Changes of intracellular Na+ concentration in erythrocytes caused by pulsed electrical field

1997 ◽  
Vol 40 (5) ◽  
pp. 488-495 ◽  
Author(s):  
Jinzhu Zhang ◽  
Tong Sun ◽  
Ya Chen ◽  
Shuhua Zhou ◽  
Yunjun Chen ◽  
...  
Keyword(s):  
Electrical Field ◽  
Pulsed Electrical Field

scholarly journals Modular Marx Generator Based on SiC-MOSFET Generating Adjustable Rectangular Pulses

Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3492
Author(s):  
Yahia Achour ◽  
Jacek Starzyński ◽  
Jacek Rąbkowski
Keyword(s):  
Silicon Carbide ◽  
Repetition Rate ◽  
Pulse Width ◽  
Biomedical Applications ◽  
Living Cells ◽  
Marx Generator ◽  
Electrical Field ◽  
Rectangular Shape ◽  
Overall Performance ◽  
Pulsed Electrical Field

The paper introduces a new design of Marx generator based on modular stages using Silicon Carbide MOSFETs (SiC-MOSFET) aimed to be used in biomedical applications. In this process, living cells are treated with intense nanosecond Pulsed Electrical Field (nsPEF). The electric field dose should be controlled by adjusting the pulse parameters such as amplitude, repetition rate and pulse-width. For this purpose, the structure of the proposed generator enables negative pulses with a quasi-rectangular shape, controllable amplitude, pulse-width and repetition-rate. A complete simulation study was conducted in ANSYS-Simplorer to verify the overall performance. A compact, modular prototype of Marx generator was designed with 1.7 kV rated SiC-MOSFETs and, finally, a set of experiments confirmed all expected features.

Primer on Pulsed Electrical Field Ablation: Understanding the Benefits and Limitations

2021 ◽  
Author(s):  
Atul Verma ◽  
Samuel J. Asivatham ◽  
Thomas Deneke ◽  
Quim Castellvi ◽  
Robert E Neal
Keyword(s):  
Cardiac Arrhythmias ◽  
Target Tissue ◽  
Electrical Characteristics ◽  
Efficacy And Safety ◽  
Promising Technique ◽  
Electrical Field ◽  
Important Benefit ◽  
Pulsed Electrical Field ◽  
Key Aspects ◽  
Stromal Proteins

Pulsed electrical field (PEF) energy is a promising technique for catheter ablation of cardiac arrhythmias. In this article, the key aspects that need to be considered for safe and effective PEF delivery are reviewed, and their impact on clinical feasibility is discussed. The most important benefit of PEF appears to be the ability to kill cells through mechanisms that do not alter stromal proteins, sparing sensitive structures to improve safety, without sacrificing cardiomyocyte ablation efficacy. Many parameters affect PEF treatment outcomes, including pulse intensity, waveform shape, and number of pulses, as well as electrode configuration and geometry. These physical and electrical characteristics must be titrated carefully to balance target tissue effects with collateral implications (muscle contraction, temperature rise, risk of electrical arcing events). It is important to note that any combination of parameters affecting PEF needs to be tested for clinical efficacy and safety. Applying PEF clinically requires knowledge of the fundamentals of this technology to exploit its opportunities and generate viable, durable health improvements for patients.

scholarly journals Effect of Pulsed Electrical Field on Deposition of YSZ Thin Films in an Aqueous Solution

2010 ◽  
Vol 51 (2) ◽  
pp. 297-300 ◽  
Author(s):  
Atsushi Saiki ◽  
Takashi Hashizume ◽  
Kiyoshi Terayama
Keyword(s):  
Thin Films ◽  
Aqueous Solution ◽  
Electrical Field ◽  
Pulsed Electrical Field

Pasteurization of Milk Using Pulsed Electrical Field and Antimicrobials

2002 ◽  
Vol 67 (6) ◽  
pp. 2304-2308 ◽  
Author(s):  
K. Smith ◽  
G.S. Mittal ◽  
M.W. Griffiths
Keyword(s):  
Electrical Field ◽  
Pulsed Electrical Field

scholarly journals Fabrication Of YSZ Thin Film By Electrochemical Deposition Method And The Effect Of The Pulsed Electrical Fields For Morphology Control

2015 ◽  
Vol 60 (2) ◽  
pp. 945-948
Author(s):  
T. Fujita ◽  
A. Saiki ◽  
T. Hashizume
Keyword(s):  
Thin Film ◽  
Precursor Solution ◽  
Morphology Control ◽  
Film Deposition ◽  
Electrical Field ◽  
Electrical Fields ◽  
Electrochemical Deposition Method ◽  
Deposition Direction ◽  
Pulsed Electrical Field ◽  
Pulsed Voltage

Abstract In this study, surface morphology control ions in a precursor solution and patterning the YSZ film has been carried out during deposition of thin film from a precursor solution by applying the electrical field for deposition and the pulsed electrical field. The precursor solution was mixed them of ZrO(NO3)4, Y(NO3)3-6H2O into deionized water, and then was controlled nearly pH3 by adding NH3(aq). The thin film was deposited on the glass substrate of the minus electrode side by applying the electrical field of 3.0 V for 20 min. In addition, another pulsed voltage was applied to the electrical field along the perdicular direction to the film deposition direction. After annealing samples at 773 K for 6 h in air, the film was crystallized and obtained YSZ film. In the limited condition, the linear patterns of YSZ films due to the frequency of the applied electrical field were observed. It is expected that ions in a precursor solution are controlled by applying the pulsed voltage and the YSZ film is patterned on the substrate.

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