Mutation of theMYH7 gene in a child with hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome

2007 ◽  
Vol 48 (2) ◽  
pp. 185-188 ◽  
Author(s):  
Waldemar Bobkowski ◽  
Małgorzata Sobieszczańska ◽  
Anna Turska-Kmieć ◽  
Agnieszka Nowak ◽  
Józef Jagielski ◽  
...  
2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Mohammed Abdullahi Talle ◽  
Faruk Buba ◽  
Aimé Bonny ◽  
Musa Mohammed Baba

Syncope is a common manifestation of both hypertrophic cardiomyopathy (HCM) and Wolff-Parkinson-White (WPW) syndrome. The most common arrhythmia in HCM is ventricular tachycardia (VT) and atrial fibrillation (AF). While preexcitation provides the substrate for reentry and supraventricular tachycardia (SVT), AF is more common in patients with preexcitation than the general population. Concurrence of HCM and WPW has been reported in many cases, but whether the prognosis or severity of arrhythmia is different compared to the individual disorders remains unsettled. We report a case of HCM and Wolff-Parkinson-White (WPW) syndrome in a 28-year-old male Nigerian soldier presenting with recurrent syncope and lichen planus.


2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Lutgardo García-Díaz ◽  
Félix Coserria ◽  
Guillermo Antiñolo

A case of prenatally diagnosed fetal hypertrophic cardiomyopathy is reported. The mother was referred to our department at 37 weeks' gestation because of suspected congenital heart disease. Prenatal echocardiography showed biventricular hypertrophy and pericardial effusion, without additional abnormalities. Postnatal echocardiography confirmed prenatal diagnosis. Neonatal EKG showed biventricular hypertrophy and Wolff-Parkinson-White syndrome. Skeletal muscle biopsy was consistent with mitochondrial oxidative phosphorylation defect involving a combined defect of respiratory complexes I and IV. Echocardiographic followup during the first year of life showed progressive regression of hypertrophy and evolution to left ventricular myocardial noncompaction.


2018 ◽  
Vol 29 (2) ◽  
pp. 252-255
Author(s):  
Sunwon Kim ◽  
Woo Hyuk Song ◽  
Sung Soon Kim

AbstractWe present a young soldier presenting with aborted sudden cardiac death, who was found to have concomitant hypertrophic cardiomyopathy and Wolff–Parkinson–White syndrome. Along with pathological haemodynamic features of hypertrophic cardiomyopathy, an easily-inducible re-entrant tachycardia was clearly documented in our patient. Given the fatal potential of supraventricular tachycardia in hypertrophic cardiomyopathy, we postulated that his tachyarrhythmia could potentially trigger the event. Upon his refusal to receive implantable cardioverter/defibrillator therapy, we ablated anatomical arrhythmogenic substrate instead, and he remained uneventfully over 3 years on β-blocker.


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