The in vitro metabolism of N,N-dimethylaniline by guinea pig and rabbit tissue preparations

1981 ◽  
Vol 6 (3) ◽  
pp. 195-206 ◽  
Author(s):  
J. W. Gorrod ◽  
N. J. Gooderham
Keyword(s):  
Guinea Pig ◽  
In Vitro Metabolism ◽  
Rabbit Tissue

The effect of age on the in vitro metabolism of androgen by guinea pig testis

Steroids ◽  
1965 ◽  
Vol 6 (6) ◽  
pp. 771-776 ◽  
Author(s):  
Charles A. Snipes ◽  
W.Gary Becker ◽  
C.J. Migeon
Keyword(s):  
Guinea Pig ◽  
In Vitro Metabolism ◽  
Effect Of Age

In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations

2009 ◽  
Vol 27 (1) ◽  
pp. 144-148 ◽  
Author(s):  
Shanthinie Ravindran ◽  
Brian Hopkins ◽  
Sergio Bova ◽  
David Rennison ◽  
Margaret Brimble ◽  
...  
Keyword(s):  
Guinea Pig ◽  
In Vitro Metabolism ◽  
Pig Liver ◽  
Guinea Pig Liver

Inhibition of Human and Animal Platelet Adhesiveness to Glass Bead Columns by Adenosine, Dipyridamole, Chlorpromazine and Acetylsalicylic Acid

1976 ◽  
Vol 36 (02) ◽  
pp. 401-410 ◽  
Author(s):  
Buichi Fujttani ◽  
Toshimichi Tsuboi ◽  
Kazuko Takeno ◽  
Kouichi Yoshida ◽  
Masanao Shimizu
Keyword(s):  
Guinea Pig ◽  
Acetylsalicylic Acid ◽  
Guinea Pigs ◽  
Glass Bead ◽  
Animal Species ◽  
Inhibitory Effect ◽  
Rabbit Platelet ◽  
Platelet Adhesiveness

SummaryThe differences among human, rabbit and guinea-pig platelet adhesiveness as for inhibitions by adenosine, dipyridamole, chlorpromazine and acetylsalicylic acid are described, and the influence of measurement conditions on platelet adhesiveness is also reported. Platelet adhesiveness of human and animal species decreased with an increase of heparin concentrations and an increase of flow rate of blood passing through a glass bead column. Human and rabbit platelet adhesiveness was inhibited in vitro by adenosine, dipyridamole and chlorpromazine, but not by acetylsalicylic acid. On the other hand, guinea-pig platelet adhesiveness was inhibited by the four drugs including acetylsalicylic acid. In in vivo study, adenosine, dipyridamole and chlorpromazine inhibited platelet adhesiveness in rabbits and guinea-pigs. Acetylsalicylic acid showed the inhibitory effect in guinea-pigs, but not in rabbits.

INHIBITION OF LIPOLYTIC ACTIVITY OF SYNTHETIC β1–24 AND β1–39 CORTICOTROPHIN BY ANTI-ACTH ANTISERUM

1966 ◽  
Vol 51 (1) ◽  
pp. 88-94 ◽  
Author(s):  
A. Villanueva ◽  
S. J. H. Ashcroft ◽  
J. P. Felber
Keyword(s):  
Guinea Pig ◽  
Lipolytic Activity ◽  
Peptide Hormones ◽  
Fat Pad ◽  
Double Antibody ◽  
Epididymal Fat ◽  
Antibody Complex ◽  
Radio Immunoassay ◽  
Antigen Antibody

ABSTRACT The synthetic ACTH peptides β1–39 and β1–24 stimulated lipolysis as determined by the rat epididymal fat pad in vitro. The stimulating effect of these peptides was diminished by prior incubation of the peptides with antibodies produced by the guinea-pig against ACTH. The stimulating effect of these hormones was also diminished by the double antibody system used in the radio-immunoassay of ACTH and other peptide hormones, in which incubation with antiserum is followed by precipitation of the antigen-antibody complex by rabbit anti-guinea-pig-γ-globulin.

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