The role of ascites and phospholipase a2 on peritoneal permeability changes in acute experimental pancreatitis

1990 ◽  
Vol 6 (1) ◽  
pp. 71-79
Author(s):  
Conny Svensson ◽  
Rune Sjödahl ◽  
Ingela Lilja ◽  
Ingemar Ihse
Keyword(s):  
Phospholipase A2 ◽  
Experimental Pancreatitis ◽  
Acute Experimental Pancreatitis ◽  
Permeability Changes ◽  
Peritoneal Permeability

The role of calcitonin in hypocalcemia in acute experimental pancreatitis

1981 ◽  
Vol 37 (5) ◽  
pp. 531-532
Author(s):  
P. D. Broulík ◽  
J. Škrha ◽  
V. Pacovský
Keyword(s):  
Experimental Pancreatitis ◽  
Acute Experimental Pancreatitis

scholarly journals The potential role of kinesin and dynein in Golgi scattering and cytoplasmic vacuole formation during acute experimental pancreatitis

Cell Research ◽  
2010 ◽  
Vol 20 (5) ◽  
pp. 599-602 ◽  
Author(s):  
Ina A Weber ◽  
Igor Buchwalow ◽  
Daniela Hahn ◽  
Wolfram Domschke ◽  
Markus M Lerch ◽  
...  
Keyword(s):  
Potential Role ◽  
Experimental Pancreatitis ◽  
Cytoplasmic Vacuole ◽  
Acute Experimental Pancreatitis ◽  
Vacuole Formation

The role of endogenous and exogenous corticosteroids in the pathogenesis of acute experimental pancreatitis

Pancreatology ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. S9
Author(s):  
Balázs Kui ◽  
Zsolt Balla ◽  
Eszter S. Kormányos ◽  
Béla Iványi ◽  
Péter Hegyi ◽  
...  
Keyword(s):  
Experimental Pancreatitis ◽  
Acute Experimental Pancreatitis

Pathophysiological role of platelets in acute experimental pancreatitis: influence of endothelin A receptor blockade

2006 ◽  
Vol 327 (3) ◽  
pp. 485-492 ◽  
Author(s):  
Dirk Uhlmann ◽  
Heike Lauer ◽  
Frederik Serr ◽  
Stefan Ludwig ◽  
Andrea Tannapfel ◽  
...  
Keyword(s):  
Experimental Pancreatitis ◽  
Receptor Blockade ◽  
Acute Experimental Pancreatitis ◽  
Endothelin A Receptor ◽  
Pathophysiological Role ◽  
Endothelin A

Increased peritoneal permeability in acute experimental pancreatitis

1989 ◽  
Vol 4 (1) ◽  
pp. 91-98 ◽  
Author(s):  
Conny Svensson ◽  
Rune Sjödahl ◽  
Christer Tagesson ◽  
Ingemar Ihse
Keyword(s):  
Experimental Pancreatitis ◽  
Acute Experimental Pancreatitis ◽  
Peritoneal Permeability

Inhibition of Nitric Oxide Synthase Reverses Permeability Changes in a Mouse Model of Acute Peritonitis

2005 ◽  
Vol 25 (3_suppl) ◽  
pp. 11-14 ◽  
Author(s):  
Jie Ni ◽  
Yvette Cnops ◽  
Rachel M. McLoughlin ◽  
Nicholas Topley ◽  
Olivier Devuyst
Keyword(s):  
Nitric Oxide ◽  
Mouse Model ◽  
Molecular Mechanisms ◽  
Acute Peritonitis ◽  
Permeability Changes ◽  
Peritoneal Permeability ◽  
Synthase Inhibitor ◽  
Oxide Synthase ◽  
Sodium Sieving

Acute peritonitis is the most frequent complication of peritoneal dialysis. Previous studies have suggested a major role for nitric oxide (NO) in the permeability changes and loss of ultrafiltration induced by acute peritonitis. In this study, we further investigated the potential role of NO in a mouse model of peritonitis induced by Escherichia coli lipopolysaccharide (LPS). A 2-hour peritoneal equilibration test was performed in control and LPS-treated mice using 7% glucose dialysate supplemented or not with the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME). The levels of NO metabolites in the dialysate were maximal 18 hours after LPS injection. At that time, acute peritonitis induced by LPS was reflected by an increased recruitment of leukocytes, an increased intraperitoneal release of interleukin-6, a significant increase in the peritoneal permeability for small solutes, a loss of sodium sieving, and a loss of ultrafiltration in comparison with controls. Addition of L-NAME in LPS-treated mice significantly reversed permeability modifications and prevented the release of NO metabolites into the dialysate. These results confirm that increased NO mediates permeability modifications during acute peritonitis, and illustrate the potential of mouse models to investigate the molecular mechanisms regulating peritoneal permeability.

THE ROLE OF PANCREATIC PHOSPHOLIPASE A2 IN EXPERIMENTAL PANCREATITIS

Pancreas ◽  
2006 ◽  
Vol 33 (4) ◽  
pp. 493
Author(s):  
M. Ruthenb??rger ◽  
J. Mayerle ◽  
B. Brandt-Nedelev ◽  
I. Jaroscakova ◽  
T. Wartmann ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Experimental Pancreatitis ◽  
Pancreatic Phospholipase ◽  
Pancreatic Phospholipase A2

Long-term ethanol ingestion causes an increase of phospholipase A2 activity in acute experimental pancreatitis in rats

1986 ◽  
Vol 41 (4) ◽  
pp. 362-366 ◽  
Author(s):  
O.Juhani Rämö ◽  
Tom Schröder ◽  
Timo Kuusi ◽  
Pauli Puolakkainen ◽  
Anu Mäkelä ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Experimental Pancreatitis ◽  
Ethanol Ingestion ◽  
Acute Experimental Pancreatitis ◽  
Phospholipase A2 Activity
Sign in / Sign up

Export Citation Format

Share Document