EFFECT OF METHYLDOPA ON SERUM PROLACTIN AND GROWTH HORMONE LEVELS

InPharma ◽  
1976 ◽  
Vol 38 (1) ◽  
pp. 15-15
1983 ◽  
Vol 34 (1) ◽  
pp. 74-78 ◽  
Author(s):  
Carlo Ferrari ◽  
Cristiano Barbieri ◽  
Roberto Caldara ◽  
Pietro Rampini ◽  
Alessandra Paracchi ◽  
...  

1972 ◽  
Vol 70 (2) ◽  
pp. 373-384 ◽  
Author(s):  
W. N. Spellacy ◽  
W. C. Buhi ◽  
S. A. Birk

ABSTRACT Seventy-one women were treated with a daily dose of 0.25 mg of the progestogen ethynodiol diacetate. They were all tested with a three-hour oral glucose tolerance test before beginning the steroid and then again during the sixth month of use. Measurements were made of blood glucose and plasma insulin and growth hormone levels. There was a significant elevation of the blood glucose levels after steroid treatment as well as a deterioration in the tolerance curve in 12.9% of the women. The plasma insulin values were also elevated after drug treatment whereas the fasting ambulatory growth hormone levels did not significantly change. There was a significant association between the changes in glucose and insulin levels and the subject's age, control weight, or weight gain during treatment. The importance of considering the metabolic effects of the progestogen component of oral contraceptives is stressed.


Diabetes ◽  
1976 ◽  
Vol 25 (3) ◽  
pp. 167-172 ◽  
Author(s):  
R. Vigneri ◽  
S. Squatrito ◽  
V. Pezzino ◽  
S. Filetti ◽  
S. Branca ◽  
...  

2008 ◽  
Vol 12 (3-4) ◽  
pp. 294-306
Author(s):  
J. HILLMAN ◽  
J. HAMMOND ◽  
J. SOKOLA ◽  
M. REISS

PEDIATRICS ◽  
1971 ◽  
Vol 48 (6) ◽  
pp. 998-999
Author(s):  
S. H. Reisner ◽  
M. Cornblath ◽  
Ronald W. Gotlin

In the article by J. R. Humbert and R. W. Gotlin,1 the authors state that previous reports in which hypoglycemia was induced artificially with insulin demonstrated a variable growth hormone response. They then refer to the paper by Cornblath, et al.2 as reporting a failure to obtain a rise in growth hormone levels. This is incorrect as we found that insulin-induced hypoglycemia actually resulted in a very marked rise in growth hormone levels in both the full-term and premature infants tested.


2020 ◽  
Author(s):  
Marcin Adamczak ◽  
Piotr Kuczera ◽  
Andrzej Wiecek

Kidneys play the major role in the synthesis and degradation of several hormones. Different coexisting conditions such as inflammation, malnutrition and metabolic acidosis and applied treatment may also cause endocrine abnormalities in chronic kidney disease (CKD) patients. A tendency towards decreased thyroxin and triiodothyronine with normal serum concentrations of reversed triiodothyronine (as opposed to other chronic non-thyroid, non-kidney diseases) and thyroid stimulating hormone are observed. As far as the somatotopic axis is concerned, in CKD normal serum concentration of growth hormone and its effector – the insulin-like growth factor are observed. Nevertheless, due to the phenomenon of GH/IGF-1 “resistance” CKD patients usually present a phenotype resembling GH deficiency. Serum prolactin concentrations are often elevated in CKD women and men. This leads to the dysregulation of the pituitary-gonadal axis causing hypogonadism and it’s clinical consequences regardless of patient’s gender. The alterations in hormones of gonadal origin caused by uremia, together with hyperprolactinemia lead to the development of sexual dysfunction and infertility in men and women. The alterations of thyroid, pituitary gland and gonads associated with CKD are discussed in this chapter. This review contains 4 tables, and 64 references. Keywords: chronic kidney disease, hypothyroidism, hyperthyroidism, growth hormone, recombinant human GH, insulin-like growth factors, hemodialysis


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