Construction of eukaryotic expression vector with granulocyte-macrophage colony-stimulating factor gene

2000 ◽  
Vol 12 (2) ◽  
pp. 125-127 ◽  
Author(s):  
Qiu-hong Zheng ◽  
Tian-rong Zheng ◽  
Yun-qing Xie ◽  
Lin Lu ◽  
Hui Chen
2008 ◽  
Vol 53 (1) ◽  
pp. 306-308 ◽  
Author(s):  
Lisa K. Woolhiser ◽  
Donald R. Hoff ◽  
Karen S. Marietta ◽  
Ian M. Orme ◽  
Anne J. Lenaerts

ABSTRACT This study describes an in vivo model for evaluating the sterilizing activity of compounds against persisting Mycobacterium tuberculosis. The initial treatment with isoniazid and rifampin in granulocyte-macrophage colony-stimulating factor gene-disrupted mice reduced the number of bacteria more than 99% within 3 weeks. A subsequent treatment with individual drugs was performed to assess their activity on the 1% of remaining bacilli and disease relapse.


1994 ◽  
Vol 15 (5) ◽  
pp. 1017-1029 ◽  
Author(s):  
Fredika M. Robertson ◽  
Gautam N. Bijur ◽  
Andrew S. Oberyszyn ◽  
Arthur E. Pellegrini ◽  
Laszlo G. Boros ◽  
...  

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