Zinc, iron, vitamin E, and erythrocyte stability in the rat

1989 ◽  
Vol 23 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Ian R. Record ◽  
Sally E. MacQueen ◽  
Ivor E. Dreosti
Keyword(s):  
Vitamin E ◽  
Erythrocyte Stability

scholarly journals Glutathione peroxidase activity and erythrocyte stability in calves differing in selenium and vitamin E status

1968 ◽  
Vol 46 (2) ◽  
pp. 345-355 ◽  
Author(s):  
R. C. Siddons ◽  
C. F. Mills
Keyword(s):  
Vitamin E ◽  
Glutathione Peroxidase ◽  
Peroxidase Activity ◽  
Dietary Vitamin ◽  
Plasma Vitamin ◽  
Glutathione Peroxidase Activity ◽  
Bull Calves ◽  
Plasma Vitamin E ◽  
Erythrocyte Stability ◽  
Vitamin E Status

1. Glutathione peroxidase activity (EC1.11.1.9) and erythrocyte stability were measured in Friesian bull calves which were given for 36 weeks semi-purified diets either adequate or low in selenium or vitamin E or both.2. Dietary Se or vitamin E content had no effect on growth rate and haematological vaiues. None of the calves exhibited clinical deficiency symptoms and serum aspartate amino transferase (EC 2.6.1.1) and creatine phosphokinase (EC 2.7.3.2) activities remained normal. Heart and skeletal muscles of all calves appeared macroscopically and microscopically normal at autopsy.3. Glutathione peroxidase activity in plasma, blood and other tissues, except the testis, was significantly lower in calves receiving low dietary Se but was independent of dietary vitamin E content.4. Plasma vitamin E levels decreased rapidly and to very low levels in calves given low vitamin E diets irrespective of the Se content of the diet.5. A low dietary vitamin E intake increased the susceptibility of erythrocytes to auto- and peroxidative haemolysis whereas a low Se intake in the presence of adequate vitamin E did not. However, erythrocytes from calves receiving low Se and low vitamin E were more susceptible to peroxidative haemolysis than erythrocytes from calves receiving low vitamin E and adequate Se. The effect of dietary vitamin E content on osmotic haemolysis induced by hypotonic saline was variable.6. The results suggest that measurement of blood glutathione peroxidase activity and the susceptibility of erythrocytes to auto- or peroxidative haemolysis could be used for the differential diagnosis of subclinical Se and vitamin E deficiency in ruminants.

1120: Citrate and Vitamin E Blunt the SWL-Induced Free Radical Surge in an In-Vitro MDCK Cell Culture Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 295-295
Author(s):  
Fernando C. Delvecchio ◽  
Ricardo M. Brizuela ◽  
Karen J. Byer ◽  
W. Patrick Springhart ◽  
Saeed R. Khan ◽  
...  
Keyword(s):  
Cell Culture ◽  
Free Radical ◽  
Vitamin E ◽  
Mdck Cell ◽  
Cell Culture Model ◽  
Culture Model
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