Comparison of measurements of total lung capacity by a computer-aided radiographic method with body plethysmography in a clinical setting

1986 ◽  
Vol 2 (3) ◽  
pp. 163-166
Author(s):  
George E. Bokinsky
Keyword(s):  
Clinical Setting ◽  
Total Lung Capacity ◽  
Body Plethysmography ◽  
Lung Capacity ◽  
Radiographic Method ◽  
Computer Aided

Ventilation Heterogeneity in Asthma and COPD: The Value of the Poorly Communicating Fraction as the Ratio of Total Lung Capacity to Alveolar Volume

Respiration ◽  
2021 ◽  
pp. 1-7
Author(s):  
Roberta Pisi ◽  
Marina Aiello ◽  
Luigino Calzetta ◽  
Annalisa Frizzelli ◽  
Veronica Alfieri ◽  
...  
Keyword(s):  
Total Lung Capacity ◽  
Airflow Obstruction ◽  
Diffusing Capacity ◽  
Body Plethysmography ◽  
Alveolar Volume ◽  
Asthmatic Patients ◽  
Lung Capacity ◽  
Copd Patients ◽  
Ventilation Heterogeneity ◽  
Patient Groups

<b><i>Background:</i></b> The ventilation heterogeneity (VH) is reliably assessed by the multiple-breath nitrogen washout (MBNW), which provides indices of conductive (<i>S</i><sub>cond</sub>) and acinar (<i>S</i><sub>acin</sub>) VH as well as the lung clearance index (LCI), an index of global VH. VH can be alternatively measured by the poorly communicating fraction (PCF), that is, the ratio of total lung capacity by body plethysmography to alveolar volume from the single-breath lung diffusing capacity measurement. <b><i>Objectives:</i></b> Our objective was to assess VH by PCF and MBNW in patients with asthma and with COPD and to compare PCF and MBNW parameters in both patient groups. <b><i>Method:</i></b> We studied 35 asthmatic patients and 45 patients with COPD. Each patient performed spirometry, body plethysmography, diffusing capacity, and MBNW test. <b><i>Results:</i></b> Compared to COPD patients, asthmatics showed a significantly lesser degree of airflow obstruction and lung hyperinflation. In asthmatic patients, both PCF and LCI and <i>S</i><sub>acin</sub> values were significantly lower than the corresponding ones of COPD patients. In addition, in both patient groups, PCF showed a positive correlation with LCI (<i>p</i> &#x3c; 0.05) and <i>S</i><sub>acin</sub> (<i>p</i> &#x3c; 0.05), but not with <i>S</i><sub>cond</sub>. Lastly, COPD patients with PCF &#x3e;30% were highly likely to have a value ≥2 of the mMRC dyspnea scale. <b><i>Conclusions:</i></b> These results showed that PCF, a readily measure derived from routine pulmonary function testing, can provide a comprehensive measure of both global and acinar VH in asthma and in COPD patients and can be considered as a comparable tool to the well-established MBNW technique.

scholarly journals An accurate and rapid radiographic method of determining total lung capacity

Thorax ◽  
1972 ◽  
Vol 27 (2) ◽  
pp. 163-168 ◽  
Author(s):  
R. B. Reger ◽  
A. Young ◽  
W. K. C. Morgan
Keyword(s):  
Total Lung Capacity ◽  
Lung Capacity ◽  
Radiographic Method

Rapid Computer-Aided Radiographic Calculation of Total Lung Capacity (TLC)

Radiology ◽  
1975 ◽  
Vol 117 (2) ◽  
pp. 269-273 ◽  
Author(s):  
William V. Glenn ◽  
Reginald Greene
Keyword(s):  
Total Lung Capacity ◽  
Lung Capacity ◽  
Computer Aided

scholarly journals Estimation of total lung capacity from chest radiography and chest CT in children: comparison with body plethysmography.

