Analysis of clinical effects on 211 cases with middle and late stage lung cancer

1995 ◽  
Vol 1 (4) ◽  
pp. 249-254
Author(s):  
Yu-ling Xin
Keyword(s):  
Lung Cancer ◽  
Late Stage ◽  
Clinical Effects ◽  
Stage Lung Cancer

scholarly journals Low prognostic nutrition index predicts poorer quality of life in late-stage lung cancer

2020 ◽  
Vol 9 (6) ◽  
pp. 3976-3984
Author(s):  
Zhaohui Zhang ◽  
Aiping Chen ◽  
Fenglan Xie ◽  
Xuefei Li ◽  
Guoxiang Hu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Late Stage ◽  
Prognostic Nutrition Index ◽  
Stage Lung Cancer

Late-stage lung cancer patient preferences about chemotherapy treatment adverse side effects.

2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 93-93
Author(s):  
K. M Islam ◽  
June Ryan ◽  
Ann Fetrick ◽  
Apar Kishor Ganti
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Adverse Events ◽  
Late Stage ◽  
Treatment Success ◽  
Chemotherapy Treatment ◽  
Cancer Centers ◽  
Definition Of ◽  
Stage Lung Cancer

93 Background: Patients’ preferences regarding treatment adverse events are not systematically considered when choosing a treatment for stage lung cancer. Further, there is no clinical guide for patients or physicians on how to integrate patient preferences of adverse events in treatment and care decisions. Although it is assumed that most cancer patients prefer either an active or a shared role in decision making, particularly in late stage cancers. Our specific aim of this abstract is: Aim: Determine whether individual patients’ preferences, characteristics, and treatment experiences affect the meaning of chemotherapy treatment success. Methods: We have completed two years of our three-year research using a mixed method study design, which includes focus groups, cross-sectional, prospective, and randomized experimental designs. We initially selected three cancer centers in Nebraska and one in South Dakota for patient and provider recruitment. Currently, we have six cancer centers participating in this multi-center Patient Centered Outcomes Research. Results: Four focus groups were conducted with 36 participants that included patients, family members and caregivers and oncology providers. Patients and caregivers confirmed that survival alone is not their measure of lung cancer treatment success Definition of treatment success should emphasize effective clinical guidance throughout treatment, symptom management, functionality, and quality of life Definition of treatment success evolves over time, appearing to be linked to patients’ experiences with chemotherapy. Participants advocated for better patient-provider communication practices as well as the expanded use of patient navigation and new patient orientation programs. Conclusions: Late stage lung cancer patients have definite opinions about the impact of adverse treatment effects on their quality of life.

An Actuarial Approach to Comparing Early Stage and Late Stage Lung Cancer Mortality and Survival

2010 ◽  
Vol 13 (1) ◽  
pp. 33-46 ◽  
Author(s):  
Sara W. Goldberg ◽  
James L. Mulshine ◽  
Dale Hagstrom ◽  
Bruce S. Pyenson
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Late Stage ◽  
Early Stage ◽  
Lung Cancer Mortality ◽  
Actuarial Approach ◽  
Stage Lung Cancer

scholarly journals The Prognostic Significance of PD1 and PDL1 Gene Expression in Lung Cancer: A Meta-Analysis

2021 ◽  
Vol 11 ◽  
Author(s):  
Chih-Hao Chang ◽  
Arthur Chun-Chieh Shih ◽  
Ya-Hsuan Chang ◽  
Hsuan‐Yu Chen ◽  
Ying-Ting Chao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lung Cancer ◽  
Cell Death ◽  
Programmed Cell Death ◽  
Immune Checkpoint ◽  
Late Stage ◽  
Early Stage ◽  
Meta Analysis ◽  
Risk Of Relapse ◽  
Stage Lung Cancer

BackgroundImmune checkpoint blockade therapy represents an extraordinary advance in lung cancer treatment. It is important to determine the expression of immune checkpoint genes, such as programmed cell death 1 (PD1) and programmed cell death-ligand 1 (PDL1), to develop immunotherapeutic strategies. The aim of this study was to explore the association between PD1 and PDL1 gene expression and prognoses and outcomes in lung cancer.MethodsThis meta-analysis analyzed 1,251 patients from eight different microarray gene expression datasets and were evaluated for their prognostic implications and verified using another independent research.ResultsThe mean expression levels of PDL1 in adenocarcinoma (AD) and squamous cell carcinoma (SC) were significantly higher in patients who died than in patients who did not. There was a trend toward incremental increases in PD1 and PDL1 expression significantly decreasing the risk of relapse and death among AD patients (HR = 0.69; 95% CI = 0.53 ~ 0.91; HR = 0.68; 95% CI = 0.54 ~ 0.84, respectively) and SC patients (HR = 0.53; 95% CI = 0.32 ~ 0.89; HR = 0.78; 95% CI = 0.57 ~ 1.00 respectively), as early-stage patients in this study were more likely to have high expression of both PD1 and PDL1 than late-stage patients (P-trend < 0.05). In contrast, late-stage SC patients expressing one or more of the genes at a high level had a significantly elevated risk of relapse (HR = 1.51; 95% CI = 1.07 ~ 2.11) and death (HR = 1.41; 95% CI = 1.08 ~ 1.84). This result was consistent with the validation data set.ConclusionThese findings indicate that high expression of PD1 and PDL1 is associated with superior outcome in early-stage lung cancer but an adverse outcome in late-stage lung cancer. The expression levels of PD1 and PDL1 individually or jointly are potential prognostic factors for predicting patient outcomes in lung cancer.

Caregivers’ attitudes toward promoting exercise among patients with late-stage lung cancer

2015 ◽  
Vol 13 (11) ◽  
pp. 392-398 ◽  
Author(s):  
Lori Rhudy ◽  
Ann Marie Dose ◽  
Jeffrey Basford ◽  
Joan Griffin ◽  
Andrea Cheville
Keyword(s):  
Lung Cancer ◽  
Late Stage ◽  
Stage Lung Cancer

scholarly journals Management of Anorexia-Cachexia in Late-Stage Lung Cancer Patients

2012 ◽  
Vol 14 (6) ◽  
pp. 397-402 ◽  
Author(s):  
Catherine Del Ferraro ◽  
Marcia Grant ◽  
Marianna Koczywas ◽  
Laura A. Dorr-Uyemura
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Late Stage ◽  
Lung Cancer Patients ◽  
Stage Lung Cancer
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