Ginkgo biloba extract (GBE) and the vestibular system : A craniocorpographic and electronystagmographic assessment

1989 ◽  
Vol 41 (2) ◽  
pp. 59-60
Author(s):  
N. P. Patil
Keyword(s):  
Vestibular System ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
System A

scholarly journals Persistent postural-perceptual dizziness: current approaches to diagnosis and treatment

2019 ◽  
Vol 11 (4) ◽  
pp. 136-140
Author(s):  
L. M. Antonenko ◽  
E. N. Zastenskaya
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Vestibular System ◽  
Ginkgo Biloba ◽  
Behavioral Therapy ◽  
Regulatory System ◽  
Ginkgo Biloba Extract ◽  
Cognitive Behavioral ◽  
Vestibular Compensation ◽  
Diagnosis And Treatment ◽  
New Treatments

The cause of persistent postural-perceptual dizziness (PPPD) is considered to be chronic dysfunction of the regulatory system for maintaining equilibrium in general and that of the vestibular system in particular, which causes a persistent sensation of dizziness and/or unsteadiness. The pathogenetic mechanisms of PPPD are associated with impaired adaptation to an acute vertigo or unsteadiness episode due to various causes (vestibular, lipothymic, or emotional). Patients severely experience PPPD, which often leads to avoidant behavior and even disability. The timely diagnosis of this disorder and the use of right treatment, including vestibular rehabilitation, antidepressants, and cognitive behavioral therapy, are of great importance. Currently developed new treatments for PPPD are highly therapeutically effective. Among the medicines, Ginkgo biloba extract has been shown to be effective in improving vestibular compensation.

Effects of Ginkgo biloba extract (EGb 761) on the guinea pig vestibular system

1992 ◽  
Vol 42 (4) ◽  
pp. 595-604 ◽  
Author(s):  
Takao Yabe ◽  
Mireille Chat ◽  
Eric Malherbe ◽  
Pierre-Paul Vidal
Keyword(s):  
Guinea Pig ◽  
Vestibular System ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Egb 761

Quality Control Optimization Solutions for Determination of Rutin in Supplements Containing Ginkgo Biloba Extract

2016 ◽  
Vol 12 (4) ◽  
pp. 386-390 ◽  
Author(s):  
Ivanka P. Pencheva ◽  
Vania N. Maslarska ◽  
Assena C. Stoimenova ◽  
Manoela M. Manova ◽  
Lily A. Andonova ◽  
...  
Keyword(s):  
Quality Control ◽  
Ginkgo Biloba ◽  
Ginkgo Biloba Extract ◽  
Control Optimization

Quantitative GC-FID and UHPLC-DAD Evaluation of Bioactive Compounds Extracted from Ginkgo biloba

2020 ◽  
Vol 16 (7) ◽  
pp. 893-904
Author(s):  
Alessandra von Ahn ◽  
João Henrique Z. dos Santos
Keyword(s):  
Ginkgo Biloba ◽  
Extraction Efficiency ◽  
Extraction Methods ◽  
Ginkgo Biloba Extract ◽  
Previous Method ◽  
Array Detector ◽  
Ginkgolide B ◽  
Detection Techniques ◽  
Ginkgolide A ◽  
Terpene Trilactones

Background: The official compendium of the quantification of ginkgo flavonoids from Ginkgo biloba extract has been proposed using HPLC. The drawbacks of this technique appear to be due to the restricted efficiency in terms of the recovery results and suitability of the system for the quantification of these compounds. This study investigated the potential advantages and limitations of the development of efficient extraction methods for the recovery of flavonol glycosides (quercetin, kaempferol and isorhamnetin) and terpene trilactones (bilobalide, ginkgolide A, ginkgolide B and ginkgolide C) using extraction, quantification and detection techniques, namely, GC-FID and UHPLC-DAD, which are alternatives to those techniques available in the literature. Methods: Two different extraction methodologies have been developed for the determination of flavonoids (quercetin, kaempferol and isorhamnetin) and terpene trilactones (bilobalide, ginkgolide A, ginkgolide B and ginkgolide C) using ultra-high-pressure liquid chromatography coupled to a diode array detector and gas chromatography coupled to a flame ionization detector. Results: In this study, the Ginkgo biloba extract mass, hydrolysis preparation method (with or without reflux), and volume of the extraction solution seemed to affect the ginkgo flavonoid recovery. The UHPLC-based method exhibited higher extraction efficiency for ginkgo flavonoid quantification compared to the pharmacopoeial method. The developed method exhibited higher extraction efficiency for terpene quantification compared to the previous method that used extractive solution without pH adjustment, with less time of extraction and less amount of the sample and organic solvent aliquots. Conclusion: The UHPLC and GC analysis methods established in this study are both effective and efficient. These methods may improve the quality control procedures for ginkgo extract and commercial products available in today´s natural health product market. The results indicate that redeveloped extraction methods can be a viable alternative to traditional extraction methods.

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