Temozolomide improves QOL in anaplastic astrocytoma

2001 ◽  
Vol 313 (1) ◽  
pp. 11-11
Keyword(s):  
Anaplastic Astrocytoma

scholarly journals Nasal‐alar invasive cutaneous aspergillosis in a patient with anaplastic astrocytoma: A case report

2021 ◽  
Author(s):  
Adham A. Aljariri ◽  
Ahmed Shaikh ◽  
Abdulqadir J. Nashwan ◽  
Mahir A. Petkar ◽  
Shanmugam Ganesan
Keyword(s):  
Case Report ◽  
Anaplastic Astrocytoma

scholarly journals T2 mapping of the peritumoral infiltration zone of glioblastoma and anaplastic astrocytoma

2021 ◽  
pp. 197140092198932
Author(s):  
Timo Alexander Auer ◽  
Maike Kern ◽  
Uli Fehrenbach ◽  
Yasemin Tanyldizi ◽  
Martin Misch ◽  
...  
Keyword(s):  
Relaxation Time ◽  
Isocitrate Dehydrogenase ◽  
Anaplastic Astrocytoma ◽  
T2 Mapping ◽  
Relaxation Times ◽  
Region Of Interest ◽  
World Health ◽  
High Grade ◽  
High Grade Gliomas ◽  
Health Organization

Purpose To characterise peritumoral zones in glioblastoma and anaplastic astrocytoma evaluating T2 values using T2 mapping sequences. Materials and methods In this study, 41 patients with histopathologically confirmed World Health Organization high grade gliomas and preoperative magnetic resonance imaging examinations were retrospectively identified and enrolled. High grade gliomas were differentiated: (a) by grade, glioblastoma versus anaplastic astrocytoma; and (b) by isocitrate dehydrogenase mutational state, mutated versus wildtype. T2 map relaxation times were assessed from the tumour centre to peritumoral zones by means of a region of interest and calculated pixelwise by using a fit model. Results Significant differences between T2 values evaluated from the tumour centre to the peritumoral zone were found between glioblastoma and anaplastic astrocytoma, showing a higher decrease in signal intensity (T2 value) from tumour centre to periphery for glioblastoma ( P = 0.0049 – fit-model: glioblastoma –25.02± 19.89 (–54–10); anaplastic astrocytoma –5.57±22.94 (–51–47)). Similar results were found when the cohort was subdivided by their isocitrate dehydrogenase profile, showing an increased drawdown from tumour centre to periphery for wildtype in comparison to mutated isocitrate dehydrogenase ( P = 0.0430 – fit model: isocitrate dehydrogenase wildtype –10.35±16.20 (–51) – 0; isocitrate dehydrogenase mutated 12.14±21.24 (–15–47)). A strong statistical proof for both subgroup analyses ( P = 0.9987 – glioblastoma R2 0.93±0.08; anaplastic astrocytoma R2 0.94±0.15) was found. Conclusion Peritumoral T2 mapping relaxation time tissue behaviour of glioblastoma differs from anaplastic astrocytoma. Significant differences in T2 values, using T2 mapping relaxation time, were found between glioblastoma and anaplastic astrocytoma, capturing the tumour centre to the peritumoral zone. A similar curve progression from tumour centre to peritumoral zone was found for isocitrate dehydrogenase wildtype high grade gliomas in comparison to isocitrate dehydrogenase mutated high grade gliomas. This finding is in accordance with the biologically more aggressive behaviour of isocitrate dehydrogenase wildtype in comparison to isocitrate dehydrogenase mutated high grade gliomas. These results emphasize the potential of mapping techniques to reflect the tissue composition of high grade gliomas.

scholarly journals Fibrosarcoma Arising in Anaplastic Astrocytoma of the Brain

1977 ◽  
Vol 17pt2 (5) ◽  
pp. 391-397
Author(s):  
SADAO NAKAJO ◽  
MASAO MURAKAMI ◽  
HIROSHI FUKAI ◽  
SADAAKI OKAMOTO ◽  
TERUO SHIRABE
Keyword(s):  
Anaplastic Astrocytoma ◽  
The Brain

scholarly journals The Mystery of Multiple Masses: A Case of Anaplastic Astrocytoma

Cureus ◽  
2017 ◽  
Author(s):  
Pooja Sethi ◽  
Jennifer Treece ◽  
Vandana Pai ◽  
Chidinma Onweni ◽  
Zia Rahman ◽  
...  
Keyword(s):  
Anaplastic Astrocytoma

scholarly journals Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma

Cancer ◽  
2008 ◽  
Vol 112 (9) ◽  
pp. 2038-2045 ◽  
Author(s):  
Marc C. Chamberlain ◽  
Denice D. Wei-Tsao ◽  
Deborah T. Blumenthal ◽  
Michael J. Glantz
Keyword(s):  
Anaplastic Astrocytoma ◽  
Salvage Chemotherapy ◽  
Temozolomide Refractory

scholarly journals The genetic landscape of anaplastic astrocytoma

Oncotarget ◽  
2013 ◽  
Vol 5 (6) ◽  
pp. 1452-1457 ◽  
Author(s):  
Patrick J. Killela ◽  
Christopher J. Pirozzi ◽  
Zachary J. Reitman ◽  
Sian Jones ◽  
B. Ahmed Rasheed ◽  
...  
Keyword(s):  
Anaplastic Astrocytoma ◽  
Genetic Landscape

The conditional probabilities of survival in patients with anaplastic astrocytoma or glioblastoma multiforme

2003 ◽  
Vol 60 (5) ◽  
pp. 402-406 ◽  
Author(s):  
C.L Lin ◽  
A.S Lieu ◽  
K.S Lee ◽  
Y.H.C Yang ◽  
T.H Kuo ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Anaplastic Astrocytoma ◽  
Conditional Probabilities
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