Quality of ulcer healing—A new concept to rank healed peptic ulcers

1993 ◽  
Vol 28 (S5) ◽  
pp. 158-162 ◽  
Author(s):  
Tetsuo Arakawa ◽  
Kenzo Kobayashi
1995 ◽  
Vol 41 (4) ◽  
pp. 365
Author(s):  
K. Higuchi ◽  
T. Uchida ◽  
H. Nebiki ◽  
H. Itoh ◽  
T. Fukuda ◽  
...  

1995 ◽  
Vol 20 ◽  
pp. S40-S43 ◽  
Author(s):  
Yoshihisa Tsukamoto ◽  
Hidemi Goto ◽  
Satoshi Hase ◽  
Yasumasa Niwa ◽  
Tomiyasu Arisawa ◽  
...  

1995 ◽  
Vol 20 ◽  
pp. S62-S66 ◽  
Author(s):  
Go Ito ◽  
Masanori Nakagawara ◽  
Fumitoshi Watanabe ◽  
Sigeko Ooi ◽  
Mitsumasa Nawano ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Lin Wang ◽  
Wei-Zhi Liu ◽  
Ling-Yan Pei ◽  
Yu-Shi Ke ◽  
Jian Cui ◽  
...  

Garidisan, commonly used in Mongolia to treat ulcerative colitis (UC), contains wild poppy andArtemisia frigidaWilld. Clinical evidence shows that Garidisan can effectively treat UC and that recurrence is low. Thus, we evaluated the effects of Garidisan on ulcer healing quality and the regulation of immune balance in rats with experimental UC. UC was induced by immunization with TNBS and Garidisan significantly reduced DAI, CMDI, and HS. H&E staining, SEM, and VG staining showed that Garidisan repaired damaged intestinal mucosa and significantly reduced expression of ICAM-1 and CD105 in regenerated tissues of UC rats. Collagen fibers were significantly fewer as well after treatment. Garidisan elevated EGF, VEGF, bFGF, VEGFR2, and FGFR1 of UC rats, reduced CD3+CD4+/CD3+CD8+T cell ratios, and increased CD4+Th1/CD4+Th2 cell ratios and IFN-r/IL-4 ratios in peripheral blood of UC rats. In conclusion, Garidisan promoted tissue maturation of regenerated tissues by regulating the immune balance and improved functional maturity of regenerated tissues by reducing collagen formation, promoting maturation of new blood vessels, and increasing expression of growth factors and their receptors.


2003 ◽  
Vol 124 (4) ◽  
pp. A447
Author(s):  
Tae Young Oh ◽  
Ju Mi Kim ◽  
Seul Min Choi ◽  
Jae Hoon Choi ◽  
Byoung Ok Ahn ◽  
...  

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