Twenty-Four hour ambulatory blood pressure profile of a new slow-release formulation of diltiazem in mild to moderate hypertension

1991 ◽  
Vol 5 (4) ◽  
pp. 701-707 ◽  
Author(s):  
Alain G. Dupont ◽  
Jean M. Coupez ◽  
Patrick Jensen ◽  
Renée Coupez-Lopinot ◽  
Danny F. Schoors ◽  
...  
1980 ◽  
Vol 8 (1) ◽  
pp. 44-49 ◽  
Author(s):  
Jaakko Tuomilehto ◽  
Aulikki Nissinen

The antihypertensive effect and the tolerability of metoprolol Durules® have been studied in fifty-five patients with mild to moderate hypertension. The patients' diastolic blood pressure was ≥95 mm Hg in order to qualify for entry. Thirty-seven out of fifty-three patients completing the study (70%) were treated with metoprolol Durules® monotherapy throughout the study. The mean blood pressure was reduced from 153/101 to 138/92 mm Hg after metoprolol Durules® compared to placebo (p < 0.001). Twenty-seven patients received one Durules® daily and ten patients received two Durules® daily as the final dose. Of the sixteen patients not responding on metoprolol Durules®, six patients achieved satisfactory control, i.e. a diastolic blood pressure below 95 mm Hg, when given 200 mg metoprolol + 25 mg hydrochlorothiazide (HCT). The results indicate that most patients with, mild or moderate hypertension can be controlled with metoprolol Durules® monotherapy given once daily. The addition of HCT gives a significant benefit in moderate hypertension, where metoprolol monotherapy is not sufficient.


1999 ◽  
Vol 4 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Anna M. Grandi ◽  
Roberta Broggi ◽  
Paolo Zanzi ◽  
Giovanni Gaudio ◽  
Rosa Santillo ◽  
...  

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e256
Author(s):  
K. Konstantinou ◽  
K. Tsioufis ◽  
M. Mantzouranis ◽  
A. Koumelli ◽  
C. Fragoulis ◽  
...  

2020 ◽  
Vol 43 (9) ◽  
pp. 903-913 ◽  
Author(s):  
Maria Eleni Alexandrou ◽  
Charalampos Loutradis ◽  
Maria Schoina ◽  
Georgios Tzanis ◽  
Chrysostomos Dimitriadis ◽  
...  

Circulation ◽  
1982 ◽  
Vol 65 (1) ◽  
pp. 22-27 ◽  
Author(s):  
B A Gould ◽  
S Mann ◽  
H Kieso ◽  
V B Subramanian ◽  
E B Raftery

Hypertension ◽  
2014 ◽  
Vol 63 (5) ◽  
pp. 913-914 ◽  
Author(s):  
Gianpaolo Reboldi ◽  
Fabio Angeli ◽  
Paolo Verdecchia

2010 ◽  
Vol 34 (2) ◽  
pp. 253-256 ◽  
Author(s):  
Gregory Vyssoulis ◽  
Eva Karpanou ◽  
Stella-Maria Kyvelou ◽  
Vanessa Tzamou ◽  
Andreas Triantafyllou ◽  
...  

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