scholarly journals Diabetic cardiomyopathy and reactive oxygen species (ROS) related parameters in male and female rats: A comparative study

2007 ◽  
Vol 22 (1) ◽  
pp. 84-90 ◽  
Author(s):  
Vidya Akhileshwar ◽  
Samir P. Patel ◽  
Surendra S. Katyare
Keyword(s):  
Reactive Oxygen Species ◽  
Comparative Study ◽  
Diabetic Cardiomyopathy ◽  
Reactive Oxygen ◽  
Female Rats ◽  
Oxygen Species ◽  
Male And Female ◽  
Male And Female Rats

scholarly journals Production and scavenging of reactive oxygen species both affect reproductive success in male and female Drosophila melanogaster

2021 ◽  
Author(s):  
Biz R. Turnell ◽  
Luisa Kumpitsch ◽  
Klaus Reinhardt
Keyword(s):  
Reactive Oxygen Species ◽  
Drosophila Melanogaster ◽  
Reactive Oxygen ◽  
Cellular Aging ◽  
Ros Production ◽  
Oxygen Species ◽  
Wild Type ◽  
Ros Scavenging ◽  
Respiratory Pathway ◽  
Male And Female

AbstractSperm aging is accelerated by the buildup of reactive oxygen species (ROS), which cause oxidative damage to various cellular components. Aging can be slowed by limiting the production of mitochondrial ROS and by increasing the production of antioxidants, both of which can be generated in the sperm cell itself or in the surrounding somatic tissues of the male and female reproductive tracts. However, few studies have compared the separate contributions of ROS production and ROS scavenging to sperm aging, or to cellular aging in general. We measured reproductive fitness in two lines of Drosophila melanogaster genetically engineered to (1) produce fewer ROS via expression of alternative oxidase (AOX), an alternative respiratory pathway; or (2) scavenge fewer ROS due to a loss-of-function mutation in the antioxidant gene dj-1β. Wild-type females mated to AOX males had increased fecundity and longer fertility durations, consistent with slower aging in AOX sperm. Contrary to expectations, fitness was not reduced in wild-type females mated to dj-1β males. Fecundity and fertility duration were increased in AOX and decreased in dj-1β females, indicating that female ROS levels may affect aging rates in stored sperm and/or eggs. Finally, we found evidence that accelerated aging in dj-1β sperm may have selected for more frequent mating. Our results help to clarify the relative roles of ROS production and ROS scavenging in the male and female reproductive systems.

Comparative study of the sensitivity of male and female rats to methylmercury

1981 ◽  
Vol 48 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Laszlo Magos ◽  
George C. Peristianis ◽  
Thomas W. Clarkson ◽  
Alwyn Brown ◽  
Stanley Preston ◽  
...  
Keyword(s):  
Comparative Study ◽  
Female Rats ◽  
Male And Female ◽  
Male And Female Rats
Sign in / Sign up

Export Citation Format

Share Document