Metastatic breast cancer of HER2 scored 2+ by IHC and HER2 gene amplification assayed by FISH has a good response to single agent therapy with trastuzumab: A case report

Masato Takahashi; Ken-ichi Inoue; Ryoichi Goto; Motoshi Tamura; Kazunori Taguchi; Hiromasa Takahashi; Hiroaki Suzuki; Katsushige Yamashiro; Masami Ogita

doi:10.1007/bf02967645

Metastatic breast cancer of HER2 scored 2+ by IHC and HER2 gene amplification assayed by FISH has a good response to single agent therapy with trastuzumab: A case report

Breast Cancer ◽

10.1007/bf02967645 ◽

2003 ◽

Vol 10 (2) ◽

pp. 170-174 ◽

Cited By ~ 3

Author(s):

Masato Takahashi ◽

Ken-ichi Inoue ◽

Ryoichi Goto ◽

Motoshi Tamura ◽

Kazunori Taguchi ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Case Report ◽

Gene Amplification ◽

Single Agent ◽

Metastatic Breast ◽

Her2 Gene ◽

Single Agent Therapy ◽

Her2 Gene Amplification

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A case of metastatic Breast Cancer with HER2 gene amplification that responded completely to single agent trastuzumab

Breast Cancer ◽

10.2325/jbcs.13.374 ◽

2006 ◽

Vol 13 (4) ◽

pp. 374-377 ◽

Cited By ~ 4

Author(s):

Yasuhiro Tsutani ◽

Shozo Ohsumi ◽

Kenjiro Aogi ◽

Naruto Taira ◽

Masaaki Kataoka ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Gene Amplification ◽

Single Agent ◽

Metastatic Breast ◽

Her2 Gene ◽

Her2 Gene Amplification

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HER2 Gene Amplification by Fluorescence In Situ Hybridization(FISH) as a Predictor of Response to Trastuzumab in Metastatic Breast Cancer

Clinical Breast Cancer ◽

10.1016/s1526-8209(11)70109-4 ◽

2000 ◽

Vol 1 (2) ◽

pp. 105-106

Keyword(s):

Breast Cancer ◽

In Situ Hybridization ◽

Metastatic Breast Cancer ◽

Fluorescence In Situ Hybridization ◽

Gene Amplification ◽

Metastatic Breast ◽

Her2 Gene ◽

Her2 Gene Amplification

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Methodology matters – prognostic significance of HER2 protein expression versus HER2 gene amplification in metastatic breast cancer

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(08)71791-9 ◽

2008 ◽

Vol 6 (9) ◽

pp. 160

Author(s):

N. Todorovic-Rakovic ◽

D. Jovanovic ◽

Z. Neskovic-Konstantinovic ◽

D. Nikolic-Vukosavljevic

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Protein Expression ◽

Gene Amplification ◽

Prognostic Significance ◽

Metastatic Breast ◽

Her2 Gene ◽

Her2 Protein ◽

Her2 Gene Amplification

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Correlation of HER2 gene amplification, HER2 and EGFR expression (protein and mRNA) with lapatinib efficacy in women with metastatic breast cancer

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.1007 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 1007-1007 ◽

Cited By ~ 5

Author(s):

M. F. Press ◽

R. S. Finn ◽

A. Di Leo ◽

D. A. Cameron ◽

C. E. Geyer ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Gene Amplification ◽

Metastatic Breast ◽

Her2 Gene ◽

Egfr Expression ◽

Her2 Gene Amplification

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Prognostic value of HER2 gene amplification detected by chromogenic in situ hybridization (CISH) in metastatic breast cancer

Experimental and Molecular Pathology ◽

10.1016/j.yexmp.2007.01.002 ◽

2007 ◽

Vol 82 (3) ◽

pp. 262-268 ◽

Cited By ~ 19

Author(s):

Nataša Todorović-Raković ◽

Danica Jovanović ◽

Zora Nešković-Konstantinović ◽

Dragica Nikolić-Vukosavljević

Keyword(s):

Breast Cancer ◽

In Situ Hybridization ◽

Metastatic Breast Cancer ◽

Gene Amplification ◽

Prognostic Value ◽

Metastatic Breast ◽

Her2 Gene ◽

Her2 Gene Amplification ◽

Chromogenic In Situ Hybridization

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A meta-analysis of combination therapy versus single-agent therapy in anthracycline- and taxane-pretreated metastatic breast cancer: results from nine randomized Phase III trials

OncoTargets and Therapy ◽

10.2147/ott.s101423 ◽

2016 ◽

Vol Volume 9 ◽

pp. 4061-4074 ◽

Cited By ~ 6

Author(s):

Fengchun Zhang ◽

Xiaobo Wu ◽

Chun Hu ◽

Zhiying Zhang ◽

Le Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Combination Therapy ◽

Meta Analysis ◽

Single Agent ◽

Metastatic Breast ◽

Phase Iii ◽

Single Agent Therapy ◽

Phase Iii Trials

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Open label, comparative, randomised, multicentre study of trastuzumab given with docetaxel versus sequential single agent therapy with trastuzumab followed by docetaxel as first-line treatment for Her2neu+++ metastatic breast cancer patients

http://isrctn.org/> ◽

10.1186/isrctn13770586 ◽

2012 ◽

Author(s):

J.G.M. Klijn

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Single Agent ◽

Metastatic Breast ◽

Line Treatment ◽

Breast Cancer Patients ◽

First Line ◽

Open Label ◽

Single Agent Therapy ◽

First Line Treatment

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Complete Response to Single-agent Palbociclib in Metastatic Breast Cancer: A Case Report

Clinical Breast Cancer ◽

10.1016/j.clbc.2017.12.008 ◽

2018 ◽

Vol 18 (3) ◽

pp. e277-e280 ◽

Cited By ~ 1

Author(s):

Sri Lakshmi Hyndavi Yeruva ◽

Mehrbod Som Javadi ◽

Vered Stearns

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Case Report ◽

Single Agent ◽

Metastatic Breast ◽

Complete Response

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Determination of HER2 Gene Amplification by Fluorescence In situ Hybridization and Concordance with the Clinical Trials Immunohistochemical Assay in Women with Metastatic Breast Cancer Evaluated for Treatment with Trastuzumab

Breast Cancer Research and Treatment ◽

10.1007/s10549-004-6275-8 ◽

2005 ◽

Vol 93 (1) ◽

pp. 3-11 ◽

Cited By ~ 105

Author(s):

Noël Dybdal ◽

Grazyna Leiberman ◽

Steven Anderson ◽

Bryan McCune ◽

Alex Bajamonde ◽

...

Keyword(s):

Breast Cancer ◽

Clinical Trials ◽

In Situ Hybridization ◽

Metastatic Breast Cancer ◽

Metastatic Breast ◽

Her2 Gene ◽

Immunohistochemical Assay ◽

Her2 Gene Amplification

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Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer

Breast Cancer Research ◽

10.1186/bcr574 ◽

2003 ◽

Vol 5 (2) ◽

Cited By ~ 38

Author(s):

Carlos L Arteaga

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Single Agent ◽

Metastatic Breast ◽

First Line ◽

Single Agent Therapy

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