Drug delivery systems and routes of administration of peptide and protein drugs

1990 ◽  
Vol 15 (2) ◽  
pp. 95-102 ◽  
Author(s):  
L. M. Sanders
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Protein Drugs ◽  
Routes Of Administration

Nanoparticles with surface features of dendritic oligopeptides as potential oral drug delivery systems

2020 ◽  
Vol 8 (13) ◽  
pp. 2636-2649
Author(s):  
Yuli Bai ◽  
Rui Zhou ◽  
Lei Wu ◽  
Yaxian Zheng ◽  
Xi Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Specific Surface ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Delivery Systems ◽  
Oral Drug ◽  
Protein Drugs ◽  
Surface Features ◽  
Oral Drug Delivery Systems

Endowing the NPs with specific surface features of dendritic oligopeptides holds great potential for the oral delivery of peptide/protein drugs.

Characterization of Particulate Drug Delivery Systems for Oral Delivery of Peptide and Protein Drugs

2015 ◽  
Vol 21 (19) ◽  
pp. 2611-2628 ◽  
Author(s):  
Philip Christophersen ◽  
Mathias Fano ◽  
Lasse Saaby ◽  
Mingshi Yang ◽  
Hanne Nielsen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Protein Drugs

scholarly journals OVERVIEW ON METHODS OF SYNTHESIS OF NANOPARTICLES

2021 ◽  
pp. 11-16
Author(s):  
NILESH PATIL ◽  
RAJVEER BHASKAR ◽  
VISHAL VYAVHARE ◽  
RAHUL DHADGE ◽  
VAISHNAVI KHAIRE ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Controlled Drug Release ◽  
Biological Properties ◽  
Delivery Systems ◽  
The Body ◽  
Synthesis Of Nanoparticles ◽  
Routes Of Administration ◽  
Physical Chemical ◽  
Methods Of Synthesis

In recent years, interest in the development of novel drug delivery systems using nanoparticles has gained more attention. The nanoparticles offer several advantages over other conventional drug delivery systems. Nanoparticles have gained importance in technological advancements due to their modifiable physical, chemical and biological properties with improved performance over their bulk foils. Nanoparticles can simply move in the body due to their small size and reach very complex organs through diverse routes. The high stability, controlled drug release makes nanoparticles the most suitable drug delivery system. Along with all these advantages, they offer variety in routes of administration. Both hydrophilic, as well as hydrophobic drugs, can be delivered in the form of nanoparticles. Nanoparticles have been used as a physical approach to modify and advance the pharmacokinetics and pharmacodynamics possessions of various types of drug molecules. Thesol-gel technique is a stress-free and very inexpensive process to formulate metal oxides and permits control over the doping process or adding of transition metals, as related to other research techniques. The study of different methods of synthesis of nanoparticles is essential to obtain desired nanoparticles with specific sizes and shapes. They are suitable candidates for various marketable and local applications, which include imaging, catalysis medical applications and environmental applications. This review mainly focuses on approaches used for the production of nanoparticles and different methods of synthesis of nanoparticles such as physical, chemical and biological method.

scholarly journals Ionic Liquids in Drug Delivery

Encyclopedia ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 324-339
Author(s):  
Sónia N. Pedro ◽  
Carmen S. R. Freire ◽  
Armando J. D. Silvestre ◽  
Mara G. Freire
Keyword(s):  
Drug Delivery ◽  
Ionic Liquids ◽  
Drug Delivery Systems ◽  
Organic Cation ◽  
Delivery Systems ◽  
Ionic Character ◽  
Atmospheric Conditions ◽  
Routes Of Administration ◽  
Pharmaceutical Ingredients ◽  
Novel Drug

Ionic liquids (ILs) are molten salts composed of a large organic cation and an organic/inorganic anion. Due to their ionic character, most ILs present advantageous properties over conventional solvents, such as negligible volatility at atmospheric conditions and high thermal and chemical stabilities. The wide variety of IL anion–cation combinations allows these solvents to be designed to display a strong solvation ability for a myriad of active pharmaceutical ingredients (APIs) and (bio)polymers. Given these properties, ILs have been used as solvents and as formulation components in different areas of drug delivery, as well as novel liquid forms of APIs (API-ILs) applied in different stages of development of novel drug delivery systems. Furthermore, their combination with polymers and biopolymers has enabled the design of drug delivery systems for new therapeutic routes of administration.

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