PERSISTENT SKIN ATROPHY AFTER TRIAMCINOLONE INJECTION

InPharma ◽  
1979 ◽  
Vol 196 (1) ◽  
pp. 8-8
Keyword(s):  
Skin Atrophy ◽  
Triamcinolone Injection

Kindler's Syndrome with Recurrent Neutropenia: Report of Two Cases from Saudi Arabia

2020 ◽  
Author(s):  
Yousef Binamer ◽  
Muzamil A. Chisti
Keyword(s):  
Autosomal Recessive ◽  
Common Mechanism ◽  
Sequencing Analysis ◽  
Loss Of Function ◽  
Skin Atrophy ◽  
Whole Exome ◽  
Infancy And Childhood ◽  
Genetics And Genomics ◽  
New Feature ◽  
Generation Sequencing

AbstractKindler syndrome (KS) is a rare photosensitivity disorder with autosomal recessive mode of inheritance. It is characterized by acral blistering in infancy and childhood, progressive poikiloderma, skin atrophy, abnormal photosensitivity, and gingival fragility. Besides these major features, many minor presentations have also been reported in the literature. We are reporting two cases with atypical features of the syndrome and a new feature of recurrent neutropenia. Whole exome sequencing analysis was done using next-generation sequencing which detected a homozygous loss-of-function (LOF) variant of FERMT1 in both patients. The variant is classified as a pathogenic variant as per the American College of Medical Genetics and Genomics guidelines. Homozygous LOF variants of FERMT1 are a common mechanism of KS and as such confirm the diagnosis of KS in our patients even though the presentation was atypical.

Less is more when treating the nasal ala with superficial radiotherapy

2020 ◽  
Vol 7 (3) ◽  
pp. 66-69
Author(s):  
Lucy M Butcher ◽  
Gerald B Fogarty ◽  
Susan Sinclair ◽  
Hanna Kuchel ◽  
Robert Paver
Keyword(s):  
Functional Outcomes ◽  
Skin Atrophy ◽  
Functional Importance ◽  
Less Is More ◽  
Skin Cancers ◽  
Nasal Ala ◽  
Cosmetic Outcomes ◽  
Standard Fractionation ◽  
Comparative Trials ◽  
Common Malignancy

Skin cancer is the most common malignancy, is increasing in incidence, and occurs most commonly on the head and neck. Cancers of the nasal ala pose therapeutic challenges given the cosmetic and functional importance. Both surgery and radiotherapy (RT) have similar oncological outcomes. RT is tissue-conserving and may have an advantage in cosmetic and functional outcomes, but more comparative trials are needed. RT needs to be delivered well to avoid late effects such as skin atrophy, fibrosis and telangiectasia, which may increase with higher dose per fraction. We describe three cases of self-reported thinning of the nasal ala following definitive mildly hypofractionated superficial radiotherapy (SXRT) of 2.5 Gy per fraction. SXRT to skin cancers of the nasal alar with standard fractionation of at most 2 Gy per fraction may be important in ensuring excellent cosmetic outcomes and patient satisfaction.

Surgical Answer to Intralesional Steroid–Induced Skin Atrophy

2017 ◽  
Vol 43 (4) ◽  
pp. 591-592 ◽  
Author(s):  
Karalikkattil T. Ashique ◽  
Feroze Kaliyadan
Keyword(s):  
Skin Atrophy ◽  
Intralesional Steroid

Ocular Syphilis Unmasked Following Intravitreal Triamcinolone Injection

2009 ◽  
Vol 17 (3) ◽  
pp. 213-215 ◽  
Author(s):  
Bushra Mushtaq ◽  
Rajen Gupta ◽  
Samer Elsherbiny ◽  
Philip I. Murray
Keyword(s):  
Intravitreal Triamcinolone ◽  
Ocular Syphilis ◽  
Triamcinolone Injection ◽  
Intravitreal Triamcinolone Injection
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