Short-time analysis for adjuvant chemotherapy in patients with early-stage bulky cervical carcinoma

2003 ◽  
Vol 15 (2) ◽  
pp. 144-148 ◽  
Author(s):  
Hua Linghu ◽  
Xiao-rong Xu ◽  
Yao-yu Mei ◽  
Jun-ying Tang ◽  
Liang-dan Tang ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Cervical Carcinoma ◽  
Early Stage ◽  
Time Analysis ◽  
Short Time

A modern method of treating initial caries for children using the infltration method

2020 ◽  
Vol 20 (1) ◽  
pp. 4-8
Author(s):  
A. U. Zamurayeva ◽  
Е. T. Supiyeva ◽  
B Sh. Orynbayeva
Keyword(s):  
Pathogenic Bacteria ◽  
Early Stage ◽  
Modern Method ◽  
Modern Technology ◽  
White Spot ◽  
Tooth Decay ◽  
Low Viscosity ◽  
Initial Caries ◽  
Short Time ◽  
Infiltration Method

Relevance. The modern method of infiltration provides an opportunity to stop the spread of pathogenic bacteria and the development of caries at the white spot stage, replacing the destroyed enamel cells with special polymers having low viscosity and high penetrating ability. The stabilization of the process is achieved in a short time with the maximum safety of their tissues. Purpose. Treatment of initial tooth decay in children by infiltration, assessment of the effectiveness and advantages of modern technology. Materials and methods. Clinical examination was carried out according to generally accepted methods. Additionally, a laser diagnostic method was used using the KaVo DIAGNOdent device (Germany). The LLP Dentistry Center «Zhaik Dent» and the LLP «Concept» used the Icon system for the treatment of initial caries and after orthodontic treatment for 25 children with 54 teeth. Results. At the end of tooth treatment with the Icon infiltration method, parents and the child were given recommendations: from the next day, brush your teeth 2 times a day, rinse your mouth regularly after eating, do not drink drinks, products with coloring substances. To monitor the result of treatment, the child was prescribed for reexamination after 7-10 days, after one month, in the following periods – once a year.After working with the material of the Icon system, the authors noted the pronounced effects of the treatment of initial caries by the method of infiltration.Conclusions. 1. The method of infiltration is a modern and promising technology for the treatment of dental caries at an early stage without losing healthy tissues. 2. The Icon infiltration method makes it possible to stop the spread of pathogenic bacteria and develop tooth decay at the white spot stage, replacing the destroyed enamel cells with special polymers having low viscosity and high penetrating ability. 3. The stabilization of the carious process is achieved in a short time with the maximum preservation of the tooth's tissues. 

Immunohistochemical expression of p53, bcl-2, and p21WAF1/CIP1 in early cervical carcinoma: Correlation with clinical outcome

2002 ◽  
Vol 12 (3) ◽  
pp. 290-298 ◽  
Author(s):  
M Graflund ◽  
B Sorbe ◽  
M Karlsson
Keyword(s):  
Survival Rate ◽  
Clinical Outcome ◽  
Cervical Carcinoma ◽  
Early Stage ◽  
Tumor Grade ◽  
Figo Stage ◽  
Immunohistochemical Expression ◽  
Cancer Specific Survival ◽  
Term Survival ◽  
Cervical Carcinomas

