Dural sinus thrombosis in a late preeclamptic woman

2004 ◽  
Vol 51 (10) ◽  
pp. 1050-1051 ◽  
Author(s):  
Antoni Arxer ◽  
Berta Pardina ◽  
Itziar Blas ◽  
Lluís Ramió ◽  
Antonio Villalonga
Keyword(s):  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis ◽  
Preeclamptic Woman

Extensive Experience with Dural Sinus Thrombosis

Neurosurgery ◽  
2003 ◽  
Vol 52 (3) ◽  
pp. 534-544 ◽  
Author(s):  
Scott W. Soleau ◽  
Richard Schmidt ◽  
Steve Stevens ◽  
Anne Osborn ◽  
Joel D. MacDonald
Keyword(s):  
Clinical Improvement ◽  
Sinus Thrombosis ◽  
Treatment Strategies ◽  
Retrospective Chart Review ◽  
Dural Sinus ◽  
Hemorrhagic Complication ◽  
Dural Sinus Thrombosis ◽  
Extensive Experience ◽  
Medical Observation ◽  
Hemorrhagic Complications

Abstract OBJECTIVE Dural sinus thrombosis (DST) is an uncommon cause of stroke. The safest and most effective therapy for DST has not been conclusively identified. METHODS A retrospective chart review of data for 31 patients who were treated for DST at our institution between 1992 and 2001 was performed. Four treatment strategies were identified, i.e., 1) medical observation only, 2) systemic anticoagulation (AC) therapy with heparin, 3) endovascular chemical thrombolysis with urokinase or tissue plasminogen activator and concurrent systemic AC therapy, and 4) mechanical endovascular clot thrombolysis with concurrent systemic AC therapy. Complications and clinical outcomes were assessed for each group. RESULTS Patients treated solely with medical observation fared the worst; four of five patients experienced intracranial hemorrhagic complications, and only two of five exhibited clinical improvement. Patients who received systemic AC therapy experienced no hemorrhagic complications, even when pretreatment hemorrhage was present; 75% (six of eight patients) exhibited improvement with AC therapy alone. Chemical thrombolysis was very effective in restoring sinus patency (90% of patients); however, 30% of patients (3 of 10 patients) experienced hemorrhagic complications. Sixty percent of patients (6 of 10 patients) who underwent chemical thrombolysis exhibited clinical improvement. Patients who underwent mechanical thrombectomies demonstrated a low hemorrhagic complication rate, and most (88%) made good recoveries. CONCLUSION Therapy directed at the underlying clot in DST must begin without delay. Our results suggest that supportive medical management of DST, without therapy directed at the clot or clotting process, is not effective. Systemic AC therapy, even in the presence of intracerebral hemorrhage, seems to be safe. Heparin can be safely titrated to yield partial thromboplastin times of 60 to 70 seconds. Chemical clot thrombolysis is efficacious in opening occluded sinuses but may cause intracranial hemorrhage. We currently recommend either systemic AC therapy or systemic AC therapy in conjunction with mechanical clot thrombectomy as a safe effective treatment for DST.

scholarly journals Risk factors for remote seizure development in patients with cerebral vein and dural sinus thrombosis

Seizure ◽  
2014 ◽  
Vol 23 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Vahid Davoudi ◽  
Kiandokht keyhanian ◽  
Mohammad Saadatnia
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Cerebral Vein ◽  
Dural Sinus Thrombosis

MR imaging of dural sinus thrombosis: A case report

1993 ◽  
Vol 29 (1) ◽  
pp. 51
Author(s):  
Si Kyung Lee ◽  
Chun Hwan Han ◽  
Moon Ok Lee ◽  
Kyung Joo Park ◽  
Joo Hyuk Lee
Keyword(s):  
Case Report ◽  
Mr Imaging ◽  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis

Dural sinus thrombosis in early life

1937 ◽  
Vol 11 (6) ◽  
pp. 755-771 ◽  
Author(s):  
Orville T. Bailey ◽  
George M. Hass
Keyword(s):  
Early Life ◽  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis

Prenatal diagnosis of a spontaneous dural sinus thrombosis

2009 ◽  
Vol 29 (8) ◽  
pp. 808-813 ◽  
Author(s):  
G. Legendre ◽  
O. Picone ◽  
J. M. Levaillant ◽  
J. Delavaucoupet ◽  
A. Ozanne ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis

Fatal Dural Sinus Thrombosis Associated With Heterozygous Factor V Leiden and a Short Activated Partial Thromboplastin Time

2003 ◽  
Vol 127 (10) ◽  
pp. 1359-1361 ◽  
Author(s):  
Christina L. Stephan ◽  
Karen SantaCruz ◽  
Corrie May ◽  
Steve B. Wilkinson ◽  
Mark T. Cunningham
Keyword(s):  
Partial Thromboplastin Time ◽  
Primary Motor Cortex ◽  
Sinus Thrombosis ◽  
Factor V Leiden ◽  
Activated Partial Thromboplastin Time ◽  
Dural Sinus ◽  
Factor V ◽  
Dural Sinus Thrombosis ◽  
Factor V Leiden Mutation ◽  
Parietal Lobes

Abstract Inherited thrombophilia is a risk factor for dural sinus thrombosis (DST). To our knowledge, this is the first description with autopsy findings of a patient with DST associated with heterozygous factor V Leiden and a short activated partial thromboplastin time (aPTT). A 51-year-old woman presented with a 3-day history of headache, nausea, right-sided weakness, and focal motor seizure; she died 3 days after admission. At autopsy, a gross examination showed hemorrhage of bilateral parietal lobes and left primary motor cortex, uncal and tonsillar herniation, and pulmonary embolus of the right upper lobe. A microscopic examination of the brain showed an organizing thrombus in the superior sagittal sinus, diffuse cerebral edema, and extensive venous congestion. Laboratory studies showed heterozygous factor V Leiden by polymerase chain reaction and a very short aPTT of 17 seconds (reference range, 22–30 seconds). The combination of a heterozygous factor V Leiden mutation and a short aPTT may have contributed to the fatal DST in this patient.

Dural Sinus Thrombosis

2015 ◽  
pp. 1-2
Author(s):  
Neil M. D’Souza ◽  
Sumayya J. Almarzouqi ◽  
Michael L. Morgan ◽  
Andrew G. Lee
Keyword(s):  
Sinus Thrombosis ◽  
Dural Sinus ◽  
Dural Sinus Thrombosis
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