Development of new immunoradiometric assay for CA 125 antigen using two monoclonal antibodies produced by immunizing lung cancer cells

1988 ◽  
Vol 2 (2) ◽  
pp. 73-79 ◽  
Author(s):  
Mihoko Kunimatsu ◽  
Keigo Endo ◽  
Tetsuo Nakashima ◽  
Toshikazu Awaji ◽  
Tsuneo Saga ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Monoclonal Antibodies ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Ca 125 ◽  
Immunoradiometric Assay ◽  
Ca 125 Antigen

Immunocytochemical detection of lung cancer cells with monoclonal antibodies to 14-3-3 proteins

1995 ◽  
Vol 6 (4) ◽  
pp. 137-144 ◽  
Author(s):  
Yuko Setoguchi ◽  
Masatoshi Kato ◽  
Masahiro Shoji ◽  
Tsutomu Honjoh ◽  
Masanori Kamei ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Monoclonal Antibodies ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
Immunocytochemical Detection

scholarly journals Mechanisms for the Apoptosis of Small Cell Lung Cancer Cells Induced by Anti-GD2 Monoclonal Antibodies

2005 ◽  
Vol 280 (33) ◽  
pp. 29828-29836 ◽  
Author(s):  
Wei Aixinjueluo ◽  
Keiko Furukawa ◽  
Qing Zhang ◽  
Kazunori Hamamura ◽  
Noriyo Tokuda ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Monoclonal Antibodies ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Lung Cancer Cells ◽  
Small Cell Lung

Methods for production of monoclonal antibodies with specificity for human lung cancer cells

In Vitro ◽  
1981 ◽  
Vol 17 (12) ◽  
pp. 1058-1070 ◽  
Author(s):  
John D. Minna ◽  
Frank Cuttitta ◽  
Steven Rosen ◽  
Paul A. Bunn ◽  
Desmond N. Carney ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Monoclonal Antibodies ◽  
Cancer Cells ◽  
Human Lung ◽  
Lung Cancer Cells ◽  
Human Lung Cancer ◽  
Human Lung Cancer Cells

Inhibitory effects of Actinidia Chinensis planch root extracts (acRoots) on human lung cancer cells through retinoic acid receptor beta

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Lingyan Wang ◽  
Jiayun Hou ◽  
Minghuan Zheng ◽  
Lin Shi
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Human Lung ◽  
Retinoic Acid Receptor ◽  
Lung Cancer Cells ◽  
Human Lung Cancer ◽  
Inhibitory Effects ◽  
The Core ◽  
Human Lung Cancer Cells ◽  
Receptor Beta

Actinidia Chinensis Planch roots (acRoots) are used to treat many cancers, although the anti-tumor mechanism by which acRoots inhibit cancer cell growth remains unclear. The present study aims at investigating inhibitory effects of acRoots on human lung cancer cells and potential mechanisms. Our data demonstrate that the inhibitory effects of acRoots on lung cancer cells depend on genetic backgrounds and phenotypes of cells. We furthermore found the expression of metabolism-associated gene profiles varied between acRoots-hypersensitive (H460) or hyposensitive lung cancer cells (H1299) after screening lung cancer cells with different genetic backgrounds. We selected retinoic acid receptor beta (RARB) as the core target within metabolism-associated core gene networks and evaluated RARB changes and roles in cells treated with acRoots at different concentrations and timeframes. Hypersensitive cancer cells with the deletion of RARB expression did not response to the treatment with acRoots, while RARB deletion did not change effects of acRoots on hyposensitive cells. Thus, it seems that RARB as the core target within metabolism-associated networks plays important roles in the regulation of lung cancer cell sensitivity to acRoots.

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