Ricin A immunotoxins of IgG and Fab of anti-CALLA monoclonal antibody: Effect of water soluble long-chain SPDP on conjugate yield, immunoselectivity and cytotoxicity

1994 ◽  
Vol 17 (6) ◽  
pp. 452-457 ◽  
Author(s):  
Byung Ho Woo ◽  
Jung Tae Lee ◽  
Kang Choon Lee
Keyword(s):  
Monoclonal Antibody ◽  
Water Soluble ◽  
Effect Of Water ◽  
Ricin A ◽  
Long Chain

Stability and cytotoxicity of Fab-ricin A immunotoxins prepared with water soluble long chain heterobifunctional crosslinking agents

1999 ◽  
Vol 22 (5) ◽  
pp. 459-463 ◽  
Author(s):  
Byung Ho Woo ◽  
Jung Tae Lee ◽  
Myung Ok Park ◽  
Kang Ro Lee ◽  
Jeung Whan Han ◽  
...  
Keyword(s):  
Water Soluble ◽  
Crosslinking Agents ◽  
Ricin A ◽  
Long Chain

scholarly journals Optimizing Chitin Depolymerization by Lysozyme to Long-Chain Oligosaccharides

Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 320
Author(s):  
Arnaud Masselin ◽  
Antoine Rousseau ◽  
Stéphanie Pradeau ◽  
Laure Fort ◽  
Rodolphe Gueret ◽  
...  
Keyword(s):  
Time Course ◽  
Water Soluble ◽  
Organic Fertilizers ◽  
Symbiotic Associations ◽  
Egg White Lysozyme ◽  
Hen Egg White ◽  
Ecological Transition ◽  
Optimized Conditions ◽  
Hydrolysis Of ◽  
Long Chain

Chitin oligosaccharides (COs) hold high promise as organic fertilizers in the ongoing agro-ecological transition. Short- and long-chain COs can contribute to the establishment of symbiotic associations between plants and microorganisms, facilitating the uptake of soil nutrients by host plants. Long-chain COs trigger plant innate immunity. A fine investigation of these different signaling pathways requires improving the access to high-purity COs. Here, we used the response surface methodology to optimize the production of COs by enzymatic hydrolysis of water-soluble chitin (WSC) with hen egg-white lysozyme. The influence of WSC concentration, its acetylation degree, and the reaction time course were modelled using a Box–Behnken design. Under optimized conditions, water-soluble COs up to the nonasaccharide were formed in 51% yield and purified to homogeneity. This straightforward approach opens new avenues to determine the complex roles of COs in plants.

scholarly journals Transformation of Construction Cement to a Self-Healing Hybrid Binder

2019 ◽  
Vol 20 (12) ◽  
pp. 2948 ◽  
Author(s):  
Werner E.G. Müller ◽  
Emad Tolba ◽  
Shunfeng Wang ◽  
Qiang Li ◽  
Meik Neufurth ◽  
...  
Keyword(s):  
Soil Bacteria ◽  
Construction Material ◽  
Water Soluble ◽  
The Self ◽  
Average Chain Length ◽  
Self Healing ◽  
Cement Concrete ◽  
Low Concentrations ◽  
Natural Mechanism ◽  
Long Chain

A new biomimetic strategy to im prove the self-healing properties of Portland cement is presented that is based on the application of the biogenic inorganic polymer polyphosphate (polyP), which is used as a cement admixture. The data show that synthetic linear polyp, with an average chain length of 40, as well as natural long-chain polyP isolated from soil bacteria, has the ability to support self-healing of this construction material. Furthermore, polyP, used as a water-soluble Na-salt, is subject to Na+/Ca2+ exchange by the Ca2+ from the cement, resulting in the formation of a water-rich coacervate when added to the cement surface, especially to the surface of bacteria-containing cement/concrete samples. The addition of polyP in low concentrations (<1% on weight basis for the solids) not only accelerated the hardening of cement/concrete but also the healing of microcracks present in the material. The results suggest that long-chain polyP is a promising additive that increases the self-healing capacity of cement by mimicking a bacteria-mediated natural mechanism.

The effect of water-soluble polymers on drug-cyclodextrin complexation

1994 ◽  
Vol 110 (2) ◽  
pp. 169-177 ◽  
Author(s):  
Thorsteinn Loftsson ◽  
Hafrún Frikdriksdóttir ◽  
Anna M. Sigurkdardóttir ◽  
Haruhisa Ueda
Keyword(s):  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Effect Of Water ◽  
Cyclodextrin Complexation

Effect of water-soluble chitosan on the osteoblast function in MC3T3-E1 cells

2015 ◽  
Vol 72 ◽  
pp. 1041-1043 ◽  
Author(s):  
Jian-Wen Hou ◽  
Li Qian ◽  
Jian-Ming Kou ◽  
Cui-Wen Zhang ◽  
Xue-Jun Jia ◽  
...  
Keyword(s):  
Water Soluble ◽  
Osteoblast Function ◽  
Effect Of Water

Nonaqueous Biphasic Hydroformylation of Long Chain Alkenes Catalyzed by Water Soluble Phosphine Rhodium Catalyst with Polyethylene Glycol Instead of Water

2017 ◽  
Vol 148 (1) ◽  
pp. 438-442 ◽  
Author(s):  
Yuanjiang Zhao ◽  
Yanli Liu ◽  
Jianzhang Wei ◽  
Haiyan Fu ◽  
Xueli Zheng ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Rhodium Catalyst ◽  
Water Soluble ◽  
Water Soluble Phosphine ◽  
Long Chain

scholarly journals Nephrotoxicological Effect of Water Soluble Fraction of Bonny Light Crude Oil in Wistar Albino Rats

2019 ◽  
pp. 1-9
Author(s):  
Abraham, Chiedozie Nicholas ◽  
J. Udom, Godwin ◽  
C. Patrick-Iwuanyanwu, Kingsley
Keyword(s):  
Crude Oil ◽  
Soluble Fraction ◽  
Water Soluble ◽  
Albino Rats ◽  
Renal Tubules ◽  
Water Soluble Fraction ◽  
Light Crude Oil ◽  
Range Finding ◽  
Effect Of Water ◽  
Wistar Albino Rats

This study evaluated the Nephrotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO). After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BLCO for 30 and 60days. Data from the study showed that Urea concentration increased significantly (p≤0.05) with increasing dose of BLCO ranging from 14.71 mg/dl in the control to 35.28 mg/dl in the 100% group after 30days and 14.28 mg/dl in the control to 41.08mg/dl in the 100% group after 60days, Creatinine concentration increased significantly (p≤0.05) from 0.22 mg/dl in the control to 0.82mg/dl in the 100% group after 60 days administration while electrolyte (Na, K, Cl) concentration increased significantly (p≤0.05) with increasing dose of BLCO after 60days administration. Histopathological examination of the kidney was characterized by partial partitioning of the glomerular tufts, obliteration of the Bowman’s capsule and distortion of the renal tubules. The findings in this research suggest that WSF of BLCO induced nephrotoxicity.

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