Surfactant TA: reduces infant deaths in hyaline membrane disease

InPharma ◽  
1987 ◽  
Vol 582 (1) ◽  
pp. 4-5
Author(s):  
Rajesh B. Patel ◽  
Hinal A. Sinol ◽  
Sonal V. Jindal ◽  
Jayendra R. Gohil

Background: Infant deaths from Bhavnagar rural areas were studied by using a verbal autopsy tool.Methods: Community visit based retrospective study of Bhavnagar rural by WHO verbal autopsy questionnaire.Results: Of the 92 deaths analyzed, 59 % (early), 12% (late), and 29% were during the post neonatal period. Male deaths were 55 (60%). The most common immediate causes were infection (39%), birth asphyxia (23%), and hyaline membrane disease (15%). Underlying causes were: maternal illness with feeding problem (45%), prematurity (26%), meconium aspiration syndrome (9%), and congenital/genetic anomalies (10%). Infant and neonatal deaths were seen more with illiteracy of mother, age of mother (25-29 years), third parity, anemia, and vaginal discharge; and non-breastfed, low birth weight and preterm. Birth asphyxia and hyaline membrane disease were during early, and meningitis and pneumonia were after the neonatal period. Verbal autopsy was accurate in 18/23 (78%) of the facility-based deaths where the cause of death was available. Ethics approval was obtained.Conclusions: Reproductive health education to adolescent girls and mothers, regarding the treatment of fever, vaginal discharge; and breastfeeding counselling with vitamin B12 should be used as more infant deaths are associated with anemia of mother. Health workers should be skilled in neonatal resuscitation, prematurity management, and referral, after stabilization, identification of congenital anomaly, antenatal screening by USG, and neonatal metabolic screen. Recent 2018 data obtained from Bhavnagar District Health Authority shows that over a period of eight years, institutional deliveries have increased and home deliveries, early neonatal deaths, HMD, and septicemia have decreased. Perinatal care should be check-list based, monitored, and mentored.


2020 ◽  
Author(s):  
Rajesh Patel ◽  
Jayendra Ratilal Gohil

Background: Infant deaths from Bhavnagar rural areas were studied by using a verbal autopsy tool. Method: Community visit based retrospective study of Bhavnagar rural by WHO verbal autopsy questionnaire. Results: Of the 92 deaths analyzed, 59 % (early), 12% (late), and 29% were during the post Neonatal period. Male deaths were 55 (60%). The most common immediate causes were infection (39%), birth asphyxia (23%), hyaline membrane disease (15%). Underlying causes were: maternal illness with feeding problem (45%), prematurity (26%), meconium aspiration syndrome (9%), and congenital/ genetic anomalies (10%). Infant and neonatal deaths were seen more with illiteracy of mother, age of mother (25-29 y), third parity, anemia, and vaginal discharge; and non-breastfed, low birth weight and preterm. Birth Asphyxia and hyaline membrane disease were associated with early, and meningitis and pneumonia with a postneonatal period. Verbal Autopsy was accurate in 18/ 23 (78%) facility-based deaths where the cause of death was available. Conclusion: Reproductive health education to adolescent girls and mothers, regarding the treatment of fever, vaginal discharge; and breastfeeding counseling. Vitamin B12 should be used as more infant deaths are associated with anemia of mother. Health workers should be skilled in neonatal resuscitation, prematurity management, and early referral, identification of congenital anomaly, an inborn error of metabolism, antenatal screening by USG, and Neonatal metabolic screen. Recent 2018 data obtained from Bhavnagar District Health Authority shows that over a period of eight years, institutional deliveries have increased and home deliveries, early neonatal deaths, HMD, and septicemia have decreased.


2017 ◽  
Vol 38 (3-4) ◽  
pp. 47
Author(s):  
Lasmida Nazir Nuriman ◽  
Dadang Sjarif Hidajat

There have been controversies over the eiTect of hypertension in pregnancy on the incidence of type I neonatal respiratory distress syndrome or hyaline membrane disease (HMD). We investigated the relationship between the incidence of HMD and maternal hypertension during pregnancy in 91 infants at 34 weeks gestation or less. This retrospective cross sectional study included all live born babies between May 1, 1994 and April 30, 1995 at Dr. Hasan Sadikin General Hospital, Bandung. Maternal hypertension during pregnancy was diagnosed in 38 mothers of91 infants studied. The incidence of HMD (5%) in the maternal hypertension during pregnancy group was significantly lower than the 62% in the normotensive group (p<0.01). There was a negative correlation between the occurence of HMD and hypertension during pregnancy. We conclude that the risk of developing HMD in infants born to hypertensive mothers is significantly lower than those born to normotensive mothers.


1957 ◽  
Vol 51 (6) ◽  
pp. 726-741 ◽  
Author(s):  
Paul Curtis

Neonatology ◽  
1985 ◽  
Vol 47 (6) ◽  
pp. 317-322 ◽  
Author(s):  
I. Sen ◽  
T. Tulassay ◽  
J. Kiszel ◽  
F. Ruppert ◽  
E. Sulyok ◽  
...  

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