Fluoxetine cost effective for psychiatric disorders in India

2003 ◽  
Vol 395 (1) ◽  
pp. 5-5
Author(s):  
Shilpa Suresh Bisen ◽  
Yogesh Deshpande

In the era of digital technology, the internet has its significant role in sprouting vulnerability toward the different form of addictions and psychiatric disorders as well as providing the platform to manage them effectively. The internet provides ready access to illicit drugs, nonprescription medications which facilitate a sale of controlled substances over the Internet without a valid prescription which contributed to the rise of several forms of addictions. Studies have linked the severity of Problematic Internet Use to increase chances of substance Use disorder. Utilization of internet for longer durations serves as a booster for behavioral addictions like online gambling. Web based interventions on the positive side provides a cost effective, readily accessible and user-friendly platform to reach out majority of patients to help them in seeking treatment of Addictions and various psychiatric disorders. The aim of this chapter is to discuss the contribution of the internet in a positive and negative way to develop as well as resolve Psychiatric disorder.


2017 ◽  
Vol 41 (S1) ◽  
pp. S92-S93
Author(s):  
D. Scuticchio ◽  
M.O. Bertelli ◽  
G. Chiodelli ◽  
R. Cavagnola ◽  
F. Manna

IntroductionDespite increasing awareness of high prevalence of psychiatric disorders in people with intellectual disability (ID), diagnostic tools are few and scarcely used in daily practice. SPAID-G (psychiatric instrument for the intellectually disabled adult-general version) is the first Italian for carrying out psychiatric diagnostic orientations in adults with ID. It was designed to be easy and quick instrument for daily clinical practice.Objectives/AimsThe present study was aimed at evaluating psychometric and psychodiagnostic characteristics of the SPAID-G and at supplying new data on the prevalence rate of psychiatric disorders in a multicentric Italian sample of people with ID living in different settings.MethodsThe SPAID-G was consecutively administered to more than 800 persons with ID attending residential, rehabilitative or clinical services across Italy. A part of the sample was also assessed for psychopathology through the use of DASH-II, PDD-MRS and clinically diagnosed in accordance to DSM-IV-TR and DSM-5 criteria.ResultsSPAID internal consistency, inter-rater reliability and concordance with DASH-II and PDD-MRS resulted to be good. Around 40% of the sample was assessed to have a cluster of psychopathological symptoms that could be consistent with a psychiatric diagnosis. Autism, impulse control disorder and personality disorder resulted to be the most frequent over threshold scores.ConclusionsThe SPAID-G seems to be a valid and cost-effective screening tool for the psychiatric assessment within the Italian population with ID.Disclosure of interestThe authors have not supplied their declaration of competing interest.


10.2196/10078 ◽  
2018 ◽  
Vol 5 (3) ◽  
pp. e10078 ◽  
Author(s):  
Alan R Teo ◽  
Samuel BL Liebow ◽  
Benjamin Chan ◽  
Steven K Dobscha ◽  
Amanda L Graham

Background Younger military veterans are at high risk for psychiatric disorders and suicide. Reaching and engaging veterans in mental health care and research is challenging. Social media platforms may be an effective channel to connect with veterans. Objective This study tested the effectiveness of Facebook advertisements in reaching and recruiting Iraq and Afghanistan-era military veterans in a research study focused on mental health. Methods Facebook ads requesting participation in an online health survey ran for six weeks in 2017. Ads varied imagery and headlines. Validated instruments were used to screen for psychiatric disorders and suicidality. Outcomes included impressions, click-through rate, survey completion, and cost per survey completed. Results Advertisements produced 827,918 impressions, 9,527 clicks, and 587 survey completions. Lack of enrollment in Veterans Affairs health care (193/587, 33%) and positive screens for current mental health problems were common, including posttraumatic stress disorder (266/585, 45%), problematic drinking (243/584, 42%), major depression (164/586, 28%), and suicidality (132/585, 23%). Approximately half of the survey participants (285/587, 49%) were recruited with just 2 of the 15 ads, which showed soldiers marching tied to an “incentive” or “sharing” headline. These 2 ads were also the most cost-effective, at US $4.88 and US $5.90 per participant, respectively. Among veterans with current suicidal ideation, the survey-taking image resulted in higher survey completion than the soldiers marching image (P=.007). Conclusions Facebook advertisements are effective in rapidly and inexpensively reaching military veterans, including those at risk for mental health problems and suicidality, and those not receiving Veterans Affairs health care. Advertisement image and headlines may help optimize the effectiveness of advertisements for specific subgroups.


2018 ◽  
Author(s):  
Alan R Teo ◽  
Samuel BL Liebow ◽  
Benjamin Chan ◽  
Steven K Dobscha ◽  
Amanda L Graham