Abstract.Graflund M, Sorbe B, Karlsson M. Immunohistochemical expression of p53, bcl-2, and p21 WAF1/CIP1 in early cervical carcinoma: Correlation with clinical outcome.The objective of this study was to assess the value of p53, bcl-2, and p21WAF1/CIP1 immunoreactivity as predictors of pelvic lymph node metastases (LNM), recurrences, and death due to the disease in early stage (FIGO I-II) cervical carcinomas. FIGO stage, type of histopathology, and tumor grade were also evaluated in this series of patients treated by radical hysterectomy (Wertheim-Meigs) between 1965 and 1990. A total of 172 patients were included. A tumor was regarded as positive when more than 30% of the neoplastic cells exhibited immunoreactivity. Positive immunostaining was found in 8.9% for p53, in 43.5% for bcl-2, and in 25.0% for p21WAF1/CIP1. None of them was able to predict LNM or clinical outcome. Presence of LNM, tumor recurrence, and death from disease were significantly associated with the FIGO stage (P = 0.014, P = 0.009, and P = 0.001, respectively). The 5-year cancer-specific survival rate was 91.6% and the overall survival rate was 90.5%. It was concluded that immunohistochemically detected p53, bcl-2, and p21WAF1/CIP1 appeared to be of no predictive value with regard to LNM, tumor recurrences, or long-term survival in early cervical carcinomas.

Systematic review of adjuvant therapy for early stage (epithelial) ovarian cancer

2003 ◽  
Vol 13 (4) ◽  
pp. 395-404 ◽  
Author(s):  
B. Winter-Roach ◽  
L. Hooper ◽  
H. Kitchener
Keyword(s):  
Systematic Review ◽  
Ovarian Cancer ◽  
Adjuvant Chemotherapy ◽  
Adjuvant Therapy ◽  
Early Stage ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Significant Difference ◽  
Well Differentiated ◽  
Platinum Chemotherapy

A systematic review and meta analysis has been undertaken in order to evaluate the effectiveness of adjuvant therapy following surgery for early ovarian cancer. Trials reported since 1990 have been of a higher quality enabling a meta analysis of adjuvant chemotherapy vs adjuvant radiotherapy and a meta analysis of adjuvant chemotherapy vs observation. There was no significant difference between radiotherapy and chemotherapy, though these comprised studies which demonstrated considerable heterogeneity. Chemotherapy did confer significant benefit over observation in terms of both overall and disease free survival. Except for women in whom adequate surgical staging has revealed well differentiated disease confined to one or both ovaries with intact capsule, platinum chemotherapy should be offered to reduce risk of recurrence.

scholarly journals Prognostic and Predictive Markers of Benefit from Adjuvant Chemotherapy in Early-Stage Non-small Cell Lung Cancer

2009 ◽  
Vol 4 (7) ◽  
pp. 891-910 ◽  
Author(s):  
Ana Belén Custodio ◽  
José Luis González-Larriba ◽  
Jana Bobokova ◽  
Antonio Calles ◽  
Rafael Álvarez ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Adjuvant Chemotherapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Small Cell ◽  
Predictive Markers ◽  
Small Cell Lung ◽  
Prognostic And Predictive Markers

scholarly journals Early-stage, high-grade neuroendocrine cervical carcinoma

2021 ◽  
Vol 31 (8) ◽  
pp. 1179-1183
Author(s):  
Gloria Salvo ◽  
Preetha Ramalingam ◽  
Priya Bhosale ◽  
Michael Frumovitz
Keyword(s):  
Cervical Carcinoma ◽  
Early Stage ◽  
High Grade

Adenocarcinoma as an independent risk factor for early-stage intermediate-risk cervical carcinoma

2011 ◽  
Vol 120 ◽  
pp. S104-S105
Author(s):  
C. Mathews ◽  
S. Goodrich ◽  
R. Farrell ◽  
C. DeSimone ◽  
L. Seamon ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cervical Carcinoma ◽  
Independent Risk Factor ◽  
Early Stage ◽  
Intermediate Risk

scholarly journals Cognitive functioning after adjuvant chemotherapy and/or radiotherapy for early-stage breast carcinoma

Cancer ◽  
2005 ◽  
Vol 104 (11) ◽  
pp. 2499-2507 ◽  
Author(s):  
Kristine A. Donovan ◽  
Brent J. Small ◽  
Michael A. Andrykowski ◽  
Frederick A. Schmitt ◽  
Pamela Munster ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Breast Carcinoma ◽  
Cognitive Functioning ◽  
Early Stage
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