Hydrocortisone: Inhibition of DNA synthesis and mitotic rate after local application to mouse epidermis

1971 ◽  
Vol 8 (1) ◽  
pp. 42-49
Author(s):  
H. Hennings ◽  
K. Elgjo
Keyword(s):  
Dna Synthesis ◽  
Mitotic Rate ◽  
Local Application ◽  
Mouse Epidermis ◽  
Inhibition Of Dna Synthesis

Inhibition of DNA synthesis in mouse epidermis and breast epithelium by dehydroepiandrosterone and related steroids

1981 ◽  
Vol 2 (8) ◽  
pp. 717-721 ◽  
Author(s):  
Laura L. Pashko ◽  
Arthur G. Schwartz ◽  
Magid Abou-Gharbia ◽  
Daniel Swern
Keyword(s):  
Dna Synthesis ◽  
Mouse Epidermis ◽  
Breast Epithelium ◽  
Inhibition Of Dna Synthesis

CONTROL OF NUCLEAR PROCESSES BY AUXIN IN AXILLARY BUDS OF TRADESCANTIA PALUDOSA

1958 ◽  
Vol 36 (2) ◽  
pp. 221-232 ◽  
Author(s):  
J. M. Naylor
Keyword(s):  
Dna Synthesis ◽  
Mitotic Rate ◽  
Axillary Buds ◽  
Naphthalene Acetic Acid ◽  
Terminal Bud ◽  
Lateral Bud ◽  
Regulatory Effects ◽  
Inhibition Of Dna Synthesis ◽  
Nuclear Processes ◽  
Tradescantia Paludosa

Regulatory effects of auxin on mitosis and DNA synthesis were studied in lateral bud apices of Tradescnntia paludosa. In axillary buds inhibited by the terminal bud, mitoses were absent in a group of cells constituting the initials of tunica and corpus within the apex. The DNA (Feulgen) content of inter-phasic nuclei in this "zone of inhibition" was uniform and no greater than that characteristic of diploid telophase (2C), despite differences in nuclear volume. In subapical bud tissues, mitoses occurred at a low rate. Upon removal of the vegetative shoot tip, this mitotic rate was increased and the previously inhibited nuclei within the apes underwent DNA doubling to 4C, then entered prophase. These results indicate that the interphase synthesis of at least one chromosomal substance (DNA) is under auxin control. Evidence is presented that mitosis is not directly inhibited by this hormone. Naphthalene acetic acid was found to substitute for natural auxin in the inhibition of DNA synthesis.

scholarly journals Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies.

1992 ◽  
Vol 267 (2) ◽  
pp. 691-694 ◽  
Author(s):  
V J LaMorte ◽  
P K Goldsmith ◽  
A M Spiegel ◽  
J L Meinkoth ◽  
J R Feramisco
Keyword(s):  
Dna Synthesis ◽  
Living Cells ◽  
Inhibition Of Dna Synthesis

The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology

1990 ◽  
Vol 25 (6) ◽  
pp. 418-424 ◽  
Author(s):  
Li-Ming Wang ◽  
J. Courtland White ◽  
Robert L. Capizzi
Keyword(s):  
Dna Synthesis ◽  
Cellular Pharmacology ◽  
Inhibition Of Dna Synthesis
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