Differential responsiveness against mechanical stress between osteoblastic cells and periodontal ligament cells

1998 ◽  
Vol 86 (1) ◽  
pp. 64-71
Author(s):  
Shigekazu Yasui ◽  
Takashi Maeda ◽  
Takashi Kameda
Keyword(s):  
Mechanical Stress ◽  
Periodontal Ligament ◽  
Osteoblastic Cells ◽  
Periodontal Ligament Cells ◽  
Differential Responsiveness

Unique genes induced by mechanical stress in periodontal ligament cells

2003 ◽  
Vol 38 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Fumio Myokai ◽  
Masataka Oyama ◽  
Fusanori Nishimura ◽  
Taisuke Ohira ◽  
Tadashi Yamamoto ◽  
...  
Keyword(s):  
Mechanical Stress ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cells ◽  
Unique Genes

Initial Responses of Periodontal Ligament Cells Induced by Mechanical Stress

2001 ◽  
Vol 2001.13 (0) ◽  
pp. 192-193
Author(s):  
Mirei CHIBA ◽  
Nozomi YAMAGUCHI ◽  
Hiroyuki KANZAKI ◽  
Mamoru KUBOTA ◽  
Hideo MITANI
Keyword(s):  
Mechanical Stress ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cells

scholarly journals Cadherin-11 modulates cell morphology and collagen synthesis in periodontal ligament cells under mechanical stress

2016 ◽  
Vol 87 (2) ◽  
pp. 193-199 ◽  
Author(s):  
Lishu Feng ◽  
Yimei Zhang ◽  
Xiaoxing Kou ◽  
Ruili Yang ◽  
Dawei Liu ◽  
...  
Keyword(s):  
Mechanical Stress ◽  
Mechanical Stimulation ◽  
Cell Morphology ◽  
Periodontal Ligament ◽  
Collagen Synthesis ◽  
Treatment Time ◽  
Blue Staining ◽  
Periodontal Ligament Cells ◽  
Type I ◽  
Dependent Manner

ABSTRACT Objective: To examine the role of cadherin-11, an integral membrane adhesion molecule, in periodontal ligament cells (PDLCs) under mechanical stimulation. Materials and Methods: Human PDLCs were cultured and subjected to mechanical stress. Cadherin-11 expression and cell morphology of PDLCs were investigated via immunofluorescence staining. The mRNA and protein expressions of cadherin-11 and type I collagen (Col-I) of PDLCs were evaluated by quantitative real-time polymerase chain reaction and Western blot, respectively. Small interfering RNA was used to knock down cadherin-11 expression in PDLCs. The collagen matrix of PDLCs was examined using toluidine blue staining. Results: Cadherin-11 was expressed in PDLCs. Mechanical stress suppressed cadherin-11 expression in PDLCs with prolonged force treatment time and increased force intensity, accompanied by suppressed β-catenin expression. Simultaneously, mechanical stress altered cell morphology and repressed Col-I expression in a time- and dose-dependent manner in PDLCs. Moreover, knockdown of cadherin-11 with suppressed β-catenin expression resulted in altered PDLC morphology and repressed collagen expression, which were consistent with the changes observed under mechanical stress. Conclusions: Results of this study suggest that cadherin-11 is expressed in PDLCs and modulates PDLC morphology and collagen synthesis in response to mechanical stress, which may play an important role in the homeostasis and remodeling of the PDL under mechanical stimulation.

scholarly journals Mechanical stress alters protein O‐GlcNAc in human periodontal ligament cells

2019 ◽  
Vol 23 (9) ◽  
pp. 6251-6259 ◽  
Author(s):  
Dorottya Frank ◽  
Annamária Cser ◽  
Béla Kolarovszki ◽  
Nelli Farkas ◽  
Attila Miseta ◽  
...  
Keyword(s):  
Mechanical Stress ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cells ◽  
Human Periodontal Ligament Cells
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