High-density fiber optic array technology and its applications in functional genomic studies

2003 ◽  
Vol 48 (18) ◽  
pp. 1903-1905 ◽  
Author(s):  
Jianbing Fan ◽  
Diping Che ◽  
Chanfeng Zhao ◽  
Lixin Zhou ◽  
Wenyi Feng
2015 ◽  
Vol 6 (5) ◽  
pp. 3139-3147 ◽  
Author(s):  
Sergio Carrasco ◽  
Elena Benito-Peña ◽  
David R. Walt ◽  
María C. Moreno-Bondi

In this article we describe a new class of high-density optical microarrays based on molecularly imprinted microsphere sensors that directly incorporate specific recognition capabilities to detect enrofloxacin (ENRO), an antibiotic widely used for both human and veterinary applications.


2021 ◽  
Vol 22 (11) ◽  
pp. 5723
Author(s):  
Yuan-Yuan Xu ◽  
Sheng-Rui Liu ◽  
Zhi-Meng Gan ◽  
Ren-Fang Zeng ◽  
Jin-Zhi Zhang ◽  
...  

A high-density genetic linkage map is essential for genetic and genomic studies including QTL mapping, genome assembly, and comparative genomic analysis. Here, we constructed a citrus high-density linkage map using SSR and SNP markers, which are evenly distributed across the citrus genome. The integrated linkage map contains 4163 markers with an average distance of 1.12 cM. The female and male linkage maps contain 1478 and 2976 markers with genetic lengths of 1093.90 cM and 1227.03 cM, respectively. Meanwhile, a genetic map comparison demonstrates that the linear order of common markers is highly conserved between the clementine mandarin and Poncirus trifoliata. Based on this high-density integrated citrus genetic map and two years of deciduous phenotypic data, two loci conferring leaf abscission phenotypic variation were detected on scaffold 1 (including 36 genes) and scaffold 8 (including 107 genes) using association analysis. Moreover, the expression patterns of 30 candidate genes were investigated under cold stress conditions because cold temperature is closely linked with the deciduous trait. The developed high-density genetic map will facilitate QTL mapping and genomic studies, and the localization of the leaf abscission deciduous trait will be valuable for understanding the mechanism of this deciduous trait and citrus breeding.


Author(s):  
Mingjie Lyu ◽  
Huafeng Liu ◽  
Joram Kiriga Waititu ◽  
Ying Sun ◽  
Huan Wang ◽  
...  

2010 ◽  
Vol 300 (2-3) ◽  
pp. 88-97 ◽  
Author(s):  
Marie Beaume ◽  
David Hernandez ◽  
Patrice Francois ◽  
Jacques Schrenzel

Author(s):  
Samuel Hone ◽  
Tieyuan Zhu

Abstract Thunderstorms are a common atmospheric phenomenon that cause abundant acoustic disturbances, which can interact with the ground surface, creating a link between atmospheric and solid Earth processes. This article reports seismological observations of four thunderstorms through the spring and summer of 2019, as recorded by the distributed acoustic sensing fiber-optic array (4.9 km) on the Penn State campus in State College, Pennsylvania. With a dense sensor array in the local region, we are able to construct the seismic full waveform response of the thunderstorm events (hereafter referred to as thunderquakes) and track the wave propagation across the array. We use a time-domain grid search to obtain the back azimuth and slowness of the waves, and a modified Geiger’s method to pinpoint source locations of the thunderquakes. Correlated with the time of the recorded signal, this data allows reconstruction of thunderstorm movement as well as offering measurements of the seismic velocity.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Gauri Khandekar ◽  
Seongcheol Kim ◽  
Pudur Jagadeeswaran

Platelets play an important role in mammalian hemostasis. Thrombocytes of early vertebrates are functionally equivalent to mammalian platelets. A substantial amount of research has been done to study platelet function in humans as well as in animal models. However, to date only limited functional genomic studies of platelets have been performed but are low throughput and are not cost-effective. Keeping this in mind we introduced zebrafish, a vertebrate genetic model to study platelet function. We characterized zebrafish thrombocytes and established functional assays study not only their hemostatic function but to also their production. We identified a few genes which play a role in their function and production. Since we introduced the zebrafish model for the study of hemostasis and thrombosis, other groups have adapted this model to study genes that are associated with thrombocyte function and a few novel genes have also been identified. Furthermore, transgenic zebrafish with GFP-tagged thrombocytes have been developed which helped to study the production of thrombocytes and their precursors as well as their functional roles not only in hemostasis but also hematopoiesis. This paper integrates the information available on zebrafish thrombocyte function and its formation.


Author(s):  
Polyana Kelly Martins ◽  
Bárbara Andrade Dias Brito da Cunha ◽  
Adilson Kenji Kobayshi ◽  
Hugo Bruno Correa Molinari

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