COPING WITH BENZODIAZEPINE WITHDRAWAL SYMPTOMS

InPharma ◽  
1981 ◽  
Vol 281 (1) ◽  
pp. 11-11
Keyword(s):  
Withdrawal Symptoms ◽  
Benzodiazepine Withdrawal

Benzodiazepine withdrawal symptoms and propranolol

1982 ◽  
Vol 2 (2) ◽  
pp. 152
Author(s):  
Peter Tyrer ◽  
David Rutherford ◽  
Tony Huggett
Keyword(s):  
Withdrawal Symptoms ◽  
Benzodiazepine Withdrawal

A Controlled Trial of Dothiepin and Placebo in Treating Benzodiazepine Withdrawal Symptoms

1996 ◽  
Vol 168 (4) ◽  
pp. 457-461 ◽  
Author(s):  
Peter Tyrer ◽  
Brian Ferguson ◽  
Cosmo Hallström ◽  
Marian Michie ◽  
Stephen Tyrer ◽  
...  
Keyword(s):  
Tricyclic Antidepressants ◽  
Drug Withdrawal ◽  
Controlled Trial ◽  
Statistical Significance ◽  
Withdrawal Symptoms ◽  
Antidepressant Effect ◽  
Double Blind ◽  
Benzodiazepine Dependence ◽  
Benzodiazepine Withdrawal ◽  
To Receive

BackgroundThe possibility that treatment with tricyclic antidepressants, in the form of dothiepin, might attenuate benzodiazepine withdrawal symptoms was investigated in a double-blind trial.MethodEighty-seven non-depressed psychiatric out-patients with putative normal dose benzodiazepine dependence had their benzodiazepines reduced in stepwise amounts of 20% of the original dose for eight weeks. The patients were randomised to receive dothiepin (with dosage increasing to 150 mg/day) or placebo as an aid to withdrawal before benzodiazepine reduction and these drugs were taken for four further weeks before being stopped.ResultsFewer patients entered and completed the study than expected and a Type II error was possible in the results. Although there was some evidence of withdrawal symptoms being less marked in those patients allocated to dothiepin this was independent of any antidepressant effect as depression scores were lower in the placebo group in the early phase of withdrawal (P<0.01). Of those completing the study, greater satisfaction (P=0.03) was recorded by those who had received dothiepin; no other differences reached statistical significance.ConclusionsDothiepin (and by implication other tricyclic antidepressants) might have some value in reducing benzodiazepine withdrawal symptoms but does not aid drug withdrawal.

A new scale for the evaluation of benzodiazepine withdrawal symptoms: Sessb

1994 ◽  
Vol 55 (3) ◽  
pp. 275-289 ◽  
Author(s):  
G.B. Cassano ◽  
A. Petracca ◽  
B.M. Cesana
Keyword(s):  
Withdrawal Symptoms ◽  
Benzodiazepine Withdrawal

Benzodiazepine Withdrawal Symptoms

1980 ◽  
Vol 137 (6) ◽  
pp. 750-c-751 ◽  
Author(s):  
SEYMOUR R. KAPLAN
Keyword(s):  
Withdrawal Symptoms ◽  
Benzodiazepine Withdrawal

Frequency of self-reported ‘anxiolytic withdrawal’ symptoms in a group of female students experiencing anxiety

1986 ◽  
Vol 16 (2) ◽  
pp. 467-472 ◽  
Author(s):  
E. K. Rodrigo ◽  
P. Williams
Keyword(s):  
Female Students ◽  
Withdrawal Symptoms ◽  
Benzodiazepine Withdrawal ◽  
Withdrawal Syndromes ◽  
Taste And Smell

SynopsisThis study describes the occurrence of self-reported perceptual phenomena in students experiencing anxiety. Phenomena like hypersensitivity to touch, hyposensitivity to taste and smell, and unusual tastes and smells appear to be non-specific and to be closely related to the level of anxiety. They emphasize the need for the development of techniques to elicit perceptual phenomena, and to investigate their occurrence and the intensity of their phenomena in variously defined groups. These also have implications for the assessment of benzodiazepine withdrawal syndromes.

Patient treatment insistence and medication craving in long-term low-dosage benzodiazepine prescriptions

1998 ◽  
Vol 28 (3) ◽  
pp. 721-729 ◽  
Author(s):  
M. LINDEN ◽  
T. BÄR ◽  
B. GEISELMANN
Keyword(s):  
Drug Holiday ◽  
Withdrawal Symptoms ◽  
Patient Treatment ◽  
Real Form ◽  
Factors Associated ◽  
Withdrawal Treatment ◽  
Benzodiazepine Withdrawal ◽  
Long Acting ◽  
Low Dosage

Background. Long-term low-dosage dependence on benzodiazepines is traditionally explained by withdrawal symptoms. Previous research has not given much attention to reports that suggest that many patients oppose stopping benzodiazepines long before withdrawal symptoms have developed. This study investigates the scope of and factors associated with this pre-withdrawal treatment insistence.Methods. Patients receiving long-term low-dosage benzodiazepines in primary care were asked to take a drug-holiday of at least 3 weeks. Sociodemographic, medication, morbidity and attitudinal variables were assessed in addition to the GPs' perceptions of their patients.Results. Two-thirds of the patients rejected the drug-holiday proposal. Patients who refused a drug-holiday were less educated and were using a higher percentage of long-acting benzodiazepines than patients who accepted the drug-holiday proposal. Those who refused were seen by their GPs as being more complaining, harder to satisfy and less co-operative.Conclusions. These results provide evidence for drug-seeking or craving behaviour of patients who receive low-dosage benzodiazepine prescriptions. A major problem in benzodiazepine withdrawal occurs before the withdrawal programme has even begun. These data show that benzodiazepine low-dosage dependence should be considered a real form of dependence.

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