Investigations on the in vitro metabolism of five synthetic 19-norprogestins using hepatocyte suspensions isolated from five laboratory animal species

1991 ◽  
Vol 16 (2) ◽  
pp. 93-102 ◽  
Author(s):  
L. Qi-Gui ◽  
Z. Ming-Da ◽  
M. Hümpel
Keyword(s):  
Laboratory Animal ◽  
Animal Species ◽  
In Vitro Metabolism

Effect of phenobarbital on the in vitro metabolism of diazepam in several animal species

1970 ◽  
Vol 19 (5) ◽  
pp. 1771-1776 ◽  
Author(s):  
F. Marcucci ◽  
R. Fanelli ◽  
E. Mussini ◽  
S. Garattini
Keyword(s):  
Animal Species ◽  
In Vitro Metabolism

Inhibition of Human and Animal Platelet Adhesiveness to Glass Bead Columns by Adenosine, Dipyridamole, Chlorpromazine and Acetylsalicylic Acid

1976 ◽  
Vol 36 (02) ◽  
pp. 401-410 ◽  
Author(s):  
Buichi Fujttani ◽  
Toshimichi Tsuboi ◽  
Kazuko Takeno ◽  
Kouichi Yoshida ◽  
Masanao Shimizu
Keyword(s):  
Guinea Pig ◽  
Acetylsalicylic Acid ◽  
Guinea Pigs ◽  
Glass Bead ◽  
Animal Species ◽  
Inhibitory Effect ◽  
Rabbit Platelet ◽  
Platelet Adhesiveness

SummaryThe differences among human, rabbit and guinea-pig platelet adhesiveness as for inhibitions by adenosine, dipyridamole, chlorpromazine and acetylsalicylic acid are described, and the influence of measurement conditions on platelet adhesiveness is also reported. Platelet adhesiveness of human and animal species decreased with an increase of heparin concentrations and an increase of flow rate of blood passing through a glass bead column. Human and rabbit platelet adhesiveness was inhibited in vitro by adenosine, dipyridamole and chlorpromazine, but not by acetylsalicylic acid. On the other hand, guinea-pig platelet adhesiveness was inhibited by the four drugs including acetylsalicylic acid. In in vivo study, adenosine, dipyridamole and chlorpromazine inhibited platelet adhesiveness in rabbits and guinea-pigs. Acetylsalicylic acid showed the inhibitory effect in guinea-pigs, but not in rabbits.

scholarly journals In vitro metabolism of retinoic acid in hamster intestine and liver.

1979 ◽  
Vol 254 (14) ◽  
pp. 6296-6302 ◽  
Author(s):  
A B Roberts ◽  
M D Nichols ◽  
D L Newton ◽  
M B Sporn
Keyword(s):  
Retinoic Acid ◽  
In Vitro Metabolism

In vitro metabolism of 3H-androstenedione by the male rat pituitary, hypothalamus, and hippocampus

Steroids ◽  
1975 ◽  
Vol 25 (1) ◽  
pp. 53-62 ◽  
Author(s):  
Ana E. Pérez ◽  
Alfredo Ortíz ◽  
Marisa Cabeza ◽  
Carlos Beyer ◽  
Gregorio Pérez-Palacios
Keyword(s):  
In Vitro Metabolism ◽  
Male Rat ◽  
Rat Pituitary
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