1995 ◽  
Vol 165 (1) ◽  
pp. 151-154 ◽  
Author(s):  
A E Schlesinger ◽  
D K White ◽  
G B Mallory ◽  
C F Hildeboldt ◽  
C B Huddleston
Keyword(s):  
Chest Radiography ◽  
Total Lung Capacity ◽  
Chest Ct ◽  
Body Plethysmography ◽  
Lung Capacity

THEORETICAL AND METHODOLOGICAL ASPECTS OF BODY PLETHYSMOGRAPHY AND CLINICAL APPLICATIONS

2016 ◽  
Vol 1 (60) ◽  
pp. 117-124 ◽  
Author(s):  
Савушкина ◽  
Olga Savushkina ◽  
Черняк ◽  
Aleksandr Chernyak
Keyword(s):  
Airway Obstruction ◽  
Total Lung Capacity ◽  
Pulmonary Ventilation ◽  
Ideal Gas ◽  
Absolute Pressure ◽  
Body Plethysmography ◽  
Fixed Amount ◽  
Predictive Values ◽  
Lung Capacity ◽  
Residual Capacity

One of the methods to evaluate lung function is body plethysmography. Body plethysmography allows to measure indicators that cannot be obtained during spirometry, that is: total lung capacity (TLC), bronchial resistance (Raw), and functional residual capacity (FRC). FRC measured by body plethysmography reflects thoracic gas volume (TGV or VTG), and includes both ventilated and poorly ventilated volume. Plethysmographic measurements are based on the principle of the relationship between pressure and volume at constant temperature and fixed amount of gas. This principle states that the absolute pressure exerted by a given mass of an ideal gas is inversely proportional to the volume it occupies if the temperature and amount of gas remain unchanged within a closed system (Boyle-Mariotte Law). In body plethysmography, the following parameters: TGV, vital capacity (VC), expiratory reserve volume (ERV), tidal volume (TV), inspiratory reserve volume (IRV), inspiratory capacity (IC), Raw are obtained. TLC, residual volume (RV) and its share in total lung capacity can be calculated. Reduced TLC allows to diagnose restrictive disorders of pulmonary ventilation. The RV and its share in TLC increase together with airway obstruction indicates air trapping. The TGV increase together with airway obstruction indicates hyperinflation. In the analysis of lung volumes predictive values, which are calculated by the formulas recommended by ATS/ERS statement, are used. The results are expressed as a percentage of the predicted value. Thus, body plethysmography is an important addition to spirometry and image methods of research, allowing to assess the functional state of the lungs more objectively; it helps to conduct the differential diagnosis and control the course of the disease.

A Critical Appraisal of a Rapid Radiographic Method of Determining Total Lung Capacity

1986 ◽  
Vol 31 (2) ◽  
pp. 99-102 ◽  
Author(s):  
B. Teklu ◽  
W.M. Gray ◽  
R.J. Mills ◽  
F. Moran
Keyword(s):  
Lung Disease ◽  
Critical Appraisal ◽  
Total Lung Capacity ◽  
Normal Subjects ◽  
Regression Equations ◽  
X Ray ◽  
Lung Capacity ◽  
Radiographic Method ◽  
Trained Personnel ◽  
Single Set

We have demonstrated that the total lung capacities of normal Caucasian adults, can be satisfactorily estimated by means of a regression equation derived from a single set of three measurements taken from a specially exposed plain X-ray film of the chest. However, these equations differ from those found by workers who have studied patients with lung disease. It is concluded from this that different regression equations are to be expected for normal and diseased lungs, and that, the appropriate equation will depend not only on the presence of disease, but also on its type and severity. It is also concluded that the rapid radiographic method of estimating total lung capacity can make little contribution to the diagnostic assessment of lung disease. However, the regression equations appropriate to particular ethnic groups could be used to measure TLC in normal subjects rapidly and inexpensively in places where specialised respiratory equipment and trained personnel are lacking.

scholarly journals Total lung capacity without plethysmography

2018 ◽  
Author(s):  
Ori Adam ◽  
Inon Cohen ◽  
Wai-Ki Yip ◽  
Robert J. Shiner ◽  
Peter Calverley ◽  
...  
Keyword(s):  
Total Lung Capacity ◽  
Airflow Obstruction ◽  
Heterogeneous Population ◽  
Repeated Measurements ◽  
Body Plethysmography ◽  
Individual Subject ◽  
Thoracic Imaging ◽  
Lung Inflation ◽  
Lung Capacity

