Biological diagnosis of pancreatic ductal obstruction

1984 ◽  
Vol 14 (3) ◽  
pp. 413-415
Author(s):  
Antonio M. García-Pugés ◽  
Montserrat Elena ◽  
Salvador Navarro ◽  
Elena Casals ◽  
Antonio M. Ballesta ◽  
...  
Keyword(s):  
Pancreatic Ductal Obstruction

Mechanism of canine gastric hypersecretion after complete pancreatic ductal obstruction

1963 ◽  
Vol 205 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Michael F. Hein ◽  
William Silen ◽  
Harold A. Harper
Keyword(s):  
Control Diet ◽  
Hepatic Function ◽  
Pancreatic Enzymes ◽  
Pancreatic Ducts ◽  
Base Line ◽  
Pancreatic Duct Ligation ◽  
Hepatocellular Damage ◽  
Gastric Hypersecretion ◽  
Duct Ligation ◽  
Pancreatic Ductal Obstruction

The effect of pancreatic enzymes (Viokase) on the gastric hypersecretion induced by pancreatic ductal ligation was studied in seven dogs with Heidenhain pouches. The pancreatic ducts were completely ligated after base-line determinations of the daily output of acid and secretory response of the pouches to histamine and tests of hepatic function. The influence on these tests of the preligation control diet and the following experimental diets was studied after the pancreatic duct ligation in varying sequence for 5–47 days: 1) control diet incubated with Viokase; 2) control diet mixed but not incubated with Viokase; 3) control diet incubated with heat-inactivated Viokase. Complete ligation of the pancreatic ducts was followed by marked gastric hypersecretion while the dogs were fed the control diet. Both the diet incubated with Viokase and the diet mixed with Viokase and then allowed to stand for 1–3 hr before feeding caused significant reduction of such hypersecretion. Evidence of hepatocellular damage was found after pancreatic ductal obstruction when active pancreatic enzymes were not added to the control diet.

Acute Suppuration of the Pancreatic Duct Associated with Pancreatic Ductal Obstruction Due to Pancreas Carcinoma

Pancreas ◽  
2006 ◽  
Vol 33 (2) ◽  
pp. 195-197 ◽  
Author(s):  
Yoshitsugu Tajima ◽  
Tamotsu Kuroki ◽  
Seiya Susumu ◽  
Ryuji Tsutsumi ◽  
Amane Kitasato ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreas Carcinoma ◽  
Pancreatic Ductal Obstruction

Is There Pancreatic Ductal Obstruction in Chronic Pancreatitis?

1959 ◽  
Vol 36 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Henry D. Janowitz ◽  
David A. Dreiling
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Ductal Obstruction

Endoscopic Therapy for Complete Pancreatic Ductal Obstruction in a Child With Hereditary Pancreatitis

2016 ◽  
Vol 62 (1) ◽  
pp. e2-e4
Author(s):  
Amy J. Virojanapa ◽  
Punit Jhaveri ◽  
Charles Dye ◽  
Abraham Mathew ◽  
Chandran P. Alexander
Keyword(s):  
Endoscopic Therapy ◽  
Hereditary Pancreatitis ◽  
Pancreatic Ductal Obstruction

scholarly journals Acute Obstructive Suppuration of the Pancreatic Duct Causing Sepsis

2017 ◽  
Vol 31 (1&2) ◽  
pp. 20
Author(s):  
Stanley Yakubov ◽  
Jack Braha ◽  
Joel Albert ◽  
Rabin Rahmani ◽  
Ira Mayer ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Pancreatic Duct ◽  
English Literature ◽  
Recurrent Acute Pancreatitis ◽  
Laboratory Test Results ◽  
History Of ◽  
Pancreatic Ductal Obstruction ◽  
Pancreatic Duct Stones ◽  
Endoscopic Methods ◽  
Pigtail Stent

Objective: We report a rare case of acute obstructive suppuration of the pancreatic duct causing sepsis, which was successfully treated with emergent endoscopic retrograde cholangiopancreatography (ERCP). Methods: We describe the patient’s clinical presentation, laboratory test results, and imaging used for diagnosis and treatment. Results: A 33-year-old female with a history of recurrent acute pancreatitis was admitted during an episode of acute pancreatitis. Computed tomography (CT) scan of the abdomen revealed acute pancreatitis, diffuse pancreatic atrophy and pancreatic ductal dilatation with obstruction due to a soft tissue lesion within the distal duct. Shortly after admission she developed symptoms and signs of sepsis. Urgent ERCP was performed to further assess the suspected cholangitis. “Clean” bile emanated from the common bile duct, while copious purulent fluid was detected at the dilated pancreatic duct orifice, confirming suppuration of the pancreatic duct. A plastic single pigtail stent was placed traversing the ampulla and pancreatic duct stones that were causing the obstruction, which were later removed. After endoscopic decompression, the patient rapidly improved over the following 24 hours and had no subsequent admissions for pancreatitis.Conclusion: Acute suppuration of the pancreatic duct (ASPD) is a rare and potentially fatal infectious complication of pancreatic ductal obstruction with few cases reported in the English literature. It would be of interest to further investigate the exact pathophysiology leading to development of ASPD. The endoscopic methods of urgent ERCP and pancreatic duct decompression utilized in our case proved effective in successfully treating ASPD. This unusual condition should be considered in patients with acute pancreatitis who develop early clinical decompensation. 

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