholarly journals Effect of Butoconazole Nitrate 2% Vaginal Cream and Miconazole Nitrate 2% Vaginal Cream Treatments in Patients with Vulvovaginal Candidiasis

1996 ◽  
Vol 4 (6) ◽  
pp. 323-328
Author(s):  
Myra A. Lappin ◽  
Doris C. Brooker ◽  
Carol A. Francisco ◽  
Joan Dorfman
Keyword(s):  
Potassium Hydroxide ◽  
Signs And Symptoms ◽  
Vulvovaginal Candidiasis ◽  
Vaginal Cream ◽  
Miconazole Nitrate ◽  
Symptom Scores ◽  
Cure Rates ◽  
Lost To Follow Up ◽  
Butoconazole Nitrate

In a multicenter, randomized, invesgtigator-blind, parallel study, 398 patients were dispensed topical butoconazole nitrate 2% cream for 3 days (n = 199) or miconazole nitrate 2% cream for 7 days (n = 199) for vaginal use. Efficacy analyses included 254 patients with culture-confirmedCandida(119 butoconazole and 135 miconazole users). Of the 398 patients issued study medication, 9 were lost to follow-up. Therefore, safety analyses included 389 patients (197 butoconazole and 192 miconazole users). Evaluations upon admission and approximately 8 and 30 days post-treatment includedCandidacultures, potassium hydroxide (KOH) wet mounts, and vulvovaginal examinations, with rating of vulvovaginal signs and symptoms using a 4-point scale. Rates of clinical cure (based on sign/symptom scores), microbiologic cure (based on cultures and wet mounts), and therapeutic cure (both clinical and microbiologic cures) were assessed and were to be similar between the regimens. Therapeutic cure rates were 57.8% and 61.4% for butoconazole and miconazole, respectively. Three-day butoconazole treatment was as safe and effective as 7-day miconazole therapy in treating vulvovaginal candidiasis.

Miconazole Nitrate-loaded Microparticles For Buccal Use: Immediate Drug Release and Antifungal Effect

2017 ◽  
Vol 14 (8) ◽  
Author(s):  
Andres Felipe Cartagena ◽  
Amanda Martinez Lyra ◽  
Aline Cristina Kapuchczinski ◽  
Amanda Migliorini Urban ◽  
Luis Antonio Esmerino ◽  
...  
Keyword(s):  
Drug Release ◽  
Antifungal Effect ◽  
Miconazole Nitrate

Lactobacilli Reduce Recurrences of Vaginal Candidiasis in Pregnant Women: A Randomized, Double‐Blind, Placebo‐Controlled Study

2021 ◽  
Author(s):  
Xin‐Yee Ang ◽  
Fiona‐Yi‐Li Chung ◽  
Boon‐Kiat Lee ◽  
Siti Nur Afiqah Azhar ◽  
Salina Sany ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Vaginal Candidiasis ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo
Sign in / Sign up

Export Citation Format

Share Document