ABSTRACTBackgroundAmong the most basic measures of respiratory function is the total lung capacity (TLC). TLC is the pulmonary gas volume at maximal lung inflation, which is the sum of the volume of gas that can be exhaled –the vital capacity (VC)– and the volume of gas that cannot –the residual volume (RV). Determination of VC requires only spirometry whereas determination of RV or TLC requires body plethysmography, gas dilution or washout, or thoracic imaging, each of which is more complex than spirometry, and none of which is suited to routine office practice, population screening, or community medicine. To fill this gap, we describe here a new approach to determine TLC without plethysmography.MethodsIn a heterogeneous population of 434 volunteers (265 male, 169 female; 201 healthy, 170 with airflow obstruction, and 63 with ventilatory restriction), we determined TLC in the standard fashion using conventional body plethysmography (TLCpleth). In the same individuals, we also determined TLC in a novel fashion using the MiniBox ™ (TLCMB). To obtain TLCMB, population-based data from traditional spirometry together with flow-interruption transients were subjected to data mining and machine-learning to create for each individual subject an unbiased statistical determination of TLC.ResultsFor the combined heterogeneous population, we found TLCpleth = 1.02TLCMB −0.091 L, adjusted r2=0.824. For the heterogeneous population as a whole, and for each subpopulation, TLCMB closely tracked TLCpleth. For 26 healthy subjects measured on different days, the coefficient of variation for repeated measurements in was 3.3% for TLCpleth versus 1.6% for TLCMB.ConclusionsThese results establish the validity and potential utility of a new method for rapid, accurate, and repeatable determination of TLC in a heterogeneous patient population, but without the need of a plethysmograph.

Radiographie and Plethysmographie Determination of Total Lung Capacity

Radiology ◽  
1966 ◽  
Vol 86 (1) ◽  
pp. 7-30 ◽  
Author(s):  
Herbert M. Loyd ◽  
S. Timothy String ◽  
Arthur B. DuBois
Keyword(s):  
Total Lung Capacity ◽  
Lung Capacity

STUDIES OF RESPIRATORY PHYSIOLOGY IN CHILDREN

PEDIATRICS ◽  
1959 ◽  
Vol 24 (2) ◽  
pp. 181-193
Author(s):  
C. D. Cook ◽  
P. J. Helliesen ◽  
L. Kulczycki ◽  
H. Barrie ◽  
L. Friedlander ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Respiratory Rate ◽  
Vital Capacity ◽  
Total Lung Capacity ◽  
Lung Compliance ◽  
Respiratory Physiology ◽  
Residual Volume ◽  
Lung Volumes ◽  
Lung Capacity ◽  
Residual Capacity

Tidal volume, respiratory rate and lung volumes have been measured in 64 patients with cystic fibrosis of the pancreas while lung compliance and resistance were measured in 42 of these. Serial studies of lung volumes were done in 43. Tidal volume was reduced and the respiratory rate increased only in the most severely ill patients. Excluding the three patients with lobectomies, residual volume and functional residual capacity were found to be significantly increased in 46 and 21%, respectively. These changes correlated well with the roentgenographic evaluation of emphysema. Vital capacity was significantly reduced in 34% while total lung capacity was, on the average, relatively unchanged. Seventy per cent of the 61 patients had a signficantly elevated RV/TLC ratio. Lung compliance was significantly reduced in only the most severely ill patients but resistance was significantly increased in 35% of the patients studied. The serial studies of lung volumes showed no consistent trends among the groups of patients in the period between studies. However, 10% of the surviving patients showed evidence of significant improvement while 15% deteriorated. [See Fig. 8. in Source Pdf.] Although there were individual discrepancies, there was a definite correlation between the clinical evaluation and tests of respiratory function, especially the changes in residual volume, the vital capacity, RV/ TLC ratio and the lung compliance and resistance.

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