Human Tuberculosis and the Bovine Type of Tubercle Bacillus in Eire

1940 ◽  
Vol 15 (10) ◽  
pp. 683-693 ◽  
Author(s):  
Cecil Mushatt
Keyword(s):  
Tubercle Bacillus ◽  
Bovine Type

STUDIES IN THE VARIABILITY OF TUBERCLE BACILLI: I. A RAPID-GROWING BOVINE TYPE

1931 ◽  
Vol 4 (4) ◽  
pp. 389-398 ◽  
Author(s):  
Guilford B. Reed ◽  
Christine E. Rice
Keyword(s):  
Related Species ◽  
Tubercle Bacillus ◽  
Solid Media ◽  
Fluid Media ◽  
Acid Fluid ◽  
Bovine Type

Variability studies have been carried out on a considerable series of cultures of tubercle bacilli and related species of acid-fast bacteria. The present paper deals with a rapid-growing strain of the bovine tubercle bacillus. The results are in conformity with claims recently made by Petroff that certain types of tubercle bacilli undergo dissociation.It is shown that this avirulent, rapid-growing strain consists of R types which appear to be stable in acid fluid media and more or less stable on solid media. Rapid transfers through strongly alkaline fluids or growth in large volumes of similar media result in appreciable dissociation into S types. The S types were unstable, particularly in acid fluid media, and readily reverted to the R form.

scholarly journals Non-pulmonary tuberculosis in England and in Wales. Account of a group investigation undertaken during the years 1943 to 1954

1949 ◽  
Vol 47 (4) ◽  
pp. 337-359 ◽  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Relative Frequency ◽  
Tubercle Bacillus ◽  
Human Type ◽  
Laboratory Workers ◽  
Bovine Type

1. The present inquiry was designed to provide information on the relative frequency of infection in non-pulmonary tuberculosis with the human and bovine type of tubercle bacillus throughout the whole of England. A total of 149 pathologists at 120 collecting centres and 32 bacteriologists at 27 typing centres took part in the scheme. Two questionnaires relating to each patient were used, one to be filled in by the laboratory workers and one by the Tuberculosis Officer or other responsible official.1. Tubercle bacilli were isolated and typed from 112 patients in Wales. of these strains, 19 or 17·0 % belonged to the bovine and 93 or 83 % to the human type (Table 16).

TYPES OF TUBERCLE BACILLI IN HUMAN TUBERCULOSIS

1932 ◽  
Vol 7 (6) ◽  
pp. 606-616
Author(s):  
R. M. Price
Keyword(s):  
Bovine Tuberculosis ◽  
Tubercle Bacillus ◽  
Adult Group ◽  
Human Type ◽  
Group 6 ◽  
Bovine Type

Four hundred and thirty-six cases of clinical tuberculosis were investigated with a view to ascertaining the types of the infecting organism. In this series of cases, 268 were children under 14 years of age, and 168 adults, 15 years and over. Both medical and surgical cases were studied. In the juvenile group, 230 patients proved to be infected with the human type, and 38, or 14.1%, with the bovine type of the tubercle bacillus. In the adult group 6, or 3.5%, proved to be infected with the bovine type, the remaining 162 cases with the human type of the tubercle bacillus. Bovine tuberculosis in man is milk-borne and preventable.

scholarly journals THE SPECIFIC CYTOTOXIC ACTION OF TUBERCULIN IN TISSUE CULTURE

1931 ◽  
Vol 54 (3) ◽  
pp. 387-397 ◽  
Author(s):  
Joseph D. Aronson
Keyword(s):  
Bone Marrow ◽  
Tissue Culture ◽  
Guinea Pigs ◽  
Toxic Action ◽  
Cytotoxic Action ◽  
Tubercle Bacillus ◽  
Culture Methods ◽  
Bovine Type

Tuberculin from the human and from the bovine type of tubercle bacilli inhibits the growth of cells from explants of bone marrow, spleen and testes of tuberculous guinea pigs, and is toxic for these cells, but has no effect on explants of the same tissues from non-tuberculous animals. "Tuberculin" from other acid-fast bacteria has no inhibitory or toxic action on explants of tissues from either tuberculous or non-tuberculous guinea pigs. Tuberculins from the avian, bovine and human types of tubercle bacillus as well as "tuberculin" prepared from the Duval and from the Kedrowsky strains of M. leprae inhibit the growth of the cells of explants of the spleen and bone marrow of tuberculous fowls and are toxic for these cells, but have no effect on the explants from tissues of non-tuberculous chickens. "Tuberculins" from other acid-fast bacteria have no effect on the growth of explants of tissues from tuberculous or from non-tuberculous fowls. Tissue culture methods indicate that the sensitivity of tuberculous tissues to tuberculin is inherent in the cell, and that it cannot be passively transferred.

PHTHISIS PULMONALIS DUE TO THE BOVINE TYPE OF TUBERCLE BACILLUS

The Lancet ◽  
1933 ◽  
Vol 221 (5713) ◽  
pp. 399-403 ◽  
Author(s):  
A Stanley Griffith ◽  
W.T Munro
Keyword(s):  
Tubercle Bacillus ◽  
Bovine Type

The serology of the bovine type of the tubercle bacillus

Tubercle ◽  
1925 ◽  
Vol 7 (3) ◽  
pp. 105-111 ◽  
Author(s):  
W.M. Cumming
Keyword(s):  
Tubercle Bacillus ◽  
Bovine Type
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