Role of quality assessment in improving red blood cell transfusion practice

1997 ◽  
Vol 166 (1) ◽  
pp. 16-19 ◽  
Author(s):  
G. Joshi ◽  
M. McCarroll ◽  
P. O’Rourke ◽  
F. Coffey
Keyword(s):  
Blood Cell ◽  
Quality Assessment ◽  
Red Blood Cell ◽  
Transfusion Practice ◽  
Red Blood Cell Transfusion

scholarly journals Safety of Red Blood Cell Transfusion Using Small Central Lines in Neonates: An in vitro Non-inferiority Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Flavia Rosa-Mangeret ◽  
Sophie Waldvogel-Abramowski ◽  
Riccardo E. Pfister ◽  
Olivier Baud ◽  
Sébastien Fau
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Transfusion Practice ◽  
Red Blood Cell Transfusion ◽  
Central Lines ◽  
Catheter Occlusion ◽  
Prospective Assessment ◽  
Secondary Endpoints ◽  
Central Catheters

Aim: This study aimed to investigate the safety of transfusing red blood cell concentrates (RBCCs) through small [24 gauge (24G)] and extra-small [28 gauge [28G)] peripherally inserted central catheters (PICCs), according to guidelines of transfusion practice in Switzerland.Methods: We performed a non-inferiority in vitro study to assess the safety of transfusing RBCC for 4 h at a 4 ml/h speed through 24G silicone and 28G polyurethane PICC lines, compared with a peripheral 24G short catheter. The primary endpoint was hemolysis percentage. Secondary endpoints were catheter occlusion, inline pressure, and potassium and lactate values.Results: For the primary outcome, hemolysis values were not statistically different among catheter groups (0.06% variation, p = 0.95) or over time (2.75% variation, p = 0.72). The highest hemolysis values in both 24G and 28G PICCs were below the non-inferiority predefined margin. We did not observe catheter occlusion. Inline pressure varied between catheters but followed the same pattern of rapid increase followed by stabilization. Potassium and lactate measurements were not statistically different among tested catheters (0.139% variation, p = 0.98 for potassium and 0.062%, p = 0.96 for lactates).Conclusions: This study shows that RBCC transfusion performed in vitro through 24G silicone and 28G polyurethane PICC lines is feasible without detectable hemolysis or pressure concerns. Also, it adds that, concerning hemolysis, transfusion of RBCC in small and extra-small PICC lines is non-inferior to peripheral short 24G catheters. Clinical prospective assessment in preterm infants is needed to confirm these data further.

Canine red blood cell transfusion practice

1996 ◽  
Vol 32 (4) ◽  
pp. 303-311 ◽  
Author(s):  
MB Callan ◽  
DA Oakley ◽  
FS Shofer ◽  
U Giger
Keyword(s):  
Adverse Events ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Transfusion Practice ◽  
Red Blood Cell Transfusion ◽  
Ineffective Erythropoiesis ◽  
Packed Red Blood Cells ◽  
The Mean ◽  
Rbc Transfusion

Red blood cell (RBC) transfusions in 307 dogs were reviewed. A total of 658 units of RBCs, including 474 (72%) units of packed red blood cells (PRBCs) and 184 (28%) units of whole blood (WB), were administered. Reasons for transfusion included hemorrhage (n = 222), hemolysis (n = 43), and ineffective erythropoiesis (n = 42). The mean pretransfusion packed cell volume (PCV) of dogs with hemolysis (13%) was significantly lower (p less than 0.0001) than the mean pretransfusion PCVs of dogs with hemorrhage (21%) or ineffective erythropoiesis (18%). The mean total volume of PRBCs transfused was significantly greater (p less than 0.03) in dogs with hemolysis. Overall, 187 (61%) of 307 dogs were discharged from the hospital. Cause of anemia, pretransfusion PCV, and total volume of blood administered did not appear to influence survival. However, the mean adjusted posttransfusion PCV of dogs with hemorrhage was significantly higher (p less than 0.001) in dogs that survived. Possible adverse events were observed during or shortly after RBC transfusion in 10 (3.3%) dogs; all reactions were mild and self-limiting, and none were hemolytic.

Methodologic quality assessment of red blood cell transfusion guidelines and the evidence base of more restrictive transfusion thresholds

Transfusion ◽  
2015 ◽  
Vol 56 (2) ◽  
pp. 472-480 ◽  
Author(s):  
Hans Van Remoortel ◽  
Emmy De Buck ◽  
Tessa Dieltjens ◽  
Nele S. Pauwels ◽  
Veerle Compernolle ◽  
...  
Keyword(s):  
Blood Cell ◽  
Quality Assessment ◽  
Red Blood Cell ◽  
Evidence Base ◽  
Red Blood Cell Transfusion ◽  
Restrictive Transfusion ◽  
Methodologic Quality ◽  
Transfusion Guidelines
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