BACKGROUND Younger military veterans are at high risk for psychiatric disorders and suicide. Reaching and engaging veterans in mental health care and research is challenging. Social media platforms may be an effective channel to connect with veterans. OBJECTIVE This study tested the effectiveness of Facebook advertisements in reaching and recruiting Iraq and Afghanistan-era military veterans in a research study focused on mental health. METHODS Facebook ads requesting participation in an online health survey ran for six weeks in 2017. Ads varied imagery and headlines. Validated instruments were used to screen for psychiatric disorders and suicidality. Outcomes included impressions, click-through rate, survey completion, and cost per survey completed. RESULTS Advertisements produced 827,918 impressions, 9,527 clicks, and 587 survey completions. Lack of enrollment in Veteran Affairs health care (193/587, 33%) and positive screens for current mental health problems were common, including posttraumatic stress disorder (266/585, 45%), and problematic drinking (243/584, 42%), major depression (164/586, 28%), and suicidality (132/585, 23%). Approximately half of the survey participants (285/587, 49%) were recruited with just 2 of the 15 ads, which showed soldiers marching tied to an “incentive” or “sharing” headline. These 2 ads were also the most cost-effective, at US $4.88 and US $5.90 per participant, respectively. Among veterans with current suicidal ideation, the survey-taking image resulted in higher survey completion than the soldiers marching image (P=0.007). CONCLUSIONS Facebook advertisements are effective in rapidly and inexpensively reaching military veterans, including those at risk for mental health problems and suicidality, and those not receiving Veteran Affairs health care. Advertisement image and headlines may help the effectiveness of advertisements for specific subgroups.


2018 ◽  
Vol 42 (1) ◽  
pp. 19-23
Author(s):  
Samr Dawood ◽  
Norman Poole ◽  
Robert Fung ◽  
Niruj Agrawal

Aims and methodPsychiatric disorders are common in neurological in-patients, but they are under-recognised and undertreated. We investigated the frequency of detection of mental disorder and referral to psychiatric services in a regional neuroscience centre. The results were compared with the expected prevalence. All in-patient referrals received in 2014 from the in-patient wards of the regional neuroscience centre and acute neurological unit were reviewed.ResultsA total of 129 ward referrals were identified; of these, 78 were from the regional in-patient neurological unit, which comprised 11.4% of the total of 679 admissions to that unit.Clinical implicationsA spectrum of neuropsychiatric conditions were recognised by neurologists, but overall rates of recognition were low. To address the problem of under-recognition, routine screening with validated assessment tools can represent a cost-effective and acceptable method to detect psychiatric disorders in an in-patient neurological setting.Declaration of InterestNone.


2016 ◽  
Author(s):  
Hon-Cheong So ◽  
Carlos K.L. Chau ◽  
Wan-To Chiu ◽  
Kin-Sang Ho ◽  
Cho-Pong Lo ◽  
...  

AbstractOur knowledge of disease genetics has advanced rapidly during the past decade, with the advent of high-throughput genotyping technologies such as genome-wide association studies (GWAS). However, few methodologies were developed and systemic studies performed to identify novel drug candidates utilizing GWAS data. In this study we focus on drug repositioning, which is a cost-effective approach to shorten the developmental process of new therapies. We proposed a novel framework of drug repositioning by comparing GWAS-imputed transcriptome with drug expression profiles from the Connectivity Map. The approach was applied to 7 psychiatric disorders. We discovered a number of novel repositioning candidates, many of which are supported by preclinical or clinical evidence. We found that the predicted drugs are significantly enriched for known psychiatric medications, or therapies considered in clinical trials. For example, drugs repurposed for schizophrenia are strongly enriched for antipsychotics (p = 4.69E-06), while those repurposed for bipolar disorder are enriched for antipsychotics (p = 2.26E-07) and antidepressants (p = 1.17E-05). These findings provide support to the usefulness of GWAS signals in guiding drug discoveries and the validity of our approach in drug repositioning. We also present manually curated lists of top repositioning candidates for each disorder, which we believe will serve as a useful resource for researchers.


Author(s):  
Shilpa Suresh Bisen ◽  
Yogesh Deshpande

In the era of digital technology, the internet has its significant role in sprouting vulnerability toward the different form of addictions and psychiatric disorders as well as providing the platform to manage them effectively. The internet provides ready access to illicit drugs, nonprescription medications which facilitate a sale of controlled substances over the Internet without a valid prescription which contributed to the rise of several forms of addictions. Studies have linked the severity of Problematic Internet Use to increase chances of substance Use disorder. Utilization of internet for longer durations serves as a booster for behavioral addictions like online gambling. Web based interventions on the positive side provides a cost effective, readily accessible and user-friendly platform to reach out majority of patients to help them in seeking treatment of Addictions and various psychiatric disorders. The aim of this chapter is to discuss the contribution of the internet in a positive and negative way to develop as well as resolve Psychiatric disorder.


2019 ◽  
Vol 42 ◽  
Author(s):  
Hanna M. van Loo ◽  
Jan-Willem Romeijn

AbstractNetwork models block reductionism about psychiatric disorders only if models are interpreted in a realist manner – that is, taken to represent “what psychiatric disorders really are.” A flexible and more instrumentalist view of models is needed to improve our understanding of the heterogeneity and multifactorial character of psychiatric disorders.


Author(s):  
Lawrence M. Roth

The female reproductive tract may be the site of a wide variety of benign and malignant tumors, as well as non-neoplastic tumor-like conditions, most of which can be diagnosed by light microscopic examination including special stains and more recently immunoperoxidase techniques. Nevertheless there are situations where ultrastructural examination can contribute substantially to an accurate and specific diagnosis. It is my opinion that electron microscopy can be of greatest benefit and is most cost effective when applied in conjunction with other methodologies. Thus, I have developed an approach which has proved useful for me and may have benefit for others. In cases where it is deemed of potential value, glutaraldehyde-fixed material is obtained at the time of frozen section or otherwise at operation. Coordination with the gynecologic oncologist is required in the latter situation. This material is processed and blocked and is available if a future need arises.


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