scholarly journals Cosmonauts and lead: Resorption and increased blood lead levels during long term space flight

2006 ◽  
Vol 2 (4) ◽  
pp. 172-173 ◽  
Author(s):  
Vladislav S. Kondrashov
Keyword(s):  
Space Flight ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Term Space Flight ◽  
Lead Levels

Long-Term Trends in Blood Lead Levels Among Children in Chicago: Relationship to Air Lead Levels

PEDIATRICS ◽  
1994 ◽  
Vol 93 (2) ◽  
pp. 195-200
Author(s):  
Edward B. Hayes ◽  
Hyman G. Orbach ◽  
Alina M. Fernandez ◽  
Sheila Lyne ◽  
Thomas D. Matte ◽  
...  
Keyword(s):  
High Risk ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Lead Levels ◽  
Level Of Concern ◽  
The Impact

Objectives. To evaluate trends in blood lead levels among children in Chicago from 1968 through 1988, and to determine the impact of the changes in the Centers for Disease Control and Prevention (CDC) blood lead level of concern. Methods. We reviewed a systematic sample of blood lead screening records of the Chicago Department of Health Laboratory for high-risk children aged 6 months to 5 years. Median blood lead levels for each quarter of the years 1974 through 1988 were determined and regressed against mean air lead levels recorded at air-monitoring stations in Chicago during the same period. Results. Median blood lead levels declined from 30 µg/dL in 1968 to 12 µg/dL in 1988, and were strongly associated with declining average air lead levels (r = .8, P < .001) from 1974 through 1988. A regression model using log-transformed data predicted a decline of 0.56 µg/dL in the median blood lead level with each 0.1 µg/m3 decline in the mean air lead level when the air lead level was near 1.0 µg/m3; the predicted slope was steeper at lower air lead levels. Despite the nearly 20-fold reduction in air lead levels, the median blood lead level of 12 µg/dL in 1988 indicates substantial continuing lead exposure. The CDC blood lead level of concern was lowered twice from 1968 to 1988, but due to the decline in blood lead levels, fewer than 30% of the children were above the level of concern throughout most of the study. Conclusion. Although substantial lead exposure persists in Chicago, reductions in airborne lead emissions seem to have contributed to a long-term decline in the median blood lead level of high-risk Chicago children.

Letter To The Editor

PEDIATRICS ◽  
1996 ◽  
Vol 98 (1) ◽  
pp. 162-163 ◽  
Author(s):  
George G. Rhoads ◽  
Walter J. Rogan
Keyword(s):  
Treatment Guidelines ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Environmental Health Sciences ◽  
Research Protocols ◽  
Lead Levels

We read with interest the carefully updated "Treatment Guidelines for Lead Exposure in Children" issued by the AAP Committee on Drugs.1 The Committee identifies the major remaining question regarding the role of succimer as the indications for its use in patients with blood lead levels in the range of 25 µg/dL to 44 µg/dL. The Committee also mentions that the National Institute of Environmental Health Sciences is supporting a study on the long-term outcome after treatment with succimer, and strongly endorses participation in current research protocols.

In Vivo X-Ray Fluorescence of Bone Lead in the Study of Human Lead Metabolism: Serum Lead, Whole Blood Lead, Bone Lead, and Cumulative Exposure

1994 ◽  
Vol 38 ◽  
pp. 601-606 ◽  
Author(s):  
K.M. Cake ◽  
D.R. Chettle ◽  
C.E. Webber ◽  
C.L. Gordon ◽  
R.J. Bowins ◽  
...  
Keyword(s):  
Body Burden ◽  
Blood Lead ◽  
Cumulative Exposure ◽  
Blood Lead Levels ◽  
X Ray ◽  
Lead Metabolism ◽  
Bone Lead ◽  
Lead Levels

Traditionally, clinical studies of lead's effect on health have relied on blood lead levels to indicate lead exposure. However, this is unsatisfactory because blood lead levels have a half-life of approximately 5 weeks (Rabinowitz et al., 1976), and thus reflect recent exposure. Over 90% of the lead body burden is in bone, and it is thought to have a long residence time, thus implying that measurements of bone lead reflect cumulative exposure (Barry, 1975). So, measurements of bone lead are useful m understanding the long-term health effects of lead.

Blood Lead Levels, Malnutrition, Inflammation, and Mortality in Patients With Diabetes Treated by Long-Term Hemodialysis

2008 ◽  
Vol 51 (1) ◽  
pp. 107-115 ◽  
Author(s):  
Ja-Liang Lin ◽  
Dan-Tzu Lin-Tan ◽  
Tzung-Hai Yen ◽  
Ching-Wei Hsu ◽  
Chang-Chyi Jenq ◽  
...  
Keyword(s):  
Blood Lead ◽  
Blood Lead Levels ◽  
Patients With Diabetes ◽  
Lead Levels

Blood lead levels in patients with lead shot retained in the appendix

1988 ◽  
Vol 29 (6) ◽  
pp. 745-746 ◽  
Author(s):  
H. H. T. Madsen ◽  
T. Skjødt ◽  
P. J. Jørgensen ◽  
P. Grandjean
Keyword(s):  
Blood Lead ◽  
Lead Shot ◽  
Blood Lead Levels ◽  
Lead Levels
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