Changes of nitric oxide synthase activity and free methylarginines contents in regenerating rat liver after partial hepatectomy

1997 ◽  
Vol 20 (3) ◽  
pp. 239-246 ◽  
Author(s):  
Young Jin Lee ◽  
Suk Woo Nam ◽  
Dong Wan Seo ◽  
Seong Hoon Ahn ◽  
Young Kwon Ko ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Partial Hepatectomy ◽  
Rat Liver ◽  
Regenerating Rat Liver ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

scholarly journals Measurement of nitric oxide synthase activity in sections of rat liver.

1995 ◽  
Vol 43 (12) ◽  
pp. 1229-1233 ◽  
Author(s):  
S Mehdizadeh ◽  
A O'Farrell ◽  
L Bitensky ◽  
J Weisz ◽  
J Alaghband-Zadeh ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Rat Liver ◽  
Guanylate Cyclase ◽  
Kupffer Cells ◽  
Soluble Guanylate Cyclase ◽  
Reaction Medium ◽  
Guanylate Cyclase Activity ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

In the previous communication we described a histochemical method for measuring soluble guanylate cyclase (sGC) activity in sections of rat liver. In theory, this method could be used to assess nitric oxide synthase (NOS) activity by the increased sGC activity induced by the additional presence of the substrates for NOS activity. We found that this was correct provided that the concentration of the colloid stabilizer in the reaction medium was decreased to just below the concentration required to fully stabilize the guanylate cyclase activity in the sections. This was related to the fact that the site of NOS activity was different from that of the sGC activity in the hepatocytes, so that the NO generated had to diffuse from the Kupffer cells to the hepatocytes as could occur only in partially unstabilized sections. Optimal concentrations of arginine and of NADPH have been determined for demonstrating NOS activity; the increased reaction was shown to be largely inhibited by methyl-arginine.

Effect of KH-305 on the Nitric Oxide Synthase Activity and Erectile Dysfunction in Young Rats

2007 ◽  
Vol 36 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Eun-Jeong Lee ◽  
Hee-Seok Kim ◽  
Byoung-Chul Kim ◽  
Sung-Wan Hwang ◽  
Sung-Yeoun Hwang
Keyword(s):  
Nitric Oxide ◽  
Erectile Dysfunction ◽  
Nitric Oxide Synthase ◽  
Young Rats ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

Inhibition of Nitric Oxide Synthase Activity by Zn2+ Ion

Biochemistry ◽  
1995 ◽  
Vol 34 (46) ◽  
pp. 15091-15095 ◽  
Author(s):  
Anthony Persechini ◽  
Kirk McMillan ◽  
Bettie Sue Siler Masters
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

scholarly journals Time Course of Inducible Nitric Oxide Synthase Activity Following Endotoxin Administration in Dogs

Nitric Oxide ◽  
2001 ◽  
Vol 5 (2) ◽  
pp. 208-211 ◽  
Author(s):  
Jean-Charles Preiser ◽  
Haibo Zhang ◽  
Bernard Vray ◽  
Andreas Hrabak ◽  
Jean-Louis Vincent
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Time Course ◽  
Endotoxin Administration ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity ◽  
Inducible Nitric Oxide

Neuroprotective Effect of Chuk-Me-Sun-Dan on NMDA- and AMPA-Evoked Nitric Oxide Synthase Activity in Mouse Brain

2005 ◽  
Vol 27 (3) ◽  
pp. 499-514 ◽  
Author(s):  
Byung-Soo Koo ◽  
Eun-Gyu Choi ◽  
Jae-Bok Park ◽  
Chang-Ho Cho ◽  
Kang-Hyun Chung ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Mouse Brain ◽  
Neuroprotective Effect ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